6HT7

Crystal structure of the WT human mitochondrial chaperonin (ADP:BeF3)14 complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0001649	biological_process	osteoblast differentiation
1	0003723	molecular_function	RNA binding
1	0005515	molecular_function	protein binding
1	0005524	molecular_function	ATP binding
1	0005739	cellular_component	mitochondrion
1	0005759	cellular_component	mitochondrial matrix
1	0006457	biological_process	protein folding
1	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
1	0006986	biological_process	response to unfolded protein
1	0016020	cellular_component	membrane
1	0044183	molecular_function	protein folding chaperone
1	0046872	molecular_function	metal ion binding
1	0051082	molecular_function	unfolded protein binding
1	0051085	biological_process	chaperone cofactor-dependent protein refolding
1	0051087	molecular_function	protein-folding chaperone binding
1	0070062	cellular_component	extracellular exosome
2	0001649	biological_process	osteoblast differentiation
2	0003723	molecular_function	RNA binding
2	0005515	molecular_function	protein binding
2	0005524	molecular_function	ATP binding
2	0005739	cellular_component	mitochondrion
2	0005759	cellular_component	mitochondrial matrix
2	0006457	biological_process	protein folding
2	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
2	0006986	biological_process	response to unfolded protein
2	0016020	cellular_component	membrane
2	0044183	molecular_function	protein folding chaperone
2	0046872	molecular_function	metal ion binding
2	0051082	molecular_function	unfolded protein binding
2	0051085	biological_process	chaperone cofactor-dependent protein refolding
2	0051087	molecular_function	protein-folding chaperone binding
2	0070062	cellular_component	extracellular exosome
A	0001530	molecular_function	lipopolysaccharide binding
A	0002039	molecular_function	p53 binding
A	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
A	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
A	0003688	molecular_function	DNA replication origin binding
A	0003697	molecular_function	single-stranded DNA binding
A	0003723	molecular_function	RNA binding
A	0003725	molecular_function	double-stranded RNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005759	cellular_component	mitochondrial matrix
A	0005769	cellular_component	early endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005905	cellular_component	clathrin-coated pit
A	0006457	biological_process	protein folding
A	0006458	biological_process	'de novo' protein folding
A	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
A	0006986	biological_process	response to unfolded protein
A	0008035	molecular_function	high-density lipoprotein particle binding
A	0008637	biological_process	apoptotic mitochondrial changes
A	0009409	biological_process	response to cold
A	0009986	cellular_component	cell surface
A	0016020	cellular_component	membrane
A	0016853	molecular_function	isomerase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0019899	molecular_function	enzyme binding
A	0030135	cellular_component	coated vesicle
A	0030141	cellular_component	secretory granule
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032727	biological_process	positive regulation of interferon-alpha production
A	0032729	biological_process	positive regulation of type II interferon production
A	0032733	biological_process	positive regulation of interleukin-10 production
A	0032735	biological_process	positive regulation of interleukin-12 production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0032991	cellular_component	protein-containing complex
A	0034185	molecular_function	apolipoprotein binding
A	0034186	molecular_function	apolipoprotein A-I binding
A	0034514	biological_process	mitochondrial unfolded protein response
A	0042026	biological_process	protein refolding
A	0042100	biological_process	B cell proliferation
A	0042110	biological_process	T cell activation
A	0042113	biological_process	B cell activation
A	0043032	biological_process	positive regulation of macrophage activation
A	0043065	biological_process	positive regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0044406	biological_process	adhesion of symbiont to host
A	0045041	biological_process	protein import into mitochondrial intermembrane space
A	0046696	cellular_component	lipopolysaccharide receptor complex
A	0048291	biological_process	isotype switching to IgG isotypes
A	0050821	biological_process	protein stabilization
A	0050870	biological_process	positive regulation of T cell activation
A	0051082	molecular_function	unfolded protein binding
A	0051087	molecular_function	protein-folding chaperone binding
A	0051131	biological_process	chaperone-mediated protein complex assembly
A	0051604	biological_process	protein maturation
A	0051702	biological_process	biological process involved in interaction with symbiont
A	0070062	cellular_component	extracellular exosome
A	0097225	cellular_component	sperm midpiece
A	0097524	cellular_component	sperm plasma membrane
A	0098761	biological_process	cellular response to interleukin-7
A	0140494	cellular_component	migrasome
A	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0001530	molecular_function	lipopolysaccharide binding
B	0002039	molecular_function	p53 binding
B	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
B	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
B	0003688	molecular_function	DNA replication origin binding
B	0003697	molecular_function	single-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0003725	molecular_function	double-stranded RNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005615	cellular_component	extracellular space
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005759	cellular_component	mitochondrial matrix
B	0005769	cellular_component	early endosome
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005905	cellular_component	clathrin-coated pit
B	0006457	biological_process	protein folding
B	0006458	biological_process	'de novo' protein folding
B	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
B	0006986	biological_process	response to unfolded protein
B	0008035	molecular_function	high-density lipoprotein particle binding
B	0008637	biological_process	apoptotic mitochondrial changes
B	0009409	biological_process	response to cold
B	0009986	cellular_component	cell surface
B	0016020	cellular_component	membrane
B	0016853	molecular_function	isomerase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0019899	molecular_function	enzyme binding
B	0030135	cellular_component	coated vesicle
B	0030141	cellular_component	secretory granule
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032727	biological_process	positive regulation of interferon-alpha production
B	0032729	biological_process	positive regulation of type II interferon production
B	0032733	biological_process	positive regulation of interleukin-10 production
B	0032735	biological_process	positive regulation of interleukin-12 production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0032991	cellular_component	protein-containing complex
B	0034185	molecular_function	apolipoprotein binding
B	0034186	molecular_function	apolipoprotein A-I binding
B	0034514	biological_process	mitochondrial unfolded protein response
B	0042026	biological_process	protein refolding
B	0042100	biological_process	B cell proliferation
B	0042110	biological_process	T cell activation
B	0042113	biological_process	B cell activation
B	0043032	biological_process	positive regulation of macrophage activation
B	0043065	biological_process	positive regulation of apoptotic process
B	0043066	biological_process	negative regulation of apoptotic process
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0044406	biological_process	adhesion of symbiont to host
B	0045041	biological_process	protein import into mitochondrial intermembrane space
B	0046696	cellular_component	lipopolysaccharide receptor complex
B	0048291	biological_process	isotype switching to IgG isotypes
B	0050821	biological_process	protein stabilization
B	0050870	biological_process	positive regulation of T cell activation
B	0051082	molecular_function	unfolded protein binding
B	0051087	molecular_function	protein-folding chaperone binding
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0051604	biological_process	protein maturation
B	0051702	biological_process	biological process involved in interaction with symbiont
B	0070062	cellular_component	extracellular exosome
B	0097225	cellular_component	sperm midpiece
B	0097524	cellular_component	sperm plasma membrane
B	0098761	biological_process	cellular response to interleukin-7
B	0140494	cellular_component	migrasome
B	0140662	molecular_function	ATP-dependent protein folding chaperone
C	0001530	molecular_function	lipopolysaccharide binding
C	0002039	molecular_function	p53 binding
C	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
C	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
C	0003688	molecular_function	DNA replication origin binding
C	0003697	molecular_function	single-stranded DNA binding
C	0003723	molecular_function	RNA binding
C	0003725	molecular_function	double-stranded RNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005759	cellular_component	mitochondrial matrix
C	0005769	cellular_component	early endosome
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0005905	cellular_component	clathrin-coated pit
C	0006457	biological_process	protein folding
C	0006458	biological_process	'de novo' protein folding
C	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
C	0006986	biological_process	response to unfolded protein
C	0008035	molecular_function	high-density lipoprotein particle binding
C	0008637	biological_process	apoptotic mitochondrial changes
C	0009409	biological_process	response to cold
C	0009986	cellular_component	cell surface
C	0016020	cellular_component	membrane
C	0016853	molecular_function	isomerase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0019899	molecular_function	enzyme binding
C	0030135	cellular_component	coated vesicle
C	0030141	cellular_component	secretory granule
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032727	biological_process	positive regulation of interferon-alpha production
C	0032729	biological_process	positive regulation of type II interferon production
C	0032733	biological_process	positive regulation of interleukin-10 production
C	0032735	biological_process	positive regulation of interleukin-12 production
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0032991	cellular_component	protein-containing complex
C	0034185	molecular_function	apolipoprotein binding
C	0034186	molecular_function	apolipoprotein A-I binding
C	0034514	biological_process	mitochondrial unfolded protein response
C	0042026	biological_process	protein refolding
C	0042100	biological_process	B cell proliferation
C	0042110	biological_process	T cell activation
C	0042113	biological_process	B cell activation
C	0043032	biological_process	positive regulation of macrophage activation
C	0043065	biological_process	positive regulation of apoptotic process
C	0043066	biological_process	negative regulation of apoptotic process
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0044406	biological_process	adhesion of symbiont to host
C	0045041	biological_process	protein import into mitochondrial intermembrane space
C	0046696	cellular_component	lipopolysaccharide receptor complex
C	0048291	biological_process	isotype switching to IgG isotypes
C	0050821	biological_process	protein stabilization
C	0050870	biological_process	positive regulation of T cell activation
C	0051082	molecular_function	unfolded protein binding
C	0051087	molecular_function	protein-folding chaperone binding
C	0051131	biological_process	chaperone-mediated protein complex assembly
C	0051604	biological_process	protein maturation
C	0051702	biological_process	biological process involved in interaction with symbiont
C	0070062	cellular_component	extracellular exosome
C	0097225	cellular_component	sperm midpiece
C	0097524	cellular_component	sperm plasma membrane
C	0098761	biological_process	cellular response to interleukin-7
C	0140494	cellular_component	migrasome
C	0140662	molecular_function	ATP-dependent protein folding chaperone
D	0001530	molecular_function	lipopolysaccharide binding
D	0002039	molecular_function	p53 binding
