6IIE

Crystal structure of human diacylglycerol kinase alpha EF-hand domains bound to Ca2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 201

Chain	Residue
A	ASP123
A	ASP125
A	ASN127
A	ILE129
A	GLU134
A	HOH301

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site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 202

Chain	Residue
A	SER174
A	GLU179
A	HOH309
A	ASP168
A	ASP170
A	SER172

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 203

Chain	Residue
A	THR124
A	ARG126
A	GLY184
A	THR186
A	PRO189

---

site_id	AC4
Number of Residues	3
Details	binding site for residue GOL A 204

Chain	Residue
A	GLN141
A	TYR148
A	PG4206

---

site_id	AC5
Number of Residues	1
Details	binding site for residue PG4 A 205

Chain	Residue
A	TRP151

---

site_id	AC6
Number of Residues	3
Details	binding site for residue PG4 A 206

Chain	Residue
A	GLY195
A	GOL204
A	HOH302

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DTDRNGILDssEV

Chain	Residue	Details
A	ASP123-VAL135
A	ASP168-TRP180

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30653270","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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