6HSR

The crystal structure of type II Dehydroquinase from Psychromonas ingrahamii 37, 40% ethanol as cryoprotectant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003855	molecular_function	3-dehydroquinate dehydratase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016829	molecular_function	lyase activity
A	0019631	biological_process	quinate catabolic process
B	0003855	molecular_function	3-dehydroquinate dehydratase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0016829	molecular_function	lyase activity
B	0019631	biological_process	quinate catabolic process
C	0003855	molecular_function	3-dehydroquinate dehydratase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0016829	molecular_function	lyase activity
C	0019631	biological_process	quinate catabolic process
D	0003855	molecular_function	3-dehydroquinate dehydratase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0016829	molecular_function	lyase activity
D	0019631	biological_process	quinate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EOH A 201

Chain	Residue
A	ALA79
A	ALA80
A	HIS83
A	ARG114
A	SO4202
B	HOH311

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 202

Chain	Residue
A	SER105
A	EOH201
A	ASN77
A	HIS103
A	LEU104

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 203

Chain	Residue
A	LYS29
A	GLY131
A	ALA132

---

site_id	AC4
Number of Residues	4
Details	binding site for residue EOH B 201

Chain	Residue
B	ALA79
B	HIS83
B	ARG114
B	SO4202

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 B 202

Chain	Residue
B	ASN77
B	HIS103
B	LEU104
B	SER105
B	EOH201
B	HOH309

---

site_id	AC6
Number of Residues	3
Details	binding site for residue SO4 B 203

Chain	Residue
B	LYS29
B	GLY131
B	ALA132

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 B 204

Chain	Residue
B	GLU111
B	SER112
B	HOH308

---

site_id	AC8
Number of Residues	5
Details	binding site for residue EOH C 201

Chain	Residue
C	ALA79
C	ALA80
C	HIS83
C	ARG114
C	SO4202

---

site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 C 202

Chain	Residue
C	ASN77
C	HIS103
C	LEU104
C	SER105
C	EOH201

---

site_id	AD1
Number of Residues	3
Details	binding site for residue SO4 C 203

Chain	Residue
C	LYS29
C	GLY131
C	ALA132

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EOH D 201

Chain	Residue
D	ALA79
D	ALA80
D	HIS83
D	ARG114
D	SO4202

---

site_id	AD3
Number of Residues	7
Details	binding site for residue SO4 D 202

Chain	Residue
D	ASN77
D	ALA79
D	HIS103
D	LEU104
D	SER105
D	EOH201
D	HOH346

---

site_id	AD4
Number of Residues	4
Details	binding site for residue SO4 D 203

Chain	Residue
D	LYS29
D	GLY131
D	ALA132
D	HOH340

---

site_id	AD5
Number of Residues	3
Details	binding site for residue SO4 D 204

Chain	Residue
D	ARG56
D	HOH304
D	HOH321

---

Functional Information from PROSITE/UniProt

site_id	PS01029
Number of Residues	18
Details	DEHYDROQUINASE_II Dehydroquinase class II signature. LNGPNLnlLGqREpevYG

Chain	Residue	Details
A	LEU10-GLY27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00169

Chain	Residue	Details
A	TYR26
B	TYR26
C	TYR26
D	TYR26

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00169

Chain	Residue	Details
A	HIS103
B	HIS103
C	HIS103
D	HIS103

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00169

Chain	Residue	Details
D	HIS83
D	ASP90
D	LEU104
D	ARG114
B	HIS83
A	ASN77
A	HIS83
A	ASP90
A	LEU104
A	ARG114
B	ASN77
B	ASP90
B	LEU104
B	ARG114
C	ASN77
C	HIS83
C	ASP90
C	LEU104
C	ARG114
D	ASN77

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00169

Chain	Residue	Details
A	ARG21
B	ARG21
C	ARG21
D	ARG21

---