6IED
Crystal structure of heme A synthase from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0006784 | biological_process | heme A biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0120547 | molecular_function | heme A synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue HEM A 601 |
| Chain | Residue |
| A | ARG37 |
| A | ILE255 |
| A | GLN258 |
| A | GLY262 |
| A | LEU270 |
| A | HIS278 |
| A | VAL176 |
| A | GLY179 |
| A | ALA180 |
| A | ARG183 |
| A | SER188 |
| A | HIS216 |
| A | ARG217 |
| A | ALA220 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CU A 602 |
| Chain | Residue |
| A | MET-4 |
| A | GLU-2 |
| A | ASP145 |
| A | HIS209 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | THR27 |
| A | LYS28 |
| A | THR29 |
| A | ARG183 |
| A | HIS184 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | GLY158 |
| A | LYS159 |
| A | LYS160 |
| A | MET161 |
| A | HIS233 |
| A | TYR238 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue OLC A 605 |
| Chain | Residue |
| A | ARG87 |
| A | GLU88 |
| A | PHE91 |
| A | LEU92 |
| A | MET95 |
| A | ILE170 |
| A | CYS290 |
| A | LEU294 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 606 |
| Chain | Residue |
| A | LEU139 |
| A | PHE142 |
| A | GLU143 |
| A | LYS146 |
| A | THR150 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 26 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01664","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"HAMAP-Rule","id":"MF_01664","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"HAMAP-Rule","id":"MF_01664","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30397130","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
