6HRD

Crystal structure of M. tuberculosis FadB2 (Rv0468)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0019605	biological_process	butyrate metabolic process
A	0030497	biological_process	fatty acid elongation
A	0032787	biological_process	monocarboxylic acid metabolic process
A	0070403	molecular_function	NAD+ binding
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0019605	biological_process	butyrate metabolic process
B	0030497	biological_process	fatty acid elongation
B	0032787	biological_process	monocarboxylic acid metabolic process
B	0070403	molecular_function	NAD+ binding
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0019605	biological_process	butyrate metabolic process
C	0030497	biological_process	fatty acid elongation
C	0032787	biological_process	monocarboxylic acid metabolic process
C	0070403	molecular_function	NAD+ binding
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006635	biological_process	fatty acid beta-oxidation
D	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0019605	biological_process	butyrate metabolic process
D	0030497	biological_process	fatty acid elongation
D	0032787	biological_process	monocarboxylic acid metabolic process
D	0070403	molecular_function	NAD+ binding
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006629	biological_process	lipid metabolic process
E	0006631	biological_process	fatty acid metabolic process
E	0006635	biological_process	fatty acid beta-oxidation
E	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0019605	biological_process	butyrate metabolic process
E	0030497	biological_process	fatty acid elongation
E	0032787	biological_process	monocarboxylic acid metabolic process
E	0070403	molecular_function	NAD+ binding
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006629	biological_process	lipid metabolic process
F	0006631	biological_process	fatty acid metabolic process
F	0006635	biological_process	fatty acid beta-oxidation
F	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0019605	biological_process	butyrate metabolic process
F	0030497	biological_process	fatty acid elongation
F	0032787	biological_process	monocarboxylic acid metabolic process
F	0070403	molecular_function	NAD+ binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 301

Chain	Residue
A	HOH441
C	PRO258
C	HIS259
D	GLU257
D	PRO258
D	HIS259

---

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL C 301

Chain	Residue
B	GLU257
B	PRO258
B	HIS259
B	HOH351
C	HOH452
A	GLU257
A	PRO258
A	HIS259

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL E 301

Chain	Residue
E	PRO258
E	HIS259
E	HOH453
F	PRO258
F	HIS259

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Site: {"description":"Important for catalytic activity","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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