6HPI

NMR structure of the pro-inflammatory cytokine interleukin-36alpha

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001819	biological_process	positive regulation of cytokine production
A	0002376	biological_process	immune system process
A	0005125	molecular_function	cytokine activity
A	0005149	molecular_function	interleukin-1 receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0019221	biological_process	cytokine-mediated signaling pathway
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0045087	biological_process	innate immune response
A	0071222	biological_process	cellular response to lipopolysaccharide

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Propeptide: {"featureId":"PRO_0000430545","evidences":[{"source":"PubMed","id":"21965679","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"3'-nitrotyrosine","evidences":[{"source":"PubMed","id":"16777052","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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