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6ICE

Crystal structure of Hamster MIF

Functional Information from GO Data
ChainGOidnamespacecontents
A0002020molecular_functionprotease binding
A0002906biological_processnegative regulation of mature B cell apoptotic process
A0004167molecular_functiondopachrome isomerase activity
A0005125molecular_functioncytokine activity
A0005576cellular_componentextracellular region
A0005737cellular_componentcytoplasm
A0007165biological_processsignal transduction
A0031666biological_processpositive regulation of lipopolysaccharide-mediated signaling pathway
A0032308biological_processpositive regulation of prostaglandin secretion
A0033033biological_processnegative regulation of myeloid cell apoptotic process
A0043066biological_processnegative regulation of apoptotic process
A0043518biological_processnegative regulation of DNA damage response, signal transduction by p53 class mediator
A0045089biological_processpositive regulation of innate immune response
A0048146biological_processpositive regulation of fibroblast proliferation
A0050178molecular_functionphenylpyruvate tautomerase activity
A0061081biological_processpositive regulation of myeloid leukocyte cytokine production involved in immune response
A0070374biological_processpositive regulation of ERK1 and ERK2 cascade
A0080135biological_processregulation of cellular response to stress
A0090238biological_processpositive regulation of arachidonate secretion
A2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
B0002020molecular_functionprotease binding
B0002906biological_processnegative regulation of mature B cell apoptotic process
B0004167molecular_functiondopachrome isomerase activity
B0005125molecular_functioncytokine activity
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0007165biological_processsignal transduction
B0031666biological_processpositive regulation of lipopolysaccharide-mediated signaling pathway
B0032308biological_processpositive regulation of prostaglandin secretion
B0033033biological_processnegative regulation of myeloid cell apoptotic process
B0043066biological_processnegative regulation of apoptotic process
B0043518biological_processnegative regulation of DNA damage response, signal transduction by p53 class mediator
B0045089biological_processpositive regulation of innate immune response
B0048146biological_processpositive regulation of fibroblast proliferation
B0050178molecular_functionphenylpyruvate tautomerase activity
B0061081biological_processpositive regulation of myeloid leukocyte cytokine production involved in immune response
B0070374biological_processpositive regulation of ERK1 and ERK2 cascade
B0080135biological_processregulation of cellular response to stress
B0090238biological_processpositive regulation of arachidonate secretion
B2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
C0002020molecular_functionprotease binding
C0002906biological_processnegative regulation of mature B cell apoptotic process
C0004167molecular_functiondopachrome isomerase activity
C0005125molecular_functioncytokine activity
C0005576cellular_componentextracellular region
C0005737cellular_componentcytoplasm
C0007165biological_processsignal transduction
C0031666biological_processpositive regulation of lipopolysaccharide-mediated signaling pathway
C0032308biological_processpositive regulation of prostaglandin secretion
C0033033biological_processnegative regulation of myeloid cell apoptotic process
C0043066biological_processnegative regulation of apoptotic process
C0043518biological_processnegative regulation of DNA damage response, signal transduction by p53 class mediator
C0045089biological_processpositive regulation of innate immune response
C0048146biological_processpositive regulation of fibroblast proliferation
C0050178molecular_functionphenylpyruvate tautomerase activity
C0061081biological_processpositive regulation of myeloid leukocyte cytokine production involved in immune response
C0070374biological_processpositive regulation of ERK1 and ERK2 cascade
C0080135biological_processregulation of cellular response to stress
C0090238biological_processpositive regulation of arachidonate secretion
C2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
Functional Information from PROSITE/UniProt
site_idPS01158
Number of Residues15
DetailsMIF Macrophage migration inhibitory factor family signature. DPCAlcsLhSIGkIG
ChainResidueDetails
AASP54-GLY68

254227

PDB entries from 2026-05-27

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