6I9L
JmjC domain-containing protein 5 (JMJD5) in complex with Mn and pyridine-2,4-dicarboxylic acid (2,4-PDCA)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 501 |
| Chain | Residue |
| A | HIS321 |
| A | ASP323 |
| A | HIS400 |
| A | PD2502 |
| A | HOH664 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue PD2 A 502 |
| Chain | Residue |
| A | ASP323 |
| A | ASN327 |
| A | LEU329 |
| A | LYS336 |
| A | HIS400 |
| A | VAL402 |
| A | SER412 |
| A | TRP414 |
| A | MN501 |
| A | TYR272 |
| A | TRP310 |
| A | SER318 |
| A | HIS321 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue TRS A 503 |
| Chain | Residue |
| A | LEU200 |
| A | VAL201 |
| A | GLY203 |
| A | GLN326 |
| A | TYR350 |
| A | LYS372 |
| A | PHE373 |
| A | VAL396 |
| A | HOH663 |
| A | HOH680 |
| A | HOH737 |
| A | HOH802 |
| A | HOH823 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29459673 |
| Chain | Residue | Details |
| A | GLU238 | |
| A | GLN275 | |
| A | SER318 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22851697, ECO:0000269|PubMed:29459673, ECO:0000269|PubMed:29563586, ECO:0000305|PubMed:24100311, ECO:0007744|PDB:3UYJ, ECO:0007744|PDB:4GJZ, ECO:0007744|PDB:4QU1, ECO:0007744|PDB:5FBJ |
| Chain | Residue | Details |
| A | ASN327 | |
| A | LYS336 | |
| A | TYR272 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000305|PubMed:22851697, ECO:0000305|PubMed:24100311, ECO:0007744|PDB:4GJY, ECO:0007744|PDB:4GJZ |
| Chain | Residue | Details |
| A | HIS321 | |
| A | ASP323 | |
| A | HIS400 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22851697, ECO:0000269|PubMed:29459673, ECO:0000269|PubMed:29563586, ECO:0007744|PDB:3UYJ, ECO:0007744|PDB:4GJZ |
| Chain | Residue | Details |
| A | TRP414 |
