Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0005046 | molecular_function | KDEL sequence binding |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005801 | cellular_component | cis-Golgi network |
| A | 0006621 | biological_process | protein retention in ER lumen |
| A | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0030663 | cellular_component | COPI-coated vesicle membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0035437 | biological_process | maintenance of protein localization in endoplasmic reticulum |
| A | 0046923 | molecular_function | ER retention sequence binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue OLC A 401 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 402 |
| Chain | Residue |
| A | PHE153 |
| A | PHE195 |
| A | OLC403 |
| A | OLC411 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue OLC A 403 |
| Chain | Residue |
| A | TYR198 |
| A | OLC401 |
| A | OLC402 |
| A | THR7 |
| A | ALA14 |
| A | PHE153 |
| A | PHE154 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue OLC A 404 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue OLC A 405 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue OLC A 406 |
| Chain | Residue |
| A | ILE56 |
| A | SER57 |
| A | TYR59 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue OLC A 407 |
| Chain | Residue |
| A | PHE97 |
| A | VAL109 |
| A | ASN110 |
| A | HIS111 |
| A | TYR125 |
| A | SER128 |
| A | OLC408 |
| A | OLC409 |
| A | OLC410 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue OLC A 408 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 409 |
| Chain | Residue |
| A | LEU108 |
| A | ASN110 |
| A | PHE113 |
| A | OLC407 |
| A | HOH517 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 410 |
| Chain | Residue |
| A | VAL129 |
| A | LEU132 |
| A | PHE136 |
| A | LEU190 |
| A | OLC407 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 411 |
| Chain | Residue |
| A | VAL189 |
| A | OLC402 |
Functional Information from PROSITE/UniProt
| site_id | PS00014 |
| Number of Residues | 4 |
| Details | ER_TARGET Endoplasmic reticulum targeting sequence. KDEL |
| Chain | Residue | Details |
| B | LYS4-LEU7 | |
| site_id | PS00951 |
| Number of Residues | 18 |
| Details | ER_LUMEN_RECEPTOR_1 ER lumen protein retaining receptor signature 1. GISgKsQlLFaLVFttRY |
| Chain | Residue | Details |
| A | GLY31-TYR48 | |
| site_id | PS00952 |
| Number of Residues | 10 |
| Details | ER_LUMEN_RECEPTOR_2 ER lumen protein retaining receptor signature 2. LESVAILPQL |
| Chain | Residue | Details |
| A | LEU126-LEU135 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"30846601","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 131 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"30846601","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"30846601","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Region: {"description":"Interaction with the K-D-E-L motif on target proteins","evidences":[{"source":"PubMed","id":"30846601","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for recycling of cargo proteins with the sequence motif K-D-E-L from the Golgi to the endoplasmic reticulum","evidences":[{"source":"PubMed","id":"30846601","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Site: {"description":"Interaction with the K-D-E-L motif on target proteins","evidences":[{"source":"PubMed","id":"30846601","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for recycling of cargo proteins with the sequence motif K-D-E-L from the Golgi to the endoplasmic reticulum","evidences":[{"source":"UniProtKB","id":"P24390","evidenceCode":"ECO:0000250"}]} |
