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6I2N

Helical RNA-bound Hantaan virus nucleocapsid

Functional Information from GO Data
ChainGOidnamespacecontents
D0003723molecular_functionRNA binding
D0004518molecular_functionnuclease activity
D0004519molecular_functionendonuclease activity
D0016787molecular_functionhydrolase activity
D0019013cellular_componentviral nucleocapsid
D0019028cellular_componentviral capsid
D0019029cellular_componenthelical viral capsid
D0030430cellular_componenthost cell cytoplasm
D0033668biological_processsymbiont-mediated suppression of host apoptosis
D0044177cellular_componenthost cell Golgi apparatus
D0044220cellular_componenthost cell perinuclear region of cytoplasm
D0044423cellular_componentvirion component
D0052150biological_processsymbiont-mediated perturbation of host apoptosis
D1990904cellular_componentribonucleoprotein complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues25
DetailsRegion: {"description":"Homomultimerization","evidences":[{"source":"PubMed","id":"12502810","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues25
DetailsRegion: {"description":"Interaction with host RPS19","evidences":[{"source":"UniProtKB","id":"Q89462","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues42
DetailsRegion: {"description":"Viral RNA-binding","evidences":[{"source":"PubMed","id":"11884555","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16014963","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues3
DetailsRegion: {"description":"Interaction with host UBE2I/UBC9","evidences":[{"source":"PubMed","id":"12573574","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues56
DetailsRegion: {"description":"Interaction with host DAXX","evidences":[{"source":"UniProtKB","id":"P27313","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues48
DetailsRegion: {"description":"Homomultimerization","evidences":[{"source":"UniProtKB","id":"Q88918","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues3
DetailsMotif: {"description":"YxxL","evidences":[{"source":"PubMed","id":"31091447","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues2
DetailsSite: {"description":"Important for the endonuclease activity","evidences":[{"source":"UniProtKB","id":"Q89462","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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