6I3S

Crystal structure of MDM2 in complex with compound 13.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue H28 A 201

Chain	Residue
A	LEU54
A	HOH315
A	HOH320
A	GLY58
A	ILE61
A	MET62
A	PHE86
A	VAL93
A	HIS96
A	ILE99
A	TYR100

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site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 202

Chain	Residue
A	ILE19
A	HIS96
A	TYR100
A	HOH311

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site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 A 203

Chain	Residue
A	GLN18
A	LYS94
A	GLU95
A	HIS96
A	ARG97
A	LYS98
A	HOH317

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site_id	AC4
Number of Residues	8
Details	binding site for residue SO4 A 204

Chain	Residue
A	ILE19
A	PRO20
A	ALA21
A	LYS51
A	LYS51
A	HOH313
A	HOH330
A	HOH336

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