6HPI

NMR structure of the pro-inflammatory cytokine interleukin-36alpha

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001819	biological_process	positive regulation of cytokine production
A	0002437	biological_process	inflammatory response to antigenic stimulus
A	0005125	molecular_function	cytokine activity
A	0005149	molecular_function	interleukin-1 receptor binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0010628	biological_process	positive regulation of gene expression
A	0019221	biological_process	cytokine-mediated signaling pathway
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0045087	biological_process	innate immune response
A	0071222	biological_process	cellular response to lipopolysaccharide

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: 3'-nitrotyrosine => ECO:0007744|PubMed:16777052

Chain	Residue	Details
A	TYR96

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