6HSM
Structure of partially reduced RsrR in space group P2(1)2(1)2(1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0051536 | molecular_function | iron-sulfur cluster binding |
| E | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0051536 | molecular_function | iron-sulfur cluster binding |
| F | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0005829 | cellular_component | cytosol |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0051536 | molecular_function | iron-sulfur cluster binding |
| G | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| H | 0003700 | molecular_function | DNA-binding transcription factor activity |
| H | 0005829 | cellular_component | cytosol |
| H | 0006355 | biological_process | regulation of DNA-templated transcription |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0051536 | molecular_function | iron-sulfur cluster binding |
| H | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue FES A 201 |
| Chain | Residue |
| A | GLU8 |
| A | HIS12 |
| D | CYS90 |
| D | ILE93 |
| D | ARG94 |
| D | CYS110 |
| D | ALA113 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MPD A 202 |
| Chain | Residue |
| A | GLU157 |
| A | MPD205 |
| A | HOH309 |
| A | HOH347 |
| A | GLY150 |
| A | ALA153 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MPD A 203 |
| Chain | Residue |
| A | HIS12 |
| A | VAL139 |
| D | THR101 |
| D | CYS110 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MPD A 204 |
| Chain | Residue |
| A | ARG94 |
| D | HIS12 |
| D | VAL139 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue MPD A 205 |
| Chain | Residue |
| A | MPD202 |
| B | ALA125 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MPD A 206 |
| Chain | Residue |
| A | VAL35 |
| E | TRP154 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue MPD A 207 |
| Chain | Residue |
| A | SER21 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 208 |
| Chain | Residue |
| A | ASP85 |
| A | GLU120 |
| A | TRP123 |
| A | ARG124 |
| A | HOH328 |
| D | MET1 |
| D | HOH332 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue FES A 209 |
| Chain | Residue |
| A | CYS90 |
| A | ILE93 |
| A | ARG94 |
| A | CYS110 |
| A | ALA113 |
| D | GLU8 |
| D | HIS12 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue MPD D 201 |
| Chain | Residue |
| A | PRO98 |
| D | TRP154 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue MPD D 202 |
| Chain | Residue |
| D | ALA113 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue MPD D 203 |
| Chain | Residue |
| D | SER48 |
| D | GLY51 |
| D | VAL53 |
| D | SER55 |
| D | THR66 |
| H | LEU65 |
| H | ARG67 |
| H | PRO68 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue MPD D 204 |
| Chain | Residue |
| B | THR18 |
| B | ALA20 |
| B | SER21 |
| D | ALA122 |
| D | ALA125 |
| D | SER126 |
| D | HOH379 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue MPD D 205 |
| Chain | Residue |
| A | ALA115 |
| D | LEU135 |
| D | THR138 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue MPD D 206 |
| Chain | Residue |
| A | ILE93 |
| D | VAL35 |
| D | TYR39 |
| D | GOL207 |
| D | HOH366 |
| D | HOH367 |
| D | HOH374 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL D 207 |
| Chain | Residue |
| D | SER4 |
| D | GLY5 |
| D | TYR39 |
| D | MPD206 |
| D | HOH325 |
| D | HOH381 |
| E | SER4 |
| E | GLY5 |
| E | HOH318 |
| E | HOH374 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 208 |
| Chain | Residue |
| D | LYS108 |
| D | ALA109 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue FES B 201 |
| Chain | Residue |
| B | GLU8 |
| B | HIS12 |
| C | CYS90 |
| C | ILE93 |
| C | ARG94 |
| C | CYS110 |
| C | ALA113 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MPD B 202 |
| Chain | Residue |
| B | HIS12 |
| B | VAL139 |
| B | HOH340 |
| C | ARG94 |
| C | THR101 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue MPD B 203 |
| Chain | Residue |
| B | GLY150 |
| B | GLU157 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MPD B 204 |
| Chain | Residue |
| B | ARG94 |
| B | CYS110 |
| B | HOH313 |
| B | HOH333 |
| C | HIS12 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue MPD B 205 |
| Chain | Residue |