D	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
D	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
D	0003688	molecular_function	DNA replication origin binding
D	0003697	molecular_function	single-stranded DNA binding
D	0003723	molecular_function	RNA binding
D	0003725	molecular_function	double-stranded RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005615	cellular_component	extracellular space
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005759	cellular_component	mitochondrial matrix
D	0005769	cellular_component	early endosome
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0005905	cellular_component	clathrin-coated pit
D	0006457	biological_process	protein folding
D	0006458	biological_process	'de novo' protein folding
D	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
D	0006986	biological_process	response to unfolded protein
D	0008035	molecular_function	high-density lipoprotein particle binding
D	0008637	biological_process	apoptotic mitochondrial changes
D	0009409	biological_process	response to cold
D	0009986	cellular_component	cell surface
D	0016020	cellular_component	membrane
D	0016853	molecular_function	isomerase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0019899	molecular_function	enzyme binding
D	0030135	cellular_component	coated vesicle
D	0030141	cellular_component	secretory granule
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0032727	biological_process	positive regulation of interferon-alpha production
D	0032729	biological_process	positive regulation of type II interferon production
D	0032733	biological_process	positive regulation of interleukin-10 production
D	0032735	biological_process	positive regulation of interleukin-12 production
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0032991	cellular_component	protein-containing complex
D	0034185	molecular_function	apolipoprotein binding
D	0034186	molecular_function	apolipoprotein A-I binding
D	0034514	biological_process	mitochondrial unfolded protein response
D	0042026	biological_process	protein refolding
D	0042100	biological_process	B cell proliferation
D	0042110	biological_process	T cell activation
D	0042113	biological_process	B cell activation
D	0043032	biological_process	positive regulation of macrophage activation
D	0043065	biological_process	positive regulation of apoptotic process
D	0043066	biological_process	negative regulation of apoptotic process
D	0043231	cellular_component	intracellular membrane-bounded organelle
D	0044406	biological_process	adhesion of symbiont to host
D	0045041	biological_process	protein import into mitochondrial intermembrane space
D	0046696	cellular_component	lipopolysaccharide receptor complex
D	0048291	biological_process	isotype switching to IgG isotypes
D	0050821	biological_process	protein stabilization
D	0050870	biological_process	positive regulation of T cell activation
D	0051082	molecular_function	unfolded protein binding
D	0051087	molecular_function	protein-folding chaperone binding
D	0051131	biological_process	chaperone-mediated protein complex assembly
D	0051604	biological_process	protein maturation
D	0051702	biological_process	biological process involved in interaction with symbiont
D	0070062	cellular_component	extracellular exosome
D	0097225	cellular_component	sperm midpiece
D	0097524	cellular_component	sperm plasma membrane
D	0098761	biological_process	cellular response to interleukin-7
D	0140494	cellular_component	migrasome
D	0140662	molecular_function	ATP-dependent protein folding chaperone
E	0001530	molecular_function	lipopolysaccharide binding
E	0002039	molecular_function	p53 binding
E	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
E	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
E	0003688	molecular_function	DNA replication origin binding
E	0003697	molecular_function	single-stranded DNA binding
E	0003723	molecular_function	RNA binding
E	0003725	molecular_function	double-stranded RNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005615	cellular_component	extracellular space
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005759	cellular_component	mitochondrial matrix
E	0005769	cellular_component	early endosome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005905	cellular_component	clathrin-coated pit
E	0006457	biological_process	protein folding
E	0006458	biological_process	'de novo' protein folding
E	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
E	0006986	biological_process	response to unfolded protein
E	0008035	molecular_function	high-density lipoprotein particle binding
E	0008637	biological_process	apoptotic mitochondrial changes
E	0009409	biological_process	response to cold
E	0009986	cellular_component	cell surface
E	0016020	cellular_component	membrane
E	0016853	molecular_function	isomerase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0019899	molecular_function	enzyme binding
E	0030135	cellular_component	coated vesicle
E	0030141	cellular_component	secretory granule
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0032727	biological_process	positive regulation of interferon-alpha production
E	0032729	biological_process	positive regulation of type II interferon production
E	0032733	biological_process	positive regulation of interleukin-10 production
E	0032735	biological_process	positive regulation of interleukin-12 production
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0032991	cellular_component	protein-containing complex
E	0034185	molecular_function	apolipoprotein binding
E	0034186	molecular_function	apolipoprotein A-I binding
E	0034514	biological_process	mitochondrial unfolded protein response
E	0042026	biological_process	protein refolding
E	0042100	biological_process	B cell proliferation
E	0042110	biological_process	T cell activation
E	0042113	biological_process	B cell activation
E	0043032	biological_process	positive regulation of macrophage activation
E	0043065	biological_process	positive regulation of apoptotic process
E	0043066	biological_process	negative regulation of apoptotic process
E	0043231	cellular_component	intracellular membrane-bounded organelle
E	0044406	biological_process	adhesion of symbiont to host
E	0045041	biological_process	protein import into mitochondrial intermembrane space
E	0046696	cellular_component	lipopolysaccharide receptor complex
E	0048291	biological_process	isotype switching to IgG isotypes
E	0050821	biological_process	protein stabilization
E	0050870	biological_process	positive regulation of T cell activation
E	0051082	molecular_function	unfolded protein binding
E	0051087	molecular_function	protein-folding chaperone binding
E	0051131	biological_process	chaperone-mediated protein complex assembly
E	0051604	biological_process	protein maturation
E	0051702	biological_process	biological process involved in interaction with symbiont
E	0070062	cellular_component	extracellular exosome
E	0097225	cellular_component	sperm midpiece
E	0097524	cellular_component	sperm plasma membrane
E	0098761	biological_process	cellular response to interleukin-7
E	0140494	cellular_component	migrasome
E	0140662	molecular_function	ATP-dependent protein folding chaperone
F	0001530	molecular_function	lipopolysaccharide binding
F	0002039	molecular_function	p53 binding
F	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
F	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
F	0003688	molecular_function	DNA replication origin binding
F	0003697	molecular_function	single-stranded DNA binding
F	0003723	molecular_function	RNA binding
F	0003725	molecular_function	double-stranded RNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005615	cellular_component	extracellular space
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005759	cellular_component	mitochondrial matrix
F	0005769	cellular_component	early endosome
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0005905	cellular_component	clathrin-coated pit
F	0006457	biological_process	protein folding
F	0006458	biological_process	'de novo' protein folding
F	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
F	0006986	biological_process	response to unfolded protein
F	0008035	molecular_function	high-density lipoprotein particle binding
F	0008637	biological_process	apoptotic mitochondrial changes
F	0009409	biological_process	response to cold
F	0009986	cellular_component	cell surface
F	0016020	cellular_component	membrane
F	0016853	molecular_function	isomerase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0019899	molecular_function	enzyme binding
F	0030135	cellular_component	coated vesicle
F	0030141	cellular_component	secretory granule
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032727	biological_process	positive regulation of interferon-alpha production
F	0032729	biological_process	positive regulation of type II interferon production
F	0032733	biological_process	positive regulation of interleukin-10 production
F	0032735	biological_process	positive regulation of interleukin-12 production
F	0032755	biological_process	positive regulation of interleukin-6 production
F	0032991	cellular_component	protein-containing complex
F	0034185	molecular_function	apolipoprotein binding
F	0034186	molecular_function	apolipoprotein A-I binding
F	0034514	biological_process	mitochondrial unfolded protein response
F	0042026	biological_process	protein refolding
F	0042100	biological_process	B cell proliferation
F	0042110	biological_process	T cell activation
F	0042113	biological_process	B cell activation
F	0043032	biological_process	positive regulation of macrophage activation
F	0043065	biological_process	positive regulation of apoptotic process
F	0043066	biological_process	negative regulation of apoptotic process
F	0043231	cellular_component	intracellular membrane-bounded organelle
F	0044406	biological_process	adhesion of symbiont to host
F	0045041	biological_process	protein import into mitochondrial intermembrane space
F	0046696	cellular_component	lipopolysaccharide receptor complex
F	0048291	biological_process	isotype switching to IgG isotypes
F	0050821	biological_process	protein stabilization
F	0050870	biological_process	positive regulation of T cell activation
F	0051082	molecular_function	unfolded protein binding
F	0051087	molecular_function	protein-folding chaperone binding
F	0051131	biological_process	chaperone-mediated protein complex assembly
F	0051604	biological_process	protein maturation
F	0051702	biological_process	biological process involved in interaction with symbiont
F	0070062	cellular_component	extracellular exosome
F	0097225	cellular_component	sperm midpiece
F	0097524	cellular_component	sperm plasma membrane
F	0098761	biological_process	cellular response to interleukin-7
F	0140494	cellular_component	migrasome
F	0140662	molecular_function	ATP-dependent protein folding chaperone
G	0001530	molecular_function	lipopolysaccharide binding
G	0002039	molecular_function	p53 binding
G	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
G	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
G	0003688	molecular_function	DNA replication origin binding
G	0003697	molecular_function	single-stranded DNA binding
G	0003723	molecular_function	RNA binding
G	0003725	molecular_function	double-stranded RNA binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005615	cellular_component	extracellular space
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005759	cellular_component	mitochondrial matrix
G	0005769	cellular_component	early endosome
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0005905	cellular_component	clathrin-coated pit
G	0006457	biological_process	protein folding
G	0006458	biological_process	'de novo' protein folding
G	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
G	0006986	biological_process	response to unfolded protein
G	0008035	molecular_function	high-density lipoprotein particle binding
G	0008637	biological_process	apoptotic mitochondrial changes
G	0009409	biological_process	response to cold
G	0009986	cellular_component	cell surface
G	0016020	cellular_component	membrane
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019899	molecular_function	enzyme binding
G	0030135	cellular_component	coated vesicle
G	0030141	cellular_component	secretory granule
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032727	biological_process	positive regulation of interferon-alpha production
