Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6HUM

Structure of the photosynthetic complex I from Thermosynechococcus elongatus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003954	molecular_function	NADH dehydrogenase activity
A	0009060	biological_process	aerobic respiration
A	0009579	cellular_component	thylakoid
A	0016020	cellular_component	membrane
A	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
A	0019684	biological_process	photosynthesis, light reaction
A	0031676	cellular_component	plasma membrane-derived thylakoid membrane
A	0042651	cellular_component	thylakoid membrane
A	0048038	molecular_function	quinone binding
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0009579	cellular_component	thylakoid
B	0016020	cellular_component	membrane
B	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
B	0019684	biological_process	photosynthesis, light reaction
B	0031676	cellular_component	plasma membrane-derived thylakoid membrane
B	0042651	cellular_component	thylakoid membrane
B	0042773	biological_process	ATP synthesis coupled electron transport
B	0048038	molecular_function	quinone binding
B	1902600	biological_process	proton transmembrane transport
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0009579	cellular_component	thylakoid
C	0016020	cellular_component	membrane
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
C	0019684	biological_process	photosynthesis, light reaction
C	0030964	cellular_component	NADH dehydrogenase complex
C	0031676	cellular_component	plasma membrane-derived thylakoid membrane
C	0042651	cellular_component	thylakoid membrane
C	0048038	molecular_function	quinone binding
C	1902600	biological_process	proton transmembrane transport
D	0003954	molecular_function	NADH dehydrogenase activity
D	0005515	molecular_function	protein binding
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0009060	biological_process	aerobic respiration
D	0009579	cellular_component	thylakoid
D	0015990	biological_process	electron transport coupled proton transport
D	0016020	cellular_component	membrane
D	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
D	0031676	cellular_component	plasma membrane-derived thylakoid membrane
D	0042651	cellular_component	thylakoid membrane
D	0042773	biological_process	ATP synthesis coupled electron transport
D	0048038	molecular_function	quinone binding
D	0048039	molecular_function	ubiquinone binding
E	0009579	cellular_component	thylakoid
E	0016020	cellular_component	membrane
E	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
E	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
E	0019684	biological_process	photosynthesis, light reaction
E	0030964	cellular_component	NADH dehydrogenase complex
E	0031676	cellular_component	plasma membrane-derived thylakoid membrane
E	0042651	cellular_component	thylakoid membrane
E	0042773	biological_process	ATP synthesis coupled electron transport
E	0048038	molecular_function	quinone binding
F	0003954	molecular_function	NADH dehydrogenase activity
F	0005515	molecular_function	protein binding
F	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
F	0012505	cellular_component	endomembrane system
F	0015990	biological_process	electron transport coupled proton transport
F	0016020	cellular_component	membrane
F	0042773	biological_process	ATP synthesis coupled electron transport
F	0048038	molecular_function	quinone binding
G	0005886	cellular_component	plasma membrane
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0048038	molecular_function	quinone binding
G	1902495	cellular_component	transmembrane transporter complex
G	1902600	biological_process	proton transmembrane transport
H	0009579	cellular_component	thylakoid
H	0016020	cellular_component	membrane
H	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
H	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
H	0019684	biological_process	photosynthesis, light reaction
H	0031676	cellular_component	plasma membrane-derived thylakoid membrane
H	0042651	cellular_component	thylakoid membrane
H	0048038	molecular_function	quinone binding
H	0051287	molecular_function	NAD binding
I	0005506	molecular_function	iron ion binding
I	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
I	0009579	cellular_component	thylakoid
I	0016020	cellular_component	membrane
I	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
I	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
I	0019684	biological_process	photosynthesis, light reaction
I	0031676	cellular_component	plasma membrane-derived thylakoid membrane
I	0042651	cellular_component	thylakoid membrane
I	0046872	molecular_function	metal ion binding
I	0048038	molecular_function	quinone binding
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
I	1902600	biological_process	proton transmembrane transport
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0009579	cellular_component	thylakoid
J	0016020	cellular_component	membrane
J	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
J	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
J	0019684	biological_process	photosynthesis, light reaction
J	0031676	cellular_component	plasma membrane-derived thylakoid membrane
J	0042651	cellular_component	thylakoid membrane
J	0048038	molecular_function	quinone binding
J	1902600	biological_process	proton transmembrane transport
K	0005506	molecular_function	iron ion binding
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0009060	biological_process	aerobic respiration
K	0009579	cellular_component	thylakoid
K	0015990	biological_process	electron transport coupled proton transport
K	0016020	cellular_component	membrane
K	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
K	0019684	biological_process	photosynthesis, light reaction
K	0031676	cellular_component	plasma membrane-derived thylakoid membrane
K	0042651	cellular_component	thylakoid membrane
K	0045271	cellular_component	respiratory chain complex I
K	0046872	molecular_function	metal ion binding
K	0048038	molecular_function	quinone binding
K	0051536	molecular_function	iron-sulfur cluster binding
K	0051539	molecular_function	4 iron, 4 sulfur cluster binding
L	0009579	cellular_component	thylakoid
L	0016020	cellular_component	membrane
L	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
L	0031676	cellular_component	plasma membrane-derived thylakoid membrane
L	0042651	cellular_component	thylakoid membrane
L	0048038	molecular_function	quinone binding
M	0009579	cellular_component	thylakoid
M	0016020	cellular_component	membrane
M	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
M	0031676	cellular_component	plasma membrane-derived thylakoid membrane
M	0042651	cellular_component	thylakoid membrane
M	0048038	molecular_function	quinone binding
N	0009579	cellular_component	thylakoid
N	0016020	cellular_component	membrane
N	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
N	0031676	cellular_component	plasma membrane-derived thylakoid membrane
N	0042651	cellular_component	thylakoid membrane
N	0048038	molecular_function	quinone binding
O	0005886	cellular_component	plasma membrane
O	0009579	cellular_component	thylakoid
O	0016020	cellular_component	membrane
O	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
O	0031676	cellular_component	plasma membrane-derived thylakoid membrane
O	0042651	cellular_component	thylakoid membrane
O	0048038	molecular_function	quinone binding
S	0009767	biological_process	photosynthetic electron transport chain