| A | ALA128 |
| B | ASP146 |
| A | ARG124 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue MPD B 206 |
| Chain | Residue |
| B | MET1 |
| B | ALA87 |
| B | GLU120 |
| B | TRP123 |
| B | HOH360 |
| C | ALA87 |
| C | GLU120 |
| C | TRP123 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue MPD B 207 |
| Chain | Residue |
| B | ASP34 |
| B | VAL35 |
| B | HOH336 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 208 |
| Chain | Residue |
| B | PRO68 |
| B | ALA69 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 209 |
| Chain | Residue |
| B | LEU159 |
| B | HIS163 |
| B | HOH335 |
| C | ASP134 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue FES B 210 |
| Chain | Residue |
| B | CYS90 |
| B | ILE93 |
| B | ARG94 |
| B | CYS110 |
| B | ALA113 |
| C | GLU8 |
| C | HIS12 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue MPD C 201 |
| Chain | Residue |
| C | SER4 |
| C | GLY5 |
| C | GLY6 |
| C | TYR39 |
| C | GLN43 |
| F | SER4 |
| F | GLY5 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue MPD C 202 |
| Chain | Residue |
| C | ARG49 |
| E | ARG54 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 203 |
| Chain | Residue |
| B | GLU142 |
| B | SER143 |
| C | ARG94 |
| C | LYS105 |
| C | CYS106 |
| C | THR107 |
| C | LYS108 |
| site_id | AF4 |
| Number of Residues | 8 |
| Details | binding site for residue FES E 201 |
| Chain | Residue |
| E | CYS90 |
| E | GLU92 |
| E | ILE93 |
| E | ARG94 |
| E | CYS110 |
| E | ALA113 |
| G | GLU8 |
| G | HIS12 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue FES E 202 |
| Chain | Residue |
| E | GLU8 |
| E | HIS12 |
| G | CYS90 |
| G | ILE93 |
| G | ARG94 |
| G | CYS110 |
| G | ALA113 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue MPD E 203 |
| Chain | Residue |
| E | HIS12 |
| E | SER143 |
| E | HOH302 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 204 |
| Chain | Residue |
| E | ALA26 |
| E | SER55 |
| E | GLY62 |
| E | TYR63 |
| E | HOH338 |
| site_id | AF8 |
| Number of Residues | 10 |
| Details | binding site for residue MES E 205 |
| Chain | Residue |
| A | MET1 |
| A | LYS2 |
| D | ASP82 |
| E | VAL35 |
| E | SER36 |
| E | TYR39 |
| E | HOH322 |
| E | HOH329 |
| E | HOH339 |
| G | ILE93 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue MPD G 201 |
| Chain | Residue |
| E | THR138 |
| G | PRO111 |
| G | HOH305 |
| G | HOH315 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue MPD G 202 |
| Chain | Residue |
| G | GLN57 |
| G | ALA109 |
| G | ALA113 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue MPD G 203 |
| Chain | Residue |
| G | ARG54 |
| G | THR66 |
| G | GLN95 |
| site_id | AG3 |
| Number of Residues | 8 |
| Details | binding site for residue FES F 201 |
| Chain | Residue |
| F | GLU8 |
| F | HIS12 |
| H | CYS90 |
| H | GLU92 |
| H | ILE93 |
| H | ARG94 |
| H | CYS110 |
| H | ALA113 |
| site_id | AG4 |
| Number of Residues | 2 |
| Details | binding site for residue MPD F 202 |
| Chain | Residue |
| F | HIS12 |
| F | VAL139 |
| site_id | AG5 |
| Number of Residues | 7 |
| Details | binding site for residue MPD F 203 |
| Chain | Residue |
| C | TRP9 |
| C | TYR39 |
| F | MET1 |
| F | LYS2 |
| F | HOH303 |
| F | HOH330 |
| H | LYS2 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL F 204 |
| Chain | Residue |
| F | TRP154 |
| H | PRO98 |
| site_id | AG7 |
| Number of Residues | 1 |
| Details | binding site for residue CL F 205 |
| Chain | Residue |
| F | ALA69 |
| site_id | AG8 |
| Number of Residues | 8 |
| Details | binding site for residue FES F 206 |
| Chain | Residue |
| F | CYS90 |
| F | GLU92 |
| F | ILE93 |
| F | ARG94 |
| F | CYS110 |
| F | ALA113 |
| H | GLU8 |
| H | HIS12 |
| site_id | AG9 |
| Number of Residues | 1 |
| Details | binding site for residue MPD H 201 |
| Chain | Residue |
| H | HIS12 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue MPD H 202 |
| Chain | Residue |
| F | MET1 |
| H | ASP85 |
| H | ALA87 |
| H | GLU120 |
| H | TRP123 |
Functional Information from PROSITE/UniProt
| site_id | PS01332 |
| Number of Residues | 19 |
| Details | HTH_RRF2_1 Rrf2-type HTH domain signature. LsraGLvrSvqGktGGYvL |
| Chain | Residue | Details |
| A | LEU47-LEU65 |