G	0032729	biological_process	positive regulation of type II interferon production
G	0032733	biological_process	positive regulation of interleukin-10 production
G	0032735	biological_process	positive regulation of interleukin-12 production
G	0032755	biological_process	positive regulation of interleukin-6 production
G	0032991	cellular_component	protein-containing complex
G	0034185	molecular_function	apolipoprotein binding
G	0034186	molecular_function	apolipoprotein A-I binding
G	0034514	biological_process	mitochondrial unfolded protein response
G	0042026	biological_process	protein refolding
G	0042100	biological_process	B cell proliferation
G	0042110	biological_process	T cell activation
G	0042113	biological_process	B cell activation
G	0043032	biological_process	positive regulation of macrophage activation
G	0043065	biological_process	positive regulation of apoptotic process
G	0043066	biological_process	negative regulation of apoptotic process
G	0043231	cellular_component	intracellular membrane-bounded organelle
G	0044406	biological_process	adhesion of symbiont to host
G	0045041	biological_process	protein import into mitochondrial intermembrane space
G	0046696	cellular_component	lipopolysaccharide receptor complex
G	0048291	biological_process	isotype switching to IgG isotypes
G	0050821	biological_process	protein stabilization
G	0050870	biological_process	positive regulation of T cell activation
G	0051082	molecular_function	unfolded protein binding
G	0051087	molecular_function	protein-folding chaperone binding
G	0051131	biological_process	chaperone-mediated protein complex assembly
G	0051604	biological_process	protein maturation
G	0051702	biological_process	biological process involved in interaction with symbiont
G	0070062	cellular_component	extracellular exosome
G	0097225	cellular_component	sperm midpiece
G	0097524	cellular_component	sperm plasma membrane
G	0098761	biological_process	cellular response to interleukin-7
G	0140494	cellular_component	migrasome
G	0140662	molecular_function	ATP-dependent protein folding chaperone
H	0001530	molecular_function	lipopolysaccharide binding
H	0002039	molecular_function	p53 binding
H	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
H	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
H	0003688	molecular_function	DNA replication origin binding
H	0003697	molecular_function	single-stranded DNA binding
H	0003723	molecular_function	RNA binding
H	0003725	molecular_function	double-stranded RNA binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005615	cellular_component	extracellular space
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005759	cellular_component	mitochondrial matrix
H	0005769	cellular_component	early endosome
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0005905	cellular_component	clathrin-coated pit
H	0006457	biological_process	protein folding
H	0006458	biological_process	'de novo' protein folding
H	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
H	0006986	biological_process	response to unfolded protein
H	0008035	molecular_function	high-density lipoprotein particle binding
H	0008637	biological_process	apoptotic mitochondrial changes
H	0009409	biological_process	response to cold
H	0009986	cellular_component	cell surface
H	0016020	cellular_component	membrane
H	0016853	molecular_function	isomerase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0019899	molecular_function	enzyme binding
H	0030135	cellular_component	coated vesicle
H	0030141	cellular_component	secretory granule
H	0031625	molecular_function	ubiquitin protein ligase binding
H	0032727	biological_process	positive regulation of interferon-alpha production
H	0032729	biological_process	positive regulation of type II interferon production
H	0032733	biological_process	positive regulation of interleukin-10 production
H	0032735	biological_process	positive regulation of interleukin-12 production
H	0032755	biological_process	positive regulation of interleukin-6 production
H	0032991	cellular_component	protein-containing complex
H	0034185	molecular_function	apolipoprotein binding
H	0034186	molecular_function	apolipoprotein A-I binding
H	0034514	biological_process	mitochondrial unfolded protein response
H	0042026	biological_process	protein refolding
H	0042100	biological_process	B cell proliferation
H	0042110	biological_process	T cell activation
H	0042113	biological_process	B cell activation
H	0043032	biological_process	positive regulation of macrophage activation
H	0043065	biological_process	positive regulation of apoptotic process
H	0043066	biological_process	negative regulation of apoptotic process
H	0043231	cellular_component	intracellular membrane-bounded organelle
H	0044406	biological_process	adhesion of symbiont to host
H	0045041	biological_process	protein import into mitochondrial intermembrane space
H	0046696	cellular_component	lipopolysaccharide receptor complex
H	0048291	biological_process	isotype switching to IgG isotypes
H	0050821	biological_process	protein stabilization
H	0050870	biological_process	positive regulation of T cell activation
H	0051082	molecular_function	unfolded protein binding
H	0051087	molecular_function	protein-folding chaperone binding
H	0051131	biological_process	chaperone-mediated protein complex assembly
H	0051604	biological_process	protein maturation
H	0051702	biological_process	biological process involved in interaction with symbiont
H	0070062	cellular_component	extracellular exosome
H	0097225	cellular_component	sperm midpiece
H	0097524	cellular_component	sperm plasma membrane
H	0098761	biological_process	cellular response to interleukin-7
H	0140494	cellular_component	migrasome
H	0140662	molecular_function	ATP-dependent protein folding chaperone
I	0001530	molecular_function	lipopolysaccharide binding
I	0002039	molecular_function	p53 binding
I	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
I	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
I	0003688	molecular_function	DNA replication origin binding
I	0003697	molecular_function	single-stranded DNA binding
I	0003723	molecular_function	RNA binding
I	0003725	molecular_function	double-stranded RNA binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005615	cellular_component	extracellular space
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005759	cellular_component	mitochondrial matrix
I	0005769	cellular_component	early endosome
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0005905	cellular_component	clathrin-coated pit
I	0006457	biological_process	protein folding
I	0006458	biological_process	'de novo' protein folding
I	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
I	0006986	biological_process	response to unfolded protein
I	0008035	molecular_function	high-density lipoprotein particle binding
I	0008637	biological_process	apoptotic mitochondrial changes
I	0009409	biological_process	response to cold
I	0009986	cellular_component	cell surface
I	0016020	cellular_component	membrane
I	0016853	molecular_function	isomerase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0019899	molecular_function	enzyme binding
I	0030135	cellular_component	coated vesicle
I	0030141	cellular_component	secretory granule
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0032727	biological_process	positive regulation of interferon-alpha production
I	0032729	biological_process	positive regulation of type II interferon production
I	0032733	biological_process	positive regulation of interleukin-10 production
I	0032735	biological_process	positive regulation of interleukin-12 production
I	0032755	biological_process	positive regulation of interleukin-6 production
I	0032991	cellular_component	protein-containing complex
I	0034185	molecular_function	apolipoprotein binding
I	0034186	molecular_function	apolipoprotein A-I binding
I	0034514	biological_process	mitochondrial unfolded protein response
I	0042026	biological_process	protein refolding
I	0042100	biological_process	B cell proliferation
I	0042110	biological_process	T cell activation
I	0042113	biological_process	B cell activation
I	0043032	biological_process	positive regulation of macrophage activation
I	0043065	biological_process	positive regulation of apoptotic process
I	0043066	biological_process	negative regulation of apoptotic process
I	0043231	cellular_component	intracellular membrane-bounded organelle
I	0044406	biological_process	adhesion of symbiont to host
I	0045041	biological_process	protein import into mitochondrial intermembrane space
I	0046696	cellular_component	lipopolysaccharide receptor complex
I	0048291	biological_process	isotype switching to IgG isotypes
I	0050821	biological_process	protein stabilization
I	0050870	biological_process	positive regulation of T cell activation
I	0051082	molecular_function	unfolded protein binding
I	0051087	molecular_function	protein-folding chaperone binding
I	0051131	biological_process	chaperone-mediated protein complex assembly
I	0051604	biological_process	protein maturation
I	0051702	biological_process	biological process involved in interaction with symbiont
I	0070062	cellular_component	extracellular exosome
I	0097225	cellular_component	sperm midpiece
I	0097524	cellular_component	sperm plasma membrane
I	0098761	biological_process	cellular response to interleukin-7
I	0140494	cellular_component	migrasome
I	0140662	molecular_function	ATP-dependent protein folding chaperone
J	0001530	molecular_function	lipopolysaccharide binding
J	0002039	molecular_function	p53 binding
J	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
J	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
J	0003688	molecular_function	DNA replication origin binding
J	0003697	molecular_function	single-stranded DNA binding
J	0003723	molecular_function	RNA binding
J	0003725	molecular_function	double-stranded RNA binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005615	cellular_component	extracellular space
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005759	cellular_component	mitochondrial matrix
J	0005769	cellular_component	early endosome
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0005905	cellular_component	clathrin-coated pit
J	0006457	biological_process	protein folding
J	0006458	biological_process	'de novo' protein folding
J	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
J	0006986	biological_process	response to unfolded protein
J	0008035	molecular_function	high-density lipoprotein particle binding
J	0008637	biological_process	apoptotic mitochondrial changes
J	0009409	biological_process	response to cold
J	0009986	cellular_component	cell surface
J	0016020	cellular_component	membrane
J	0016853	molecular_function	isomerase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019899	molecular_function	enzyme binding
J	0030135	cellular_component	coated vesicle
J	0030141	cellular_component	secretory granule
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032727	biological_process	positive regulation of interferon-alpha production
J	0032729	biological_process	positive regulation of type II interferon production
J	0032733	biological_process	positive regulation of interleukin-10 production
J	0032735	biological_process	positive regulation of interleukin-12 production
J	0032755	biological_process	positive regulation of interleukin-6 production
J	0032991	cellular_component	protein-containing complex
J	0034185	molecular_function	apolipoprotein binding
J	0034186	molecular_function	apolipoprotein A-I binding
J	0034514	biological_process	mitochondrial unfolded protein response
J	0042026	biological_process	protein refolding
J	0042100	biological_process	B cell proliferation
J	0042110	biological_process	T cell activation
J	0042113	biological_process	B cell activation
J	0043032	biological_process	positive regulation of macrophage activation
J	0043065	biological_process	positive regulation of apoptotic process
J	0043066	biological_process	negative regulation of apoptotic process
J	0043231	cellular_component	intracellular membrane-bounded organelle
J	0044406	biological_process	adhesion of symbiont to host
J	0045041	biological_process	protein import into mitochondrial intermembrane space
J	0046696	cellular_component	lipopolysaccharide receptor complex
J	0048291	biological_process	isotype switching to IgG isotypes
J	0050821	biological_process	protein stabilization
