6I7H
Crystal structure of dimeric FICD mutant K256S
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 501 |
| Chain | Residue |
| A | HOH601 |
| A | HOH606 |
| A | HOH641 |
| A | HOH700 |
| A | HOH734 |
| A | HOH740 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 135 |
| Details | Domain: {"description":"Fido","evidences":[{"source":"PROSITE-ProRule","id":"PRU00791","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Motif: {"description":"Inhibitory (S/T)XXXE(G/N) motif","evidences":[{"source":"PubMed","id":"22266942","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"22266942","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25435325","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U07","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25435325","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U07","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25435325","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U07","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for autoinhibition of adenylyltransferase activity","evidences":[{"source":"PubMed","id":"22266942","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25435325","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"O-AMP-threonine; by autocatalysis","evidences":[{"source":"PubMed","id":"25601083","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25601083","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
