6HPB

Crystal structure of the E.coli HicAB toxin-antitoxin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005515	molecular_function	protein binding
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006402	biological_process	mRNA catabolic process
A	0016787	molecular_function	hydrolase activity
A	0040008	biological_process	regulation of growth
A	0110001	cellular_component	toxin-antitoxin complex
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006950	biological_process	response to stress
B	0040008	biological_process	regulation of growth
B	0042802	molecular_function	identical protein binding
B	0110001	cellular_component	toxin-antitoxin complex
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004521	molecular_function	RNA endonuclease activity
C	0005515	molecular_function	protein binding
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006402	biological_process	mRNA catabolic process
C	0016787	molecular_function	hydrolase activity
C	0040008	biological_process	regulation of growth
C	0110001	cellular_component	toxin-antitoxin complex
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006950	biological_process	response to stress
D	0040008	biological_process	regulation of growth
D	0042802	molecular_function	identical protein binding
D	0110001	cellular_component	toxin-antitoxin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 101

Chain	Residue
A	HIS38
A	PRO39
A	CYS40
A	ASP41
B	LYS118
B	HOH301
B	HOH327

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site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 B 201

Chain	Residue
B	HOH304
B	MSE1
B	ARG2

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site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 D 201

Chain	Residue
B	ARG2
D	MSE1
D	ARG2
D	HOH304

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00257

Chain	Residue	Details
B	GLN93-ASN112
D	GLN93-ASN112

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