J	0050870	biological_process	positive regulation of T cell activation
J	0051082	molecular_function	unfolded protein binding
J	0051087	molecular_function	protein-folding chaperone binding
J	0051131	biological_process	chaperone-mediated protein complex assembly
J	0051604	biological_process	protein maturation
J	0051702	biological_process	biological process involved in interaction with symbiont
J	0070062	cellular_component	extracellular exosome
J	0097225	cellular_component	sperm midpiece
J	0097524	cellular_component	sperm plasma membrane
J	0098761	biological_process	cellular response to interleukin-7
J	0140494	cellular_component	migrasome
J	0140662	molecular_function	ATP-dependent protein folding chaperone
K	0001530	molecular_function	lipopolysaccharide binding
K	0002039	molecular_function	p53 binding
K	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
K	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
K	0003688	molecular_function	DNA replication origin binding
K	0003697	molecular_function	single-stranded DNA binding
K	0003723	molecular_function	RNA binding
K	0003725	molecular_function	double-stranded RNA binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005615	cellular_component	extracellular space
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005759	cellular_component	mitochondrial matrix
K	0005769	cellular_component	early endosome
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0005905	cellular_component	clathrin-coated pit
K	0006457	biological_process	protein folding
K	0006458	biological_process	'de novo' protein folding
K	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
K	0006986	biological_process	response to unfolded protein
K	0008035	molecular_function	high-density lipoprotein particle binding
K	0008637	biological_process	apoptotic mitochondrial changes
K	0009409	biological_process	response to cold
K	0009986	cellular_component	cell surface
K	0016020	cellular_component	membrane
K	0016853	molecular_function	isomerase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0019899	molecular_function	enzyme binding
K	0030135	cellular_component	coated vesicle
K	0030141	cellular_component	secretory granule
K	0031625	molecular_function	ubiquitin protein ligase binding
K	0032727	biological_process	positive regulation of interferon-alpha production
K	0032729	biological_process	positive regulation of type II interferon production
K	0032733	biological_process	positive regulation of interleukin-10 production
K	0032735	biological_process	positive regulation of interleukin-12 production
K	0032755	biological_process	positive regulation of interleukin-6 production
K	0032991	cellular_component	protein-containing complex
K	0034185	molecular_function	apolipoprotein binding
K	0034186	molecular_function	apolipoprotein A-I binding
K	0034514	biological_process	mitochondrial unfolded protein response
K	0042026	biological_process	protein refolding
K	0042100	biological_process	B cell proliferation
K	0042110	biological_process	T cell activation
K	0042113	biological_process	B cell activation
K	0043032	biological_process	positive regulation of macrophage activation
K	0043065	biological_process	positive regulation of apoptotic process
K	0043066	biological_process	negative regulation of apoptotic process
K	0043231	cellular_component	intracellular membrane-bounded organelle
K	0044406	biological_process	adhesion of symbiont to host
K	0045041	biological_process	protein import into mitochondrial intermembrane space
K	0046696	cellular_component	lipopolysaccharide receptor complex
K	0048291	biological_process	isotype switching to IgG isotypes
K	0050821	biological_process	protein stabilization
K	0050870	biological_process	positive regulation of T cell activation
K	0051082	molecular_function	unfolded protein binding
K	0051087	molecular_function	protein-folding chaperone binding
K	0051131	biological_process	chaperone-mediated protein complex assembly
K	0051604	biological_process	protein maturation
K	0051702	biological_process	biological process involved in interaction with symbiont
K	0070062	cellular_component	extracellular exosome
K	0097225	cellular_component	sperm midpiece
K	0097524	cellular_component	sperm plasma membrane
K	0098761	biological_process	cellular response to interleukin-7
K	0140494	cellular_component	migrasome
K	0140662	molecular_function	ATP-dependent protein folding chaperone
L	0001530	molecular_function	lipopolysaccharide binding
L	0002039	molecular_function	p53 binding
L	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
L	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
L	0003688	molecular_function	DNA replication origin binding
L	0003697	molecular_function	single-stranded DNA binding
L	0003723	molecular_function	RNA binding
L	0003725	molecular_function	double-stranded RNA binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005615	cellular_component	extracellular space
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005759	cellular_component	mitochondrial matrix
L	0005769	cellular_component	early endosome
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0005905	cellular_component	clathrin-coated pit
L	0006457	biological_process	protein folding
L	0006458	biological_process	'de novo' protein folding
L	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
L	0006986	biological_process	response to unfolded protein
L	0008035	molecular_function	high-density lipoprotein particle binding
L	0008637	biological_process	apoptotic mitochondrial changes
L	0009409	biological_process	response to cold
L	0009986	cellular_component	cell surface
L	0016020	cellular_component	membrane
L	0016853	molecular_function	isomerase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0019899	molecular_function	enzyme binding
L	0030135	cellular_component	coated vesicle
L	0030141	cellular_component	secretory granule
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0032727	biological_process	positive regulation of interferon-alpha production
L	0032729	biological_process	positive regulation of type II interferon production
L	0032733	biological_process	positive regulation of interleukin-10 production
L	0032735	biological_process	positive regulation of interleukin-12 production
L	0032755	biological_process	positive regulation of interleukin-6 production
L	0032991	cellular_component	protein-containing complex
L	0034185	molecular_function	apolipoprotein binding
L	0034186	molecular_function	apolipoprotein A-I binding
L	0034514	biological_process	mitochondrial unfolded protein response
L	0042026	biological_process	protein refolding
L	0042100	biological_process	B cell proliferation
L	0042110	biological_process	T cell activation
L	0042113	biological_process	B cell activation
L	0043032	biological_process	positive regulation of macrophage activation
L	0043065	biological_process	positive regulation of apoptotic process
L	0043066	biological_process	negative regulation of apoptotic process
L	0043231	cellular_component	intracellular membrane-bounded organelle
L	0044406	biological_process	adhesion of symbiont to host
L	0045041	biological_process	protein import into mitochondrial intermembrane space
L	0046696	cellular_component	lipopolysaccharide receptor complex
L	0048291	biological_process	isotype switching to IgG isotypes
L	0050821	biological_process	protein stabilization
L	0050870	biological_process	positive regulation of T cell activation
L	0051082	molecular_function	unfolded protein binding
L	0051087	molecular_function	protein-folding chaperone binding
L	0051131	biological_process	chaperone-mediated protein complex assembly
L	0051604	biological_process	protein maturation
L	0051702	biological_process	biological process involved in interaction with symbiont
L	0070062	cellular_component	extracellular exosome
L	0097225	cellular_component	sperm midpiece
L	0097524	cellular_component	sperm plasma membrane
L	0098761	biological_process	cellular response to interleukin-7
L	0140494	cellular_component	migrasome
L	0140662	molecular_function	ATP-dependent protein folding chaperone
M	0001530	molecular_function	lipopolysaccharide binding
M	0002039	molecular_function	p53 binding
M	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
M	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
M	0003688	molecular_function	DNA replication origin binding
M	0003697	molecular_function	single-stranded DNA binding
M	0003723	molecular_function	RNA binding
M	0003725	molecular_function	double-stranded RNA binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005615	cellular_component	extracellular space
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005759	cellular_component	mitochondrial matrix
M	0005769	cellular_component	early endosome
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0005905	cellular_component	clathrin-coated pit
M	0006457	biological_process	protein folding
M	0006458	biological_process	'de novo' protein folding
M	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
M	0006986	biological_process	response to unfolded protein
M	0008035	molecular_function	high-density lipoprotein particle binding
M	0008637	biological_process	apoptotic mitochondrial changes
M	0009409	biological_process	response to cold
M	0009986	cellular_component	cell surface
M	0016020	cellular_component	membrane
M	0016853	molecular_function	isomerase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0019899	molecular_function	enzyme binding
M	0030135	cellular_component	coated vesicle
M	0030141	cellular_component	secretory granule
M	0031625	molecular_function	ubiquitin protein ligase binding
M	0032727	biological_process	positive regulation of interferon-alpha production
M	0032729	biological_process	positive regulation of type II interferon production
M	0032733	biological_process	positive regulation of interleukin-10 production
M	0032735	biological_process	positive regulation of interleukin-12 production
M	0032755	biological_process	positive regulation of interleukin-6 production
M	0032991	cellular_component	protein-containing complex
M	0034185	molecular_function	apolipoprotein binding
M	0034186	molecular_function	apolipoprotein A-I binding
M	0034514	biological_process	mitochondrial unfolded protein response
M	0042026	biological_process	protein refolding
M	0042100	biological_process	B cell proliferation
M	0042110	biological_process	T cell activation
M	0042113	biological_process	B cell activation
M	0043032	biological_process	positive regulation of macrophage activation
M	0043065	biological_process	positive regulation of apoptotic process
M	0043066	biological_process	negative regulation of apoptotic process
M	0043231	cellular_component	intracellular membrane-bounded organelle
M	0044406	biological_process	adhesion of symbiont to host
M	0045041	biological_process	protein import into mitochondrial intermembrane space
M	0046696	cellular_component	lipopolysaccharide receptor complex
M	0048291	biological_process	isotype switching to IgG isotypes
M	0050821	biological_process	protein stabilization
M	0050870	biological_process	positive regulation of T cell activation
M	0051082	molecular_function	unfolded protein binding
M	0051087	molecular_function	protein-folding chaperone binding
M	0051131	biological_process	chaperone-mediated protein complex assembly
M	0051604	biological_process	protein maturation
M	0051702	biological_process	biological process involved in interaction with symbiont
M	0070062	cellular_component	extracellular exosome
M	0097225	cellular_component	sperm midpiece
M	0097524	cellular_component	sperm plasma membrane
M	0098761	biological_process	cellular response to interleukin-7
M	0140494	cellular_component	migrasome
M	0140662	molecular_function	ATP-dependent protein folding chaperone
N	0001530	molecular_function	lipopolysaccharide binding
N	0002039	molecular_function	p53 binding
N	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
N	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
N	0003688	molecular_function	DNA replication origin binding
N	0003697	molecular_function	single-stranded DNA binding
N	0003723	molecular_function	RNA binding
N	0003725	molecular_function	double-stranded RNA binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005615	cellular_component	extracellular space
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005759	cellular_component	mitochondrial matrix
N	0005769	cellular_component	early endosome
