6HNV
Crystal structure of aminotransferase Aro9 from C. Albicans with ligands
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
| A | 0005575 | cellular_component | cellular_component |
| A | 0006571 | biological_process | L-tyrosine biosynthetic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0008793 | molecular_function | aromatic-amino-acid transaminase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009074 | biological_process | aromatic amino acid family catabolic process |
| A | 0009094 | biological_process | L-phenylalanine biosynthetic process |
| A | 0019477 | biological_process | L-lysine catabolic process |
| A | 0019878 | biological_process | L-lysine biosynthetic process via aminoadipic acid |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0047536 | molecular_function | 2-aminoadipate transaminase activity |
| B | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
| B | 0005575 | cellular_component | cellular_component |
| B | 0006571 | biological_process | L-tyrosine biosynthetic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0008793 | molecular_function | aromatic-amino-acid transaminase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009074 | biological_process | aromatic amino acid family catabolic process |
| B | 0009094 | biological_process | L-phenylalanine biosynthetic process |
| B | 0019477 | biological_process | L-lysine catabolic process |
| B | 0019878 | biological_process | L-lysine biosynthetic process via aminoadipic acid |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0047536 | molecular_function | 2-aminoadipate transaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue PLP A 601 |
| Chain | Residue |
| A | GLY165 |
| A | THR338 |
| A | SER340 |
| A | LYS341 |
| A | ARG348 |
| B | TYR130 |
| B | UN1602 |
| B | OOG605 |
| A | ALA166 |
| A | SER167 |
| A | PHE191 |
| A | ILE247 |
| A | ASN252 |
| A | ASP280 |
| A | PRO282 |
| A | TYR283 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue BCN A 602 |
| Chain | Residue |
| A | TYR423 |
| A | ASP432 |
| A | HOH730 |
| A | HOH745 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MPD A 603 |
| Chain | Residue |
| A | HIS6 |
| A | ASP274 |
| B | GLU501 |
| B | ARG508 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PHE A 604 |
| Chain | Residue |
| A | TYR130 |
| A | ALA131 |
| A | ARG371 |
| A | PPY605 |
| A | HOH701 |
| A | HOH715 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PPY A 605 |
| Chain | Residue |
| A | TYR130 |
| A | ARG371 |
| A | PHE604 |
| A | HOH701 |
| B | SER167 |
| B | ARG348 |
| B | PLP601 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue UN1 B 602 |
| Chain | Residue |
| A | SER167 |
| A | ARG348 |
| A | PLP601 |
| B | TYR130 |
| B | ARG371 |
| B | OOG605 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue BCN B 603 |
| Chain | Residue |
| A | PRO29 |
| A | GLU311 |
| A | GLU397 |
| B | GLN453 |
| B | LEU457 |
| B | GLU522 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue BCN B 604 |
| Chain | Residue |
| A | ASP213 |
| B | PHE212 |
| B | ASP213 |
| B | ASN214 |
| B | ASP429 |
| B | LYS442 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue OOG B 605 |
| Chain | Residue |
| A | PHE191 |
| A | PLP601 |
| B | TYR130 |
| B | ALA131 |
| B | ARG371 |
| B | UN1602 |
| site_id | AD1 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide PLP B 601 and LYS B 341 |
| Chain | Residue |
| A | GLY44 |
| A | TYR130 |
| A | PPY605 |
| B | GLY165 |
| B | ALA166 |
| B | SER167 |
| B | PHE191 |
| B | ASN252 |
| B | ASP280 |
| B | TYR283 |
| B | THR338 |
| B | PHE339 |
| B | SER340 |
| B | LEU342 |
| B | ARG348 |
| B | MET402 |
| B | MET437 |
