Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004674 | molecular_function | protein serine/threonine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue EDO A 401 |
Chain | Residue |
A | HIS276 |
A | SER277 |
A | LYS279 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue EDO A 402 |
Chain | Residue |
A | ASP25 |
A | TYR26 |
A | GLU27 |
A | HOH568 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue EDO A 403 |
Chain | Residue |
A | ARG107 |
A | SO4409 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue CL A 404 |
Chain | Residue |
A | GLU86 |
A | ARG89 |
B | HIS236 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 405 |
Chain | Residue |
A | LYS77 |
A | ARG80 |
A | ARG155 |
A | ASN189 |
A | VAL192 |
A | HOH529 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 406 |
Chain | Residue |
A | LYS279 |
A | ARG280 |
A | ARG283 |
A | HOH607 |
B | HOH557 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 407 |
Chain | Residue |
A | ARG191 |
A | LYS198 |
A | ASN238 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 408 |
Chain | Residue |
A | TRP33 |
A | LYS75 |
A | LYS102 |
A | HOH509 |
A | HOH531 |
A | HOH589 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 409 |
Chain | Residue |
A | LYS75 |
A | LYS102 |
A | EDO403 |
B | LYS74 |
site_id | AD1 |
Number of Residues | 13 |
Details | binding site for residue FXB A 410 |
Chain | Residue |
A | GLY48 |
A | VAL53 |
A | VAL66 |
A | LYS68 |
A | PHE113 |
A | GLU114 |
A | VAL116 |
A | ASN118 |
A | MET163 |
A | ILE174 |
A | ASP175 |
A | HOH504 |
A | HOH580 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue EDO B 401 |
Chain | Residue |
B | TRP24 |
B | ASP25 |
B | TYR26 |
B | GLU27 |
B | LYS44 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue EDO B 402 |
Chain | Residue |
A | LYS75 |
B | LYS74 |
B | LYS75 |
B | LYS76 |
site_id | AD4 |
Number of Residues | 7 |
Details | binding site for residue EDO B 403 |
Chain | Residue |
A | SER277 |
A | ARG278 |
A | HOH587 |
B | GLU252 |
B | ARG278 |
B | HOH565 |
B | HOH583 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue SO4 B 404 |
Chain | Residue |
B | LYS77 |
B | ARG80 |
B | ARG155 |
B | ASN189 |
B | HOH551 |
site_id | AD6 |
Number of Residues | 6 |
Details | binding site for residue SO4 B 405 |
Chain | Residue |
B | ARG275 |
B | HIS276 |
B | SER277 |
B | LYS279 |
B | HOH503 |
B | HOH508 |
site_id | AD7 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 406 |
Chain | Residue |
B | ARG191 |
B | LYS198 |
B | ASN238 |
site_id | AD8 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 407 |
Chain | Residue |
B | LYS75 |
B | HOH575 |
B | HOH649 |
site_id | AD9 |
Number of Residues | 6 |
Details | binding site for residue SO4 B 408 |
Chain | Residue |
A | ARG47 |
A | LYS74 |
A | LYS76 |
B | LYS75 |
B | LYS102 |
B | ARG107 |
site_id | AE1 |
Number of Residues | 4 |
Details | binding site for residue NA B 409 |
Chain | Residue |
B | PHE232 |
B | HOH556 |
B | HOH628 |
B | HOH687 |
site_id | AE2 |
Number of Residues | 13 |
Details | binding site for residue FXB B 410 |
Chain | Residue |
B | GLU114 |
B | VAL116 |
B | MET163 |
B | ILE174 |
B | ASP175 |
B | HOH523 |
B | GLY48 |
B | SER51 |
B | VAL53 |
B | VAL66 |
B | LYS68 |
B | ILE95 |
B | PHE113 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
Chain | Residue | Details |
A | LEU45-LYS68 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
Chain | Residue | Details |
A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | ASP156 | |
B | ASP156 | |
Chain | Residue | Details |
A | LEU45 | |
A | LYS68 | |
B | LEU45 | |
B | LYS68 | |