6IP0
Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with AKG
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue AKG A 601 |
| Chain | Residue |
| A | TYR282 |
| A | NI602 |
| A | SO4615 |
| A | HOH703 |
| A | PHE290 |
| A | HIS293 |
| A | GLU295 |
| A | SER301 |
| A | ASN303 |
| A | LYS311 |
| A | TRP313 |
| A | HIS388 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue NI A 602 |
| Chain | Residue |
| A | HIS293 |
| A | GLU295 |
| A | HIS388 |
| A | AKG601 |
| A | HOH703 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 603 |
| Chain | Residue |
| A | CYS500 |
| A | CYS503 |
| A | CYS522 |
| A | HIS525 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 604 |
| Chain | Residue |
| A | CYS514 |
| A | CYS516 |
| A | HIS519 |
| A | CYS534 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | THR488 |
| A | LEU542 |
| A | ARG543 |
| A | ASP544 |
| A | HOH701 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | PRO426 |
| A | LEU427 |
| A | LEU428 |
| A | PRO429 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 607 |
| Chain | Residue |
| A | TYR495 |
| A | PHE511 |
| A | ASN513 |
| A | TYR517 |
| A | HOH753 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 608 |
| Chain | Residue |
| A | ARG188 |
| A | ALA199 |
| A | ARG200 |
| A | CYS203 |
| A | SO4609 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 609 |
| Chain | Residue |
| A | ARG188 |
| A | LYS192 |
| A | LYS196 |
| A | ARG200 |
| A | SO4608 |
| A | SO4612 |
| A | SO4612 |
| A | HOH786 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 610 |
| Chain | Residue |
| A | ARG188 |
| A | LYS192 |
| A | ASN195 |
| A | ASN195 |
| A | LYS196 |
| A | LYS196 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 611 |
| Chain | Residue |
| A | LYS153 |
| A | SER154 |
| A | HOH714 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 612 |
| Chain | Residue |
| A | LYS192 |
| A | LYS192 |
| A | LYS196 |
| A | LYS196 |
| A | TYR517 |
| A | TYR517 |
| A | SO4609 |
| A | SO4609 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 613 |
| Chain | Residue |
| A | PHE411 |
| A | ILE414 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 614 |
| Chain | Residue |
| A | LYS157 |
| A | THR184 |
| A | THR186 |
| A | TYR495 |
| A | GLY496 |
| A | HOH800 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 615 |
| Chain | Residue |
| A | TYR231 |
| A | ILE283 |
| A | GLY284 |
| A | SER288 |
| A | MET289 |
| A | LYS311 |
| A | SER392 |
| A | AKG601 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 616 |
| Chain | Residue |
| A | ALA346 |
| A | PHE347 |
| A | ARG418 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 617 |
| Chain | Residue |
| A | HIS525 |
| A | ASP526 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 41 |
| Details | Domain: {"description":"JmjN","evidences":[{"source":"PROSITE-ProRule","id":"PRU00537","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 170 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 51 |
| Details | Zinc finger: {"description":"C5HC2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30899015","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6IP0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IP4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30899015","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IP0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IP4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Site: {"description":"Histone H3 binding","evidences":[{"source":"PubMed","id":"30899015","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IP4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
