6IH3
Crystal structure of Phosphite Dehydrogenase from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005829 | cellular_component | cytosol |
A | 0008465 | molecular_function | hydroxypyruvate reductase (NADH) activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0030267 | molecular_function | glyoxylate reductase (NADPH) activity |
A | 0051287 | molecular_function | NAD binding |
B | 0005829 | cellular_component | cytosol |
B | 0008465 | molecular_function | hydroxypyruvate reductase (NADH) activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
B | 0030267 | molecular_function | glyoxylate reductase (NADPH) activity |
B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | binding site for residue A7R A 400 |
Chain | Residue |
A | THR104 |
A | ALA235 |
A | CYS236 |
A | ASP261 |
A | HIS293 |
A | GLY295 |
A | HOH544 |
A | HOH548 |
A | HOH574 |
A | HOH615 |
A | HOH647 |
A | GLY152 |
A | HOH665 |
A | HOH677 |
A | HOH714 |
A | HOH730 |
A | GLY154 |
A | ALA155 |
A | VAL156 |
A | ASP175 |
A | PRO176 |
A | MET207 |
A | VAL208 |
Functional Information from PROSITE/UniProt
site_id | PS00065 |
Number of Residues | 28 |
Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. LGIIGmGAVGraiaqrlagfemn.LLyCD |
Chain | Residue | Details |
A | LEU148-ASP175 |
site_id | PS00671 |
Number of Residues | 17 |
Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKtGsYLINaCRGsVVD |
Chain | Residue | Details |
A | MET226-ASP242 |