Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 703 |
| Chain | Residue |
| A | ALA543 |
| A | THR544 |
| A | LEU546 |
| A | SER549 |
| A | TYR550 |
| A | ASN551 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 704 |
| Chain | Residue |
| A | SER537 |
| A | ASP542 |
| A | HOH1150 |
| A | TYR402 |
| A | VAL521 |
| A | THR536 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 705 |
| Chain | Residue |
| A | ASP337 |
| A | ASP339 |
| A | PHE341 |
| A | GLU343 |
| A | HOH907 |
| A | HOH919 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 706 |
| Chain | Residue |
| A | ASP313 |
| A | PHE482 |
| A | GLU491 |
| A | HOH1063 |
| A | HOH1136 |
| A | HOH1191 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | binding site for residue H8E A 707 |
| Chain | Residue |
| A | TRP391 |
| A | THR442 |
| A | ALA443 |
| A | HIS444 |
| A | GLY445 |
| A | ALA451 |
| A | ASN475 |
| A | CYS477 |
| A | ILE478 |
| A | ASN510 |
| A | SER511 |
| A | TYR512 |
| A | TRP513 |
| A | ASP516 |
| A | HIS575 |
| A | HOH872 |
| A | HOH897 |
| A | HOH1106 |
| A | HOH1168 |
| A | HOH1479 |
| B | TYR389 |
| B | SER390 |
| B | TRP391 |
| B | GLN394 |
| B | HOH1181 |
| B | HOH1432 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | binding site for residue EPE A 708 |
| Chain | Residue |
| A | ARG243 |
| A | LYS253 |
| A | LEU260 |
| A | TYR269 |
| A | LEU270 |
| A | VAL272 |
| A | TYR274 |
| A | GLY634 |
| A | VAL635 |
| A | LEU636 |
| A | LYS654 |
| A | HOH803 |
| A | HOH818 |
| A | HOH974 |
| A | HOH976 |
| A | HOH1123 |
| A | HOH1188 |
| A | HOH1232 |
| A | HOH1314 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 709 |
| Chain | Residue |
| A | THR282 |
| A | GLN615 |
| A | SER617 |
| A | TYR618 |
| A | HOH860 |
| A | HOH903 |
| A | HOH917 |
| A | HOH943 |
| A | HOH1046 |
| A | HOH1283 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 710 |
| Chain | Residue |
| A | TYR238 |
| A | ASP548 |
| A | SER549 |
| A | ASN551 |
| A | MET594 |
| A | SER669 |
| A | HOH889 |
| A | HOH915 |
| A | HOH1086 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 711 |
| Chain | Residue |
| A | TYR429 |
| A | SER430 |
| A | ASN433 |
| A | GLN459 |
| A | ALA462 |
| A | LEU463 |
| A | HOH876 |
| A | HOH954 |
| A | HOH1259 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 703 |
| Chain | Residue |
| B | LEU546 |
| B | SER549 |
| B | TYR550 |
| B | ASN551 |
| B | ALA543 |
| B | THR544 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 704 |
| Chain | Residue |
| B | TYR402 |
| B | VAL521 |
| B | THR536 |
| B | SER537 |
| B | ASP542 |
| B | HOH1077 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 705 |
| Chain | Residue |
| B | ASP337 |
| B | ASP339 |
| B | PHE341 |
| B | GLU343 |
| B | HOH881 |
| B | HOH913 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 706 |
| Chain | Residue |
| B | ASP313 |
| B | PHE482 |
| B | GLU491 |
| B | HOH1043 |
| B | HOH1137 |
| B | HOH1191 |
| site_id | AD5 |
| Number of Residues | 24 |
| Details | binding site for residue H8E B 707 |
| Chain | Residue |
| A | TYR389 |
| A | SER390 |
| A | TRP391 |
| A | GLN394 |
| A | HOH1179 |
| B | TRP391 |
| B | THR442 |
| B | ALA443 |
| B | HIS444 |
| B | GLY445 |
| B | ALA451 |
| B | ASN475 |
| B | CYS477 |
| B | ILE478 |
| B | ASN510 |
| B | SER511 |
| B | TYR512 |
| B | TRP513 |
| B | ASP516 |
| B | HIS575 |
| B | HOH876 |
| B | HOH896 |
| B | HOH1100 |
| B | HOH1237 |
| site_id | AD6 |
| Number of Residues | 18 |
| Details | binding site for residue EPE B 708 |
| Chain | Residue |
| B | ARG243 |
| B | LEU260 |
| B | TYR269 |
| B | LEU270 |
| B | VAL272 |
| B | TYR274 |
| B | VAL635 |
| B | LEU636 |
| B | HOH842 |
| B | HOH955 |
| B | HOH959 |
| B | HOH964 |
| B | HOH988 |
| B | HOH1036 |
| B | HOH1126 |
| B | HOH1201 |
| B | HOH1351 |
| B | HOH1520 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue DTV B 709 |
| Chain | Residue |
| B | TYR425 |
| B | THR426 |
| B | GLY427 |
| B | CYS428 |
| B | TYR429 |
| B | PRO453 |
| B | LEU454 |
| B | HOH960 |
| B | HOH1046 |
| B | HOH1345 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 710 |
| Chain | Residue |
| B | TYR238 |
| B | ASP548 |
| B | SER549 |
| B | ASN551 |
| B | MET594 |
| B | SER669 |
| B | HOH971 |
| B | HOH1016 |
| B | HOH1026 |
| B | HOH1190 |
| site_id | AD9 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 711 |
| Chain | Residue |
| B | ASN524 |
| B | VAL526 |
| B | VAL529 |
| B | PRO531 |
| B | THR532 |
| B | GLY535 |
| B | THR536 |
| B | HOH868 |
| B | HOH1053 |
| B | HOH1121 |
| site_id | AE1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 712 |
| Chain | Residue |
| B | TYR429 |
| B | SER430 |
| B | ASN433 |
| B | GLN459 |
| B | HOH807 |
| B | HOH960 |
| B | HOH1022 |
| B | HOH1058 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS444 | |
| B | HIS444 | |
| Chain | Residue | Details |
| A | CYS477 | |
| B | CYS477 | |
| Chain | Residue | Details |
| A | ASP313 | |
| B | ASP339 | |
| B | PHE341 | |
| B | GLU343 | |
| B | PHE482 | |
| B | GLU491 | |
| A | ASP337 | |
| A | ASP339 | |
| A | PHE341 | |
| A | GLU343 | |
| A | PHE482 | |
| A | GLU491 | |
| B | ASP313 | |
| B | ASP337 | |
