6IIA

MexB in complex with LMNG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0009636	biological_process	response to toxic substance
A	0015297	molecular_function	antiporter activity
A	0015562	molecular_function	efflux transmembrane transporter activity
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0042908	biological_process	xenobiotic transport
A	0042910	molecular_function	xenobiotic transmembrane transporter activity
A	0046677	biological_process	response to antibiotic
A	0055085	biological_process	transmembrane transport
A	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
A	1990281	cellular_component	efflux pump complex
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0009636	biological_process	response to toxic substance
B	0015297	molecular_function	antiporter activity
B	0015562	molecular_function	efflux transmembrane transporter activity
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0042908	biological_process	xenobiotic transport
B	0042910	molecular_function	xenobiotic transmembrane transporter activity
B	0046677	biological_process	response to antibiotic
B	0055085	biological_process	transmembrane transport
B	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
B	1990281	cellular_component	efflux pump complex
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0009636	biological_process	response to toxic substance
C	0015297	molecular_function	antiporter activity
C	0015562	molecular_function	efflux transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0022857	molecular_function	transmembrane transporter activity
C	0042908	biological_process	xenobiotic transport
C	0042910	molecular_function	xenobiotic transmembrane transporter activity
C	0046677	biological_process	response to antibiotic
C	0055085	biological_process	transmembrane transport
C	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
C	1990281	cellular_component	efflux pump complex
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0009636	biological_process	response to toxic substance
D	0015297	molecular_function	antiporter activity
D	0015562	molecular_function	efflux transmembrane transporter activity
D	0016020	cellular_component	membrane
D	0022857	molecular_function	transmembrane transporter activity
D	0042908	biological_process	xenobiotic transport
D	0042910	molecular_function	xenobiotic transmembrane transporter activity
D	0046677	biological_process	response to antibiotic
D	0055085	biological_process	transmembrane transport
D	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
D	1990281	cellular_component	efflux pump complex
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0009636	biological_process	response to toxic substance
E	0015297	molecular_function	antiporter activity
E	0015562	molecular_function	efflux transmembrane transporter activity
E	0016020	cellular_component	membrane
E	0022857	molecular_function	transmembrane transporter activity
E	0042908	biological_process	xenobiotic transport
E	0042910	molecular_function	xenobiotic transmembrane transporter activity
E	0046677	biological_process	response to antibiotic
E	0055085	biological_process	transmembrane transport
E	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
E	1990281	cellular_component	efflux pump complex
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0009636	biological_process	response to toxic substance
F	0015297	molecular_function	antiporter activity
F	0015562	molecular_function	efflux transmembrane transporter activity
F	0016020	cellular_component	membrane
F	0022857	molecular_function	transmembrane transporter activity
F	0042908	biological_process	xenobiotic transport
F	0042910	molecular_function	xenobiotic transmembrane transporter activity
F	0046677	biological_process	response to antibiotic
F	0055085	biological_process	transmembrane transport
F	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
F	1990281	cellular_component	efflux pump complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue AV0 B 1101

Chain	Residue
B	GLN46
B	GLY179
B	SER180
B	GLN273
B	ASP274
B	VAL612
B	PHE615
B	ARG620
B	PHE628
B	LEU672
B	SER48
B	GLU81
B	THR89
B	ARG128
B	LYS134
B	GLN176
B	VAL177
B	PHE178

---

site_id	AC2
Number of Residues	17
Details	binding site for residue AV0 E 1101

Chain	Residue
E	GLN46
E	SER48
E	GLU81
E	THR89
E	LYS134
E	PHE136
E	VAL139
E	VAL177
E	PHE178
E	GLY179
E	SER180
E	GLN273
E	ASP274
E	TYR327
E	ARG620
E	PHE628
E	MET630

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	590
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"10187844","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1404
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3629
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"10187844","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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