Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6HSO

Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006777	biological_process	Mo-molybdopterin cofactor biosynthetic process
A	0032324	biological_process	molybdopterin cofactor biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue MPD A 801

Chain	Residue
A	ARG704
A	ASN707
A	LEU736
A	HOH901
A	HOH934
A	HOH973
A	HOH995
A	HOH1144
A	HOH1152

site_id	AC2
Number of Residues	4
Details	binding site for residue ACT A 802

Chain	Residue
A	ARG675
A	HOH957
A	HOH977
A	HOH1208

site_id	AC3
Number of Residues	1
Details	binding site for residue MPD A 803

Chain	Residue
A	LEU736

site_id	AC4
Number of Residues	2
Details	binding site for residue ACT A 804

Chain	Residue
A	GLY734
A	LEU736

site_id	AC5
Number of Residues	1
Details	binding site for residue ACT A 805

Chain	Residue
A	CYS469

site_id	AC6
Number of Residues	3
Details	binding site for residue ACT A 806

Chain	Residue
A	SER705
A	HOH995
A	HOH1152

site_id	AC7
Number of Residues	3
Details	binding site for residue ACT A 807

Chain	Residue
A	LEU700
A	MET701
A	SER702

site_id	AC8
Number of Residues	6
Details	binding site for residue ACT A 808

Chain	Residue
A	ASN512
A	ASN512
A	GLU514
A	GLU514
A	HOH903
A	HOH903

site_id	AC9
Number of Residues	6
Details	binding site for residue MG A 809

Chain	Residue
A	ADP811
A	HOH922
A	HOH928
A	HOH998
A	HOH1050
A	HOH1147

site_id	AD1
Number of Residues	4
Details	binding site for residue MG A 810

Chain	Residue
A	SER575
A	ASP580
A	ADP811
A	HOH1153

site_id	AD2
Number of Residues	25
Details	binding site for residue ADP A 811

Chain	Residue
A	SER505
A	GLU509
A	LEU510
A	ILE522
A	ASP524
A	SER525
A	ASN526
A	GLY572
A	GLY573
A	VAL574
A	SER575
A	ASP580
A	PRO625
A	GLY626
A	ASN627
A	PRO628
A	MG809
A	MG810
A	HOH928
A	HOH998
A	HOH1050
A	HOH1055
A	HOH1077
A	HOH1109
A	HOH1147

site_id	AD3
Number of Residues	3
Details	binding site for residue PO4 A 812

Chain	Residue
A	VAL500
A	ASP566
A	LYS619

site_id	AD4
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AD5
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AD6
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AD7
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502
A	ASP327
D	PHE398

site_id	AD8
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AD9
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AE1
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AE2
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AE3
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AE4
Number of Residues	10
Details	binding site for Ligand SER I 399 bound to SER D 399

Chain	Residue
A	ASP327
D	PHE398
D	SER399
D	ILE400
D	VAL401
D	HOH1302
I	PHE398
I	ILE400
I	VAL401
I	HOH502

site_id	AE5
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AE6
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AE7
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AE8
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AE9
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AF1
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AF2
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AF3
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AF4
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AF5
Number of Residues	11
Details	binding site for Ligand SER I 403 bound to SER D 403

Chain	Residue
A	LYS658
A	PRO713
A	ASP729
A	HOH1033
D	VAL401
D	GLY402
D	SER403
D	LEU404
I	VAL401
I	GLY402
I	LEU404

site_id	AF6
Number of Residues	20
Details	binding site for Di-peptide 3F7 D 1201 and CYS I 408

Chain	Residue
A	ARG660
A	ARG660
A	TYR719
A	TYR719
A	HIS723
A	HIS723
A	LYS724
A	LYS724
A	GLU726
A	GLU726
D	PRO405
D	ARG406
D	ASP407
D	ASP407
D	HOH1304
D	HOH1304
D	HOH1305
D	HOH1305
I	ASP407
I	ASP407

site_id	AF7
Number of Residues	20
Details	binding site for Di-peptide 3F7 D 1201 and CYS I 408

Chain	Residue
A	ARG660
A	ARG660
A	TYR719
A	TYR719
A	HIS723
A	HIS723
A	LYS724
A	LYS724
A	GLU726
A	GLU726
D	PRO405
D	ARG406
D	ASP407
D	ASP407
D	HOH1304
D	HOH1304
D	HOH1305
D	HOH1305
I	ASP407
I	ASP407

Functional Information from PROSITE/UniProt

site_id	PS01079
Number of Residues	36
Details	MOCF_BIOSYNTHESIS_2 Molybdenum cofactor biosynthesis proteins signature 2. SmGekDylkqvLdidlhaqihfgrVfmKPGLPttFA

Chain	Residue	Details
A	SER575-ALA610

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)