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue BCR D 601

Chain	Residue
D	ALA468
D	VAL472
D	PRO473
D	ILE475
F	LEU20

site_id	AC2
Number of Residues	10
Details	binding site for residue LMG D 602

Chain	Residue
F	LEU20
F	GLY23
F	LEU26
F	ILE27
F	GLY120
F	TYR127
D	LYS373
D	PHE376
D	ALA377
D	MET392

site_id	AC3
Number of Residues	7
Details	binding site for residue SF4 I 201

Chain	Residue
I	CYS73
I	CYS103
I	ILE104
I	PHE105
I	CYS106
I	ALA107
I	CYS109

site_id	AC4
Number of Residues	6
Details	binding site for residue SF4 I 202

Chain	Residue
I	PHE58
I	CYS63
I	ILE64
I	CYS66
I	CYS69
I	CYS113

site_id	AC5
Number of Residues	10
Details	binding site for residue SF4 K 501

Chain	Residue
H	ARG69
K	ALA51
K	CYS52
K	CYS53
K	THR89
K	GLY115
K	ALA116
K	CYS117
K	CYS148
K	PRO149

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	27
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGIGLMGITVaYlmylkgtpspq.......AIAK

Chain	Residue	Details
F	VAL541-LYS567

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACEvCVrVCP

Chain	Residue	Details
I	CYS63-PRO74
I	CYS103-PRO114

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGmEKIaEnR

Chain	Residue	Details
H	LEU47-ARG58

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREsyDMFgivyegHpnlKrIL

Chain	Residue	Details
J	GLU121-LEU142

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GILApLaDGLKLIfKE

Chain	Residue	Details
A	GLY72-GLU87

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLPEAEeeLVa.G

Chain	Residue	Details
A	PRO231-GLY244

site_id	PS01036
Number of Residues	15
Details	HSP70_3 Heat shock hsp70 proteins family signature 3. YgLsGGhTQLPaIaQ

Chain	Residue	Details
B	TYR185-GLN199

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GvDKLIPVDVYlPgCPP

Chain	Residue	Details
K	GLY134-PRO150

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
L	LEU8-VAL28
B	MET302-THR322
B	LEU330-PHE350
B	LEU374-GLY394
B	ILE396-LEU416
B	VAL462-PHE482
L	ALA45-ILE65
K	CYS117
K	CYS148
I	CYS103
I	CYS106
I	CYS109
I	CYS113
B	TRP274-LEU294

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)