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0005905	cellular_component	clathrin-coated pit
N	0006457	biological_process	protein folding
N	0006458	biological_process	'de novo' protein folding
N	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
N	0006986	biological_process	response to unfolded protein
N	0008035	molecular_function	high-density lipoprotein particle binding
N	0008637	biological_process	apoptotic mitochondrial changes
N	0009409	biological_process	response to cold
N	0009986	cellular_component	cell surface
N	0016020	cellular_component	membrane
N	0016853	molecular_function	isomerase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0019899	molecular_function	enzyme binding
N	0030135	cellular_component	coated vesicle
N	0030141	cellular_component	secretory granule
N	0031625	molecular_function	ubiquitin protein ligase binding
N	0032727	biological_process	positive regulation of interferon-alpha production
N	0032729	biological_process	positive regulation of type II interferon production
N	0032733	biological_process	positive regulation of interleukin-10 production
N	0032735	biological_process	positive regulation of interleukin-12 production
N	0032755	biological_process	positive regulation of interleukin-6 production
N	0032991	cellular_component	protein-containing complex
N	0034185	molecular_function	apolipoprotein binding
N	0034186	molecular_function	apolipoprotein A-I binding
N	0034514	biological_process	mitochondrial unfolded protein response
N	0042026	biological_process	protein refolding
N	0042100	biological_process	B cell proliferation
N	0042110	biological_process	T cell activation
N	0042113	biological_process	B cell activation
N	0043032	biological_process	positive regulation of macrophage activation
N	0043065	biological_process	positive regulation of apoptotic process
N	0043066	biological_process	negative regulation of apoptotic process
N	0043231	cellular_component	intracellular membrane-bounded organelle
N	0044406	biological_process	adhesion of symbiont to host
N	0045041	biological_process	protein import into mitochondrial intermembrane space
N	0046696	cellular_component	lipopolysaccharide receptor complex
N	0048291	biological_process	isotype switching to IgG isotypes
N	0050821	biological_process	protein stabilization
N	0050870	biological_process	positive regulation of T cell activation
N	0051082	molecular_function	unfolded protein binding
N	0051087	molecular_function	protein-folding chaperone binding
N	0051131	biological_process	chaperone-mediated protein complex assembly
N	0051604	biological_process	protein maturation
N	0051702	biological_process	biological process involved in interaction with symbiont
N	0070062	cellular_component	extracellular exosome
N	0097225	cellular_component	sperm midpiece
N	0097524	cellular_component	sperm plasma membrane
N	0098761	biological_process	cellular response to interleukin-7
N	0140494	cellular_component	migrasome
N	0140662	molecular_function	ATP-dependent protein folding chaperone
O	0001649	biological_process	osteoblast differentiation
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005739	cellular_component	mitochondrion
O	0005759	cellular_component	mitochondrial matrix
O	0006457	biological_process	protein folding
O	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
O	0006986	biological_process	response to unfolded protein
O	0016020	cellular_component	membrane
O	0044183	molecular_function	protein folding chaperone
O	0046872	molecular_function	metal ion binding
O	0051082	molecular_function	unfolded protein binding
O	0051085	biological_process	chaperone cofactor-dependent protein refolding
O	0051087	molecular_function	protein-folding chaperone binding
O	0070062	cellular_component	extracellular exosome
P	0001649	biological_process	osteoblast differentiation
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005739	cellular_component	mitochondrion
P	0005759	cellular_component	mitochondrial matrix
P	0006457	biological_process	protein folding
P	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
P	0006986	biological_process	response to unfolded protein
P	0016020	cellular_component	membrane
P	0044183	molecular_function	protein folding chaperone
P	0046872	molecular_function	metal ion binding
P	0051082	molecular_function	unfolded protein binding
P	0051085	biological_process	chaperone cofactor-dependent protein refolding
P	0051087	molecular_function	protein-folding chaperone binding
P	0070062	cellular_component	extracellular exosome
Q	0001649	biological_process	osteoblast differentiation
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005739	cellular_component	mitochondrion
Q	0005759	cellular_component	mitochondrial matrix
Q	0006457	biological_process	protein folding
Q	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
Q	0006986	biological_process	response to unfolded protein
Q	0016020	cellular_component	membrane
Q	0044183	molecular_function	protein folding chaperone
Q	0046872	molecular_function	metal ion binding
Q	0051082	molecular_function	unfolded protein binding
Q	0051085	biological_process	chaperone cofactor-dependent protein refolding
Q	0051087	molecular_function	protein-folding chaperone binding
Q	0070062	cellular_component	extracellular exosome
R	0001649	biological_process	osteoblast differentiation
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005524	molecular_function	ATP binding
R	0005739	cellular_component	mitochondrion
R	0005759	cellular_component	mitochondrial matrix
R	0006457	biological_process	protein folding
R	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
R	0006986	biological_process	response to unfolded protein
R	0016020	cellular_component	membrane
R	0044183	molecular_function	protein folding chaperone
R	0046872	molecular_function	metal ion binding
R	0051082	molecular_function	unfolded protein binding
R	0051085	biological_process	chaperone cofactor-dependent protein refolding
R	0051087	molecular_function	protein-folding chaperone binding
R	0070062	cellular_component	extracellular exosome
S	0001649	biological_process	osteoblast differentiation
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005739	cellular_component	mitochondrion
S	0005759	cellular_component	mitochondrial matrix
S	0006457	biological_process	protein folding
S	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
S	0006986	biological_process	response to unfolded protein
S	0016020	cellular_component	membrane
S	0044183	molecular_function	protein folding chaperone
S	0046872	molecular_function	metal ion binding
S	0051082	molecular_function	unfolded protein binding
S	0051085	biological_process	chaperone cofactor-dependent protein refolding
S	0051087	molecular_function	protein-folding chaperone binding
S	0070062	cellular_component	extracellular exosome
T	0001649	biological_process	osteoblast differentiation
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0005524	molecular_function	ATP binding
T	0005739	cellular_component	mitochondrion
T	0005759	cellular_component	mitochondrial matrix
T	0006457	biological_process	protein folding
T	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
T	0006986	biological_process	response to unfolded protein
T	0016020	cellular_component	membrane
T	0044183	molecular_function	protein folding chaperone
T	0046872	molecular_function	metal ion binding
T	0051082	molecular_function	unfolded protein binding
T	0051085	biological_process	chaperone cofactor-dependent protein refolding
T	0051087	molecular_function	protein-folding chaperone binding
T	0070062	cellular_component	extracellular exosome
U	0001649	biological_process	osteoblast differentiation
U	0003723	molecular_function	RNA binding
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005739	cellular_component	mitochondrion
U	0005759	cellular_component	mitochondrial matrix
U	0006457	biological_process	protein folding
U	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
U	0006986	biological_process	response to unfolded protein
U	0016020	cellular_component	membrane
U	0044183	molecular_function	protein folding chaperone
U	0046872	molecular_function	metal ion binding
U	0051082	molecular_function	unfolded protein binding
U	0051085	biological_process	chaperone cofactor-dependent protein refolding
U	0051087	molecular_function	protein-folding chaperone binding
U	0070062	cellular_component	extracellular exosome
V	0001649	biological_process	osteoblast differentiation
V	0003723	molecular_function	RNA binding
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005739	cellular_component	mitochondrion
V	0005759	cellular_component	mitochondrial matrix
V	0006457	biological_process	protein folding
V	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
V	0006986	biological_process	response to unfolded protein
V	0016020	cellular_component	membrane
V	0044183	molecular_function	protein folding chaperone
V	0046872	molecular_function	metal ion binding
V	0051082	molecular_function	unfolded protein binding
V	0051085	biological_process	chaperone cofactor-dependent protein refolding
V	0051087	molecular_function	protein-folding chaperone binding
V	0070062	cellular_component	extracellular exosome
W	0001649	biological_process	osteoblast differentiation
W	0003723	molecular_function	RNA binding
W	0005515	molecular_function	protein binding
W	0005524	molecular_function	ATP binding
W	0005739	cellular_component	mitochondrion
W	0005759	cellular_component	mitochondrial matrix
W	0006457	biological_process	protein folding
W	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
W	0006986	biological_process	response to unfolded protein
W	0016020	cellular_component	membrane
W	0044183	molecular_function	protein folding chaperone
W	0046872	molecular_function	metal ion binding
W	0051082	molecular_function	unfolded protein binding
W	0051085	biological_process	chaperone cofactor-dependent protein refolding
W	0051087	molecular_function	protein-folding chaperone binding
W	0070062	cellular_component	extracellular exosome
X	0001649	biological_process	osteoblast differentiation
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005739	cellular_component	mitochondrion
X	0005759	cellular_component	mitochondrial matrix
X	0006457	biological_process	protein folding
X	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
X	0006986	biological_process	response to unfolded protein
X	0016020	cellular_component	membrane
X	0044183	molecular_function	protein folding chaperone
X	0046872	molecular_function	metal ion binding
X	0051082	molecular_function	unfolded protein binding
X	0051085	biological_process	chaperone cofactor-dependent protein refolding
X	0051087	molecular_function	protein-folding chaperone binding
X	0070062	cellular_component	extracellular exosome
Y	0001649	biological_process	osteoblast differentiation
Y	0003723	molecular_function	RNA binding
Y	0005515	molecular_function	protein binding
Y	0005524	molecular_function	ATP binding
Y	0005739	cellular_component	mitochondrion
Y	0005759	cellular_component	mitochondrial matrix
Y	0006457	biological_process	protein folding
Y	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
Y	0006986	biological_process	response to unfolded protein
Y	0016020	cellular_component	membrane
Y	0044183	molecular_function	protein folding chaperone
Y	0046872	molecular_function	metal ion binding
Y	0051082	molecular_function	unfolded protein binding
Y	0051085	biological_process	chaperone cofactor-dependent protein refolding
Y	0051087	molecular_function	protein-folding chaperone binding
Y	0070062	cellular_component	extracellular exosome
Z	0001649	biological_process	osteoblast differentiation
Z	0003723	molecular_function	RNA binding
Z	0005515	molecular_function	protein binding
Z	0005524	molecular_function	ATP binding
Z	0005739	cellular_component	mitochondrion
Z	0005759	cellular_component	mitochondrial matrix
Z	0006457	biological_process	protein folding
Z	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
Z	0006986	biological_process	response to unfolded protein
Z	0016020	cellular_component	membrane
Z	0044183	molecular_function	protein folding chaperone
Z	0046872	molecular_function	metal ion binding
Z	0051082	molecular_function	unfolded protein binding
Z	0051085	biological_process	chaperone cofactor-dependent protein refolding
Z	0051087	molecular_function	protein-folding chaperone binding
Z	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue ADP J 601

