6ICA

The crystal structure of Legionella pneumophila LapA aminopeptidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0006508	biological_process	proteolysis
A	0008235	molecular_function	metalloexopeptidase activity
A	0046872	molecular_function	metal ion binding
B	0004177	molecular_function	aminopeptidase activity
B	0006508	biological_process	proteolysis
B	0008235	molecular_function	metalloexopeptidase activity
B	0046872	molecular_function	metal ion binding
C	0004177	molecular_function	aminopeptidase activity
C	0006508	biological_process	proteolysis
C	0008235	molecular_function	metalloexopeptidase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 501

Chain	Residue
A	LYS179
A	ASP180
A	LYS216
A	GOL502
A	HOH617
A	HOH662

---

site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 502

Chain	Residue
C	SER159
C	GLU403
C	THR406
C	HOH729
A	SO4501
A	HOH613
A	HOH771

---

site_id	AC3
Number of Residues	10
Details	binding site for residue GOL A 503

Chain	Residue
A	ARG318
A	ASN319
A	ASP320
A	ASP323
A	THR325
A	TRP327
A	GLU380
A	THR381
A	HOH629
A	HOH770

---

site_id	AC4
Number of Residues	6
Details	binding site for residue ZN A 504

Chain	Residue
A	HIS238
A	ASP251
A	ASP313
A	ZN505
A	HOH653
A	HOH784

---

site_id	AC5
Number of Residues	5
Details	binding site for residue ZN A 505

Chain	Residue
A	ASP251
A	GLU286
A	HIS391
A	ZN504
A	HOH653

---

site_id	AC6
Number of Residues	2
Details	binding site for residue ACT A 506

Chain	Residue
A	TYR332
A	HOH696

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ACT A 507

Chain	Residue
A	SER83
A	SER84
A	THR178
A	ASP243

---

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 A 508

Chain	Residue
A	PHE209
A	VAL210
A	LYS211
A	HIS298
A	HOH636

---

site_id	AC9
Number of Residues	7
Details	binding site for residue SO4 A 509

Chain	Residue
A	THR170
A	PRO247
A	LYS396
A	MET397
A	HOH601
A	HOH602
A	HOH652

---

site_id	AD1
Number of Residues	6
Details	binding site for residue SO4 B 501

Chain	Residue
B	LYS179
B	ASP180
B	LYS216
B	HOH601
B	HOH604
B	HOH609

---

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 B 502

Chain	Residue
B	PRO231
B	ARG275
B	LYS307
B	GLU424
B	HOH671

---

site_id	AD3
Number of Residues	9
Details	binding site for residue GOL B 503

Chain	Residue
B	ARG318
B	ASN319
B	ASP320
B	ASP323
B	THR325
B	TRP327
B	GLU380
B	THR381
B	HOH631

---

site_id	AD4
Number of Residues	5
Details	binding site for residue ZN B 504

Chain	Residue
B	HIS238
B	ASP251
B	ASP313
B	ZN505
B	HOH745

---

site_id	AD5
Number of Residues	4
Details	binding site for residue ZN B 505

Chain	Residue
B	ASP251
B	GLU286
B	HIS391
B	ZN504

---

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 B 506

Chain	Residue
B	PHE209
B	LYS211
B	HOH613
B	HOH678

---

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 B 507

Chain	Residue
B	ARG335
B	HOH617
C	HOH752

---

site_id	AD8
Number of Residues	3
Details	binding site for residue SO4 C 501

Chain	Residue
C	LYS216
C	HOH632
C	HOH757

---

site_id	AD9
Number of Residues	8
Details	binding site for residue GOL C 502

Chain	Residue
C	ASN319
C	ASP320
C	ASP323
C	THR325
C	TRP327
C	GLU380
C	THR381
C	HOH682

---

site_id	AE1
Number of Residues	8
Details	binding site for residue GOL C 503

Chain	Residue
B	SER159
B	GLU403
B	HOH634
C	ASN174
C	LYS179
C	ASP180
C	THR181
C	HOH663

---

site_id	AE2
Number of Residues	6
Details	binding site for residue ZN C 504

Chain	Residue
C	HIS238
C	ASP251
C	ASP313
C	ZN505
C	HOH688
C	HOH783

---

site_id	AE3
Number of Residues	6
Details	binding site for residue ZN C 505

Chain	Residue
C	ASP251
C	GLU286
C	HIS391
C	ZN504
C	HOH688
C	HOH806

---

site_id	AE4
Number of Residues	5
Details	binding site for residue SO4 C 506

Chain	Residue
C	PHE209
C	VAL210
C	LYS211
C	HOH610
C	HOH621

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