6INS

X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
F	0005179	molecular_function	hormone activity
F	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN F 30

Chain	Residue
F	HIS10
F	HIS10
F	HIS10
F	HOH81
F	HOH81
F	HOH81

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN E 30

Chain	Residue
E	HOH31
E	HOH31
E	HOH31
E	HIS10
E	HIS10
E	HIS10

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Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCTSiCSlyqLenyC

Chain	Residue	Details
E	CYS6-CYS20

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Peptide: {"description":"Insulin A chain","featureId":"PRO_0000015881"}

Chain

Residue

Details

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