Chain	Residue
J	THR30
J	GLY415
J	GLY416
J	ILE455
J	TYR479
J	ASP480
J	ALA481
J	ASP496
J	BEF602
J	MG603
J	K604
J	MET31
J	PRO33
J	LYS51
J	ASP87
J	GLY88
J	THR90
J	THR91
J	ILE150

---

site_id	AC2
Number of Residues	9
Details	binding site for residue BEF J 602

Chain	Residue
J	GLY53
J	ASP87
J	GLY88
J	THR89
J	THR90
J	THR91
J	ADP601
J	MG603
J	K604

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG J 603

Chain	Residue
J	ASP52
J	ASP87
J	ASP399
J	ADP601
J	BEF602
J	K604

---

site_id	AC4
Number of Residues	5
Details	binding site for residue K J 604

Chain	Residue
J	LYS51
J	ASP52
J	ADP601
J	BEF602
J	MG603

---

site_id	AC5
Number of Residues	17
Details	binding site for residue ADP I 601

Chain	Residue
I	THR30
I	PRO33
I	LYS51
I	ASP87
I	THR90
I	THR91
I	ILE150
I	GLY415
I	GLY416
I	ILE455
I	TYR479
I	ASP480
I	ALA481
I	ASP496
I	BEF602
I	MG603
I	K604

---

site_id	AC6
Number of Residues	9
Details	binding site for residue BEF I 602

Chain	Residue
I	ASP52
I	GLY53
I	ASP87
I	GLY88
I	THR89
I	THR90
I	ADP601
I	MG603
I	K604

---

site_id	AC7
Number of Residues	5
Details	binding site for residue MG I 603

Chain	Residue
I	ASP52
I	ASP87
I	ASP399
I	ADP601
I	BEF602

---

site_id	AC8
Number of Residues	5
Details	binding site for residue K I 604

Chain	Residue
I	THR30
I	LYS51
I	THR90
I	ADP601
I	BEF602

---

site_id	AC9
Number of Residues	18
Details	binding site for residue ADP H 601

Chain	Residue
H	THR30
H	MET31
H	GLY32
H	PRO33
H	LYS51
H	ASP87
H	THR90
H	ILE150
H	GLY416
H	ILE455
H	TYR479
H	ASP480
H	ALA481
H	ILE494
H	ASP496
H	BEF602
H	MG603
H	K604

---

site_id	AD1
Number of Residues	9
Details	binding site for residue BEF H 602

Chain	Residue
H	ADP601
H	MG603
H	K604
H	GLY53
H	ASP87
H	GLY88
H	THR89
H	THR90
H	THR91

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MG H 603

Chain	Residue
H	ASP52
H	ASP87
H	ASP399
H	ADP601
H	BEF602

---

site_id	AD3
Number of Residues	5
Details	binding site for residue K H 604

Chain	Residue
H	THR30
H	LYS51
H	THR90
H	ADP601
H	BEF602

---

site_id	AD4
Number of Residues	18
Details	binding site for residue ADP N 601

Chain	Residue
N	THR30
N	MET31
N	PRO33
N	LYS51
N	ASP87
N	THR90
N	ILE150
N	GLY415
N	GLY416
N	ILE455
N	TYR479
N	ASP480
N	ALA481
N	ILE494
N	ASP496
N	BEF602
N	MG603
N	K604

---

site_id	AD5
Number of Residues	10
Details	binding site for residue BEF N 602

Chain	Residue
N	ASP52
N	GLY53
N	ASP87
N	GLY88
N	THR89
N	THR90
N	THR91
N	ADP601
N	MG603
N	K604

---

site_id	AD6
Number of Residues	5
Details	binding site for residue MG N 603

Chain	Residue
N	ASP87
N	ASP399
N	ADP601
N	BEF602
N	K604

---

site_id	AD7
Number of Residues	5
Details	binding site for residue K N 604

Chain	Residue
N	THR30
N	LYS51
N	ADP601
N	BEF602
N	MG603

---

site_id	AD8
Number of Residues	20
Details	binding site for residue ADP M 601

Chain	Residue
M	THR30
M	GLY32
M	PRO33
M	LYS51
M	ASP87
M	GLY88
M	THR90
M	THR91
M	ILE150
M	GLY415
M	GLY416
M	ILE455
M	TYR479
M	ASP480
M	ALA481
M	ILE494
M	ASP496
M	BEF602
M	MG603
M	K604

---

site_id	AD9
Number of Residues	10
Details	binding site for residue BEF M 602

Chain	Residue
M	LYS51
M	ASP52
M	GLY53
M	ASP87
M	GLY88
M	THR89
M	THR90
M	ADP601
M	MG603
M	K604

---

site_id	AE1
Number of Residues	5
Details	binding site for residue MG M 603

Chain	Residue
M	ASP52
M	ASP87
M	ASP399
M	ADP601
M	BEF602

---

site_id	AE2
Number of Residues	4
Details	binding site for residue K M 604

Chain	Residue
M	THR30
M	LYS51
M	ADP601
M	BEF602

---

site_id	AE3
Number of Residues	14
Details	binding site for residue ADP L 601

Chain	Residue
L	THR30
L	MET31
L	PRO33
L	LYS51
L	ASP87
L	GLY88
L	THR90
L	THR91
L	GLY416
L	ALA481
L	ASP496
L	BEF602
L	MG603
L	K604

---

site_id	AE4
Number of Residues	10
Details	binding site for residue BEF L 602

Chain	Residue
L	ASP52
L	GLY53
L	ASP87
L	GLY88
L	THR89
L	THR90
L	THR91
L	ADP601
L	MG603
L	K604

---

site_id	AE5
Number of Residues	5
Details	binding site for residue MG L 603

Chain	Residue
L	ASP52
L	ASP87
L	ASP399
L	ADP601
L	BEF602

---

site_id	AE6
Number of Residues	5
Details	binding site for residue K L 604

Chain	Residue
L	THR30
L	LYS51
L	THR90
L	ADP601
L	BEF602

---

site_id	AE7
Number of Residues	19
Details	binding site for residue ADP K 601

Chain	Residue
K	THR30
K	MET31
K	GLY32
K	PRO33
K	LYS51
K	ASP87
K	GLY88
K	THR90
K	GLY415
K	GLY416
K	ILE455
K	TYR479
K	ASP480
K	ALA481
K	ILE494
K	ASP496
K	BEF602
K	MG603
K	K604

