Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 401 |
| Chain | Residue |
| A | GLY178 |
| A | TYR182 |
| A | VAL287 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | ASN205 |
| A | ASN229 |
| A | 5DD418 |
| A | 9O9419 |
| A | HOH551 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | SER223 |
| A | LEU226 |
| A | LEU226 |
| A | HOH546 |
| A | HOH546 |
| A | SER223 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | ALA278 |
| A | ALA278 |
| A | LEU279 |
| A | LEU279 |
| A | ARG280 |
| A | ARG280 |
| A | EDO404 |
| A | EDO405 |
| A | HOH529 |
| A | HOH529 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | TYR220 |
| A | ARG228 |
| A | ARG228 |
| A | PHE232 |
| A | EDO413 |
| A | EDO416 |
| A | HOH549 |
| A | HOH563 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | THR216 |
| A | LEU217 |
| A | ARG264 |
| A | LYS295 |
| A | HOH543 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | LYS295 |
| A | SER297 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | LEU250 |
| A | HOH530 |
| A | HOH591 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 411 |
| Chain | Residue |
| A | THR190 |
| A | GLN273 |
| A | CYS294 |
| A | TYR300 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 412 |
| Chain | Residue |
| A | LYS186 |
| A | THR257 |
| A | GLN273 |
| A | PHE304 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 413 |
| Chain | Residue |
| A | TYR220 |
| A | ASN229 |
| A | ARG231 |
| A | LYS265 |
| A | EDO407 |
| A | EDO416 |
| A | PEG417 |
| A | HOH505 |
| A | HOH532 |
| A | HOH563 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 414 |
| Chain | Residue |
| A | ASP266 |
| A | EDO415 |
| A | HOH506 |
| A | HOH509 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 415 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 416 |
| Chain | Residue |
| A | ARG228 |
| A | ASN229 |
| A | ARG231 |
| A | PHE232 |
| A | EDO407 |
| A | EDO413 |
| A | PEG417 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 417 |
| Chain | Residue |
| A | ARG231 |
| A | PHE232 |
| A | GLN234 |
| A | GLN234 |
| A | TYR263 |
| A | ARG264 |
| A | EDO413 |
| A | EDO416 |
| site_id | AD7 |
| Number of Residues | 23 |
| Details | binding site for residue 5DD A 418 |
| Chain | Residue |
| A | HOH519 |
| A | HOH536 |
| A | HOH547 |
| A | HOH551 |
| A | VAL196 |
| A | SER198 |
| A | ASN205 |
| A | ASN229 |
| A | CYS230 |
| A | ARG231 |
| A | LEU233 |
| A | GLN234 |
| A | VAL243 |
| A | VAL246 |
| A | LEU250 |
| A | ASN262 |
| A | ASN272 |
| A | TYR289 |
| A | GLY291 |
| A | GLN293 |
| A | CL402 |
| A | 9O9419 |
| A | HOH514 |
| site_id | AD8 |
| Number of Residues | 24 |
| Details | binding site for residue 9O9 A 419 |
| Chain | Residue |
| A | VAL196 |
| A | SER198 |
| A | ASN205 |
| A | ASN229 |
| A | CYS230 |
| A | ARG231 |
| A | GLN234 |
| A | VAL243 |
| A | ARG247 |
| A | LEU250 |
| A | ASN262 |
| A | ASN272 |
| A | LEU274 |
| A | TYR289 |
| A | LEU290 |
| A | GLY291 |
| A | GLN293 |
| A | CL402 |
| A | 5DD418 |
| A | HOH514 |
| A | HOH519 |
| A | HOH536 |
| A | HOH547 |
| A | HOH551 |
| site_id | AD9 |
| Number of Residues | 13 |
| Details | binding site for residues EDO A 404 and EDO A 405 |
| Chain | Residue |
| A | TYR182 |
| A | TYR182 |
| A | SER183 |
| A | SER183 |
| A | LEU184 |
| A | LEU184 |
| A | ASP255 |
| A | ASP255 |
| A | ALA277 |
| A | EDO406 |
| A | EDO406 |
| A | HOH517 |
| A | HOH529 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for residues EDO A 404 and EDO A 405 |
| Chain | Residue |
| A | TYR182 |
| A | TYR182 |
| A | SER183 |
| A | SER183 |
| A | LEU184 |
| A | LEU184 |
| A | ASP255 |
| A | ASP255 |
| A | ALA277 |
| A | EDO406 |
| A | EDO406 |
| A | HOH517 |
| A | HOH529 |
