6HPT

Crystal structure of human Pif1 helicase, apoform.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000723	biological_process	telomere maintenance
A	0003678	molecular_function	DNA helicase activity
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue SO4 A 701

Chain	Residue
A	SER229
A	HOH1073
A	HOH1197
A	ALA230
A	GLY231
A	THR232
A	GLY233
A	LYS234
A	SER235
A	HOH983
A	HOH1052

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site_id	AC2
Number of Residues	11
Details	binding site for residue SO4 A 702

Chain	Residue
A	LYS414
A	VAL415
A	GLY416
A	ILE420
A	VAL421
A	ALA422
A	ARG592
A	ARG606
A	HOH855
A	HOH942
A	HOH996

---

site_id	AC3
Number of Residues	8
Details	binding site for residue SO4 A 703

Chain	Residue
A	HIS262
A	LYS485
A	ASN486
A	ASN495
A	HOH856
A	HOH883
A	HOH910
A	HOH1043

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	DNA_BIND: DNA_BIND => ECO:0000255|HAMAP-Rule:MF_03176

Chain	Residue	Details
A	GLN577-PHE596

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03176

Chain	Residue	Details
A	GLY228

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