---

site_id	AE8
Number of Residues	9
Details	binding site for residue BEF K 602

Chain	Residue
K	GLY53
K	ASP87
K	GLY88
K	THR89
K	THR90
K	THR91
K	ADP601
K	MG603
K	K604

---

site_id	AE9
Number of Residues	5
Details	binding site for residue MG K 603

Chain	Residue
K	ASP52
K	ASP87
K	ASP399
K	ADP601
K	BEF602

---

site_id	AF1
Number of Residues	5
Details	binding site for residue K K 604

Chain	Residue
K	THR30
K	LYS51
K	THR90
K	ADP601
K	BEF602

---

site_id	AF2
Number of Residues	19
Details	binding site for residue ADP G 601

Chain	Residue
G	THR30
G	MET31
G	PRO33
G	LYS51
G	ASP87
G	GLY88
G	THR90
G	ILE150
G	GLY415
G	GLY416
G	ILE455
G	TYR479
G	ASP480
G	ALA481
G	ILE494
G	ASP496
G	BEF602
G	MG603
G	K604

---

site_id	AF3
Number of Residues	10
Details	binding site for residue BEF G 602

Chain	Residue
G	ASP52
G	GLY53
G	ASP87
G	GLY88
G	THR89
G	THR90
G	THR91
G	ADP601
G	MG603
G	K604

---

site_id	AF4
Number of Residues	5
Details	binding site for residue MG G 603

Chain	Residue
G	ASP52
G	ASP87
G	ASP399
G	ADP601
G	BEF602

---

site_id	AF5
Number of Residues	7
Details	binding site for residue K G 604

Chain	Residue
G	THR30
G	LYS51
G	ASP52
G	GLY53
G	THR90
G	ADP601
G	BEF602

---

site_id	AF6
Number of Residues	16
Details	binding site for residue ADP F 601

Chain	Residue
F	THR30
F	MET31
F	PRO33
F	ASP87
F	GLY88
F	THR90
F	ILE150
F	GLY416
F	ILE455
F	TYR479
F	ASP480
F	ALA481
F	ASP496
F	BEF602
F	MG603
F	K604

---

site_id	AF7
Number of Residues	8
Details	binding site for residue BEF F 602

Chain	Residue
F	GLY53
F	ASP87
F	GLY88
F	THR89
F	THR90
F	THR91
F	ADP601
F	MG603

---

site_id	AF8
Number of Residues	5
Details	binding site for residue MG F 603

Chain	Residue
F	ASP52
F	ASP87
F	ASP399
F	ADP601
F	BEF602

---

site_id	AF9
Number of Residues	3
Details	binding site for residue K F 604

Chain	Residue
F	THR30
F	LYS51
F	ADP601

---

site_id	AG1
Number of Residues	20
Details	binding site for residue ADP E 601

Chain	Residue
E	THR30
E	MET31
E	GLY32
E	PRO33
E	LYS51
E	ASP87
E	GLY88
E	THR90
E	ILE150
E	GLY415
E	GLY416
E	ILE455
E	TYR479
E	ASP480
E	ALA481
E	ILE494
E	ASP496
E	BEF602
E	MG603
E	K604

---

site_id	AG2
Number of Residues	9
Details	binding site for residue BEF E 602

Chain	Residue
E	ASP52
E	GLY53
E	ASP87
E	GLY88
E	THR89
E	THR90
E	ADP601
E	MG603
E	K604

---

site_id	AG3
Number of Residues	5
Details	binding site for residue MG E 603

Chain	Residue
E	ASP87
E	ASP399
E	ADP601
E	BEF602
E	K604

---

site_id	AG4
Number of Residues	5
Details	binding site for residue K E 604

Chain	Residue
E	THR30
E	LYS51
E	ADP601
E	BEF602
E	MG603

---

site_id	AG5
Number of Residues	20
Details	binding site for residue ADP D 601

Chain	Residue
D	THR30
D	MET31
D	GLY32
D	PRO33
D	LYS51
D	ASP87
D	GLY88
D	THR90
D	THR91
D	GLY415
D	GLY416
D	ILE455
D	TYR479
D	ASP480
D	ALA481
D	ILE494
D	ASP496
D	BEF602
D	MG603
D	K604

---

site_id	AG6
Number of Residues	9
Details	binding site for residue BEF D 602

Chain	Residue
D	ASP52
D	GLY53
D	ASP87
D	GLY88
D	THR89
D	THR90
D	ADP601
D	MG603
D	K604

---

site_id	AG7
Number of Residues	5
Details	binding site for residue MG D 603

Chain	Residue
D	ASP52
D	ASP87
D	ASP399
D	ADP601
D	BEF602

---

site_id	AG8
Number of Residues	5
Details	binding site for residue K D 604

Chain	Residue
D	THR30
D	LYS51
D	THR90
D	ADP601
D	BEF602

---

site_id	AG9
Number of Residues	19
Details	binding site for residue ADP C 601

Chain	Residue
C	THR30
C	MET31
C	GLY32
C	PRO33
C	LYS51
C	ASP87
C	GLY88
C	THR91
C	ILE150
C	GLY416
C	ILE455
C	TYR479
C	ASP480
C	ALA481
C	ILE494
C	ASP496
C	BEF602
C	MG603
C	K604

---

site_id	AH1
Number of Residues	9
Details	binding site for residue BEF C 602

Chain	Residue
C	ASP52
C	GLY53
C	ASP87
C	GLY88
C	THR89
C	THR90
C	ADP601
C	MG603
C	K604

---

site_id	AH2
Number of Residues	5
Details	binding site for residue MG C 603

Chain	Residue
C	ASP52
C	ASP87
C	ASP399
C	ADP601
C	BEF602

---

site_id	AH3
Number of Residues	5
Details	binding site for residue K C 604

Chain	Residue
C	THR30
C	LYS51
C	THR90
C	ADP601
C	BEF602

---

site_id	AH4
Number of Residues	16
Details	binding site for residue ADP B 601

Chain	Residue
B	THR30
B	MET31
B	GLY32
B	PRO33
B	LYS51
B	ASP87
B	THR90
B	ILE150
B	GLY416
B	ASP480
B	ALA481
B	ILE494
B	ASP496
B	BEF602
B	MG603
B	K604

---

site_id	AH5
Number of Residues	9
Details	binding site for residue BEF B 602

Chain	Residue
B	GLY53
B	ASP87
B	GLY88
B	THR89
B	THR90
B	THR91
B	ADP601
B	MG603
B	K604

---

site_id	AH6
Number of Residues	5
Details	binding site for residue MG B 603

Chain	Residue
B	ASP52
B	ASP87
B	ASP399
B	ADP601
B	BEF602

---

site_id	AH7
Number of Residues	5
Details	binding site for residue K B 604

Chain	Residue
B	THR30
B	LYS51
B	THR90
B	ADP601
B	BEF602

---

site_id	AH8
Number of Residues	18
Details	binding site for residue ADP A 601

Chain	Residue
A	THR30
A	PRO33
A	LYS51
A	ASP87
A	THR90
A	THR91
A	ILE150
A	GLY415
A	GLY416
A	ILE455
A	TYR479
A	ASP480
A	ALA481
A	ILE494
A	ASP496
A	BEF602
A	MG603
A	K604

---

site_id	AH9
Number of Residues	10
Details	binding site for residue BEF A 602

Chain	Residue
A	ASP52
A	GLY53
A	ASP87
A	GLY88
A	THR89
A	THR90
A	THR91
A	ADP601
A	MG603
A	K604

---

site_id	AI1
Number of Residues	5
Details	binding site for residue MG A 603

Chain	Residue
A	ASP52
A	ASP87
A	ASP399
A	ADP601
A	BEF602

---

site_id	AI2
Number of Residues	5
Details	binding site for residue K A 604

Chain	Residue
A	THR30
A	LYS51
A	THR90
A	ADP601
A	BEF602

---

Functional Information from PROSITE/UniProt

site_id	PS00681
Number of Residues	25
Details	CHAPERONINS_CPN10 Chaperonins cpn10 signature. FlPLfDRVLVErsaaetvtkGgIML

Chain	Residue	Details
X	PHE9-LEU33

---

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGIVlGGG

Chain	Residue	Details
J	ALA406-GLY417

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	MOD_RES: N-acetylalanine => ECO:0000269|Ref.10

Chain	Residue	Details
N	GLY416
N	ASP496
M	LYS51
M	ASP87
M	GLY416
M	ASP496
L	LYS51
L	ASP87
L	GLY416
L	ASP496
K	LYS51
K	ASP87
K	GLY416
K	ASP496
G	LYS51
G	ASP87
G	GLY416
G	ASP496
F	LYS51
F	ASP87
F	GLY416
F	ASP496
E	LYS51
E	ASP87
E	GLY416
E	ASP496
D	LYS51
D	ASP87
D	GLY416
D	ASP496
C	LYS51
C	ASP87
C	GLY416
C	ASP496
B	LYS51
B	ASP87
B	GLY416
B	ASP496
A	LYS51
A	ASP87
A	GLY416
A	ASP496
X	ALA2
W	ALA2
V	ALA2
2	ALA2
1	ALA2
Z	ALA2
Y	ALA2
U	ALA2
T	ALA2
S	ALA2
R	ALA2
Q	ALA2
P	ALA2
O	ALA2

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q64433

Chain	Residue	Details
V	LYS8
2	LYS8
1	LYS8
Z	LYS8
Y	LYS8
U	LYS8
T	LYS8
S	LYS8
R	LYS8
Q	LYS8
P	LYS8
O	LYS8
G	LYS7
G	LYS277
F	LYS7
F	LYS277
E	LYS7
E	LYS277
D	LYS7
D	LYS277
C	LYS7
C	LYS277
B	LYS7
B	LYS277
A	LYS277
X	LYS8
W	LYS8
A	LYS7

---

site_id	SWS_FT_FI3
Number of Residues	14
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q64433

Chain	Residue	Details
X	LYS28
W	LYS28
V	LYS28
2	LYS28
1	LYS28
Z	LYS28
Y	LYS28
U	LYS28
T	LYS28
S	LYS28
R	LYS28
Q	LYS28
P	LYS28
O	LYS28

---

site_id	SWS_FT_FI4
Number of Residues	98
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q64433

Chain	Residue	Details
X	LYS40
X	LYS54
X	LYS56
X	LYS66
X	LYS70
X	LYS80
X	LYS86
W	LYS40
W	LYS54
W	LYS56
W	LYS66
W	LYS70
W	LYS80
W	LYS86
V	LYS40
V	LYS54
V	LYS56
V	LYS66
V	LYS70
V	LYS80
V	LYS86
2	LYS40
2	LYS54
2	LYS56
2	LYS66
2	LYS70
2	LYS80
2	LYS86
1	LYS40
1	LYS54
1	LYS56
1	LYS66
1	LYS70
1	LYS80
1	LYS86
Z	LYS40
Z	LYS54
Z	LYS56
Z	LYS66
Z	LYS70
Z	LYS80
Z	LYS86
Y	LYS40
Y	LYS54
Y	LYS56
Y	LYS66
Y	LYS70
Y	LYS80
Y	LYS86
U	LYS40
U	LYS54
U	LYS56
U	LYS66
U	LYS70
U	LYS80
U	LYS86
T	LYS40
T	LYS54
T	LYS56
T	LYS66
T	LYS70
T	LYS80
T	LYS86
S	LYS40
S	LYS54
S	LYS56
S	LYS66
S	LYS70
S	LYS80
S	LYS86
R	LYS40
R	LYS54
R	LYS56
R	LYS66
R	LYS70
R	LYS80
R	LYS86
Q	LYS40
Q	LYS54
Q	LYS56
Q	LYS66
Q	LYS70
Q	LYS80
Q	LYS86
P	LYS40
P	LYS54
P	LYS56
P	LYS66
P	LYS70
P	LYS80
P	LYS86
O	LYS40
O	LYS54
O	LYS56
O	LYS66
O	LYS70
O	LYS80
O	LYS86

---

site_id	SWS_FT_FI5
Number of Residues	14
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
I	LYS290
I	LYS365
H	LYS51
H	LYS63
H	LYS67
H	LYS132
H	LYS225
H	LYS268
H	LYS290
H	LYS365
N	LYS51
N	LYS63
N	LYS67
N	LYS132
N	LYS225
N	LYS268
N	LYS290
N	LYS365
M	LYS51
M	LYS63
M	LYS67
M	LYS132
M	LYS225
M	LYS268
M	LYS290
M	LYS365
L	LYS51
L	LYS63
L	LYS67
L	LYS132
L	LYS225
L	LYS268
L	LYS290
L	LYS365
K	LYS51
K	LYS63
K	LYS67
K	LYS132
K	LYS225
K	LYS268
K	LYS290
K	LYS365
G	LYS51
G	LYS63
G	LYS67
G	LYS132
G	LYS225
G	LYS268
G	LYS290
G	LYS365
F	LYS51
F	LYS63
F	LYS67
F	LYS132
F	LYS225
F	LYS268
F	LYS290
F	LYS365
E	LYS51
E	LYS63
E	LYS67
E	LYS132
E	LYS225
E	LYS268
E	LYS290
E	LYS365
D	LYS51
D	LYS63
D	LYS67
D	LYS132
D	LYS225
D	LYS268
D	LYS290
D	LYS365
C	LYS51
C	LYS63
C	LYS67
C	LYS132
C	LYS225
C	LYS268
C	LYS290
C	LYS365
B	LYS51
B	LYS63
B	LYS67
B	LYS132
B	LYS225
B	LYS268
B	LYS290
B	LYS365
A	LYS51
A	LYS63
A	LYS67
A	LYS132
A	LYS225
A	LYS268
A	LYS290
A	LYS365
X	THR79
W	THR79
V	THR79
2	THR79
1	THR79
Z	THR79
Y	THR79
U	THR79
T	THR79
S	THR79
R	THR79
Q	THR79
P	THR79
O	THR79

---

site_id	SWS_FT_FI6
Number of Residues	14
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
W	LYS99
V	LYS99
2	LYS99
1	LYS99
Z	LYS99
Y	LYS99
U	LYS99
T	LYS99
S	LYS99
R	LYS99
Q	LYS99
P	LYS99
O	LYS99
I	LYS109
I	LYS167
I	LYS178
I	LYS181
I	LYS194
I	LYS212
I	LYS226
I	LYS328
I	LYS372
I	LYS457
H	LYS58
H	LYS101
H	LYS109
H	LYS167
H	LYS178
H	LYS181
H	LYS194
H	LYS212
H	LYS226
H	LYS328
H	LYS372
H	LYS457
N	LYS58
N	LYS101
N	LYS109
N	LYS167
N	LYS178
N	LYS181
N	LYS194
N	LYS212
N	LYS226
N	LYS328
N	LYS372
N	LYS457
M	LYS58
M	LYS101
M	LYS109
M	LYS167
M	LYS178
M	LYS181
M	LYS194
M	LYS212
M	LYS226
M	LYS328
M	LYS372
M	LYS457
L	LYS58
L	LYS101
L	LYS109
L	LYS167
L	LYS178
L	LYS181
L	LYS194
L	LYS212
L	LYS226
L	LYS328
L	LYS372
L	LYS457
K	LYS58
K	LYS101
K	LYS109
K	LYS167
K	LYS178
K	LYS181
K	LYS194
K	LYS212
K	LYS226
K	LYS328
K	LYS372
K	LYS457
G	LYS58
G	LYS101
G	LYS109
G	LYS167
G	LYS178
G	LYS181
G	LYS194
G	LYS212
G	LYS226
G	LYS328
G	LYS372
G	LYS457
F	LYS58
F	LYS101
F	LYS109
F	LYS167
F	LYS178
F	LYS181
F	LYS194
F	LYS212
F	LYS226
F	LYS328
F	LYS372
F	LYS457
E	LYS58
E	LYS101
E	LYS109
E	LYS167
E	LYS178
E	LYS181
E	LYS194
E	LYS212
E	LYS226
E	LYS328
E	LYS372
E	LYS457
D	LYS58
D	LYS101
D	LYS109
D	LYS167
D	LYS178
D	LYS181
D	LYS194
D	LYS212
D	LYS226
D	LYS328
D	LYS372
D	LYS457
C	LYS58
C	LYS101
C	LYS109
C	LYS167
C	LYS178
C	LYS181
C	LYS194
C	LYS212
C	LYS226
C	LYS328
C	LYS372
C	LYS457
B	LYS58
B	LYS101
B	LYS109
B	LYS167
B	LYS178
B	LYS181
B	LYS194
B	LYS212
B	LYS226
B	LYS328
B	LYS372
B	LYS457
A	LYS58
A	LYS101
A	LYS109
A	LYS167
A	LYS178
A	LYS181
A	LYS194
A	LYS212
A	LYS226
A	LYS328
A	LYS372
A	LYS457
X	LYS99

---

site_id	SWS_FT_FI7
Number of Residues	14
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
H	TYR66
N	TYR66
M	TYR66
L	TYR66
K	TYR66
G	TYR66
F	TYR66
E	TYR66
D	TYR66
C	TYR66
B	TYR66
A	TYR66
J	TYR66
I	TYR66

---

site_id	SWS_FT_FI8
Number of Residues	56
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
J	LYS245
J	LYS335
J	LYS445
N	LYS106
N	LYS335
N	LYS445
M	LYS106
M	LYS245
M	LYS335
M	LYS445
L	LYS106
L	LYS245
L	LYS335
L	LYS445
K	LYS106
K	LYS245
K	LYS335
K	LYS445
G	LYS106
G	LYS245
G	LYS335
G	LYS445
F	LYS106
F	LYS245
F	LYS335
F	LYS445
E	LYS106
E	LYS245
E	LYS335
E	LYS445
D	LYS106
D	LYS245
D	LYS335
D	LYS445
C	LYS106
C	LYS245
C	LYS335
C	LYS445
B	LYS106
B	LYS245
B	LYS335
B	LYS445
A	LYS106
A	LYS245
A	LYS335
A	LYS445
J	LYS106
I	LYS106
I	LYS245
I	LYS335
I	LYS445
H	LYS106
H	LYS245
H	LYS335
H	LYS445
N	LYS245

---

site_id	SWS_FT_FI9
Number of Residues	14
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
I	SER386
H	SER386
N	SER386
M	SER386
L	SER386
K	SER386
G	SER386
F	SER386
E	SER386
D	SER386
C	SER386
B	SER386
A	SER386
J	SER386

---

site_id	SWS_FT_FI10
Number of Residues	14
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
J	SER464
I	SER464
H	SER464
N	SER464
M	SER464
L	SER464
K	SER464
G	SER464
F	SER464
E	SER464
D	SER464
C	SER464
B	SER464
A	SER464

---

site_id	SWS_FT_FI11
Number of Residues	28
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
G	LYS527
F	LYS527
E	LYS527
D	LYS527
C	LYS527
B	LYS527
A	LYS527
J	LYS527
I	LYS527
H	LYS527
N	LYS527
M	LYS527
L	LYS527
K	LYS527

---