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6HGE

Crystal structure of Alpha1-antichymotrypsin variant NewBG-I in the uncleaved S-conformation

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0006953biological_processacute-phase response
A0006954biological_processinflammatory response
A0019216biological_processregulation of lipid metabolic process
A0030277biological_processmaintenance of gastrointestinal epithelium
A0030414molecular_functionpeptidase inhibitor activity
A0031012cellular_componentextracellular matrix
A0031093cellular_componentplatelet alpha granule lumen
A0034097biological_processresponse to cytokine
A0034774cellular_componentsecretory granule lumen
A0035578cellular_componentazurophil granule lumen
A0070062cellular_componentextracellular exosome
A0072562cellular_componentblood microparticle
B0003677molecular_functionDNA binding
B0004867molecular_functionserine-type endopeptidase inhibitor activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0006953biological_processacute-phase response
B0006954biological_processinflammatory response
B0019216biological_processregulation of lipid metabolic process
B0030277biological_processmaintenance of gastrointestinal epithelium
B0030414molecular_functionpeptidase inhibitor activity
B0031012cellular_componentextracellular matrix
B0031093cellular_componentplatelet alpha granule lumen
B0034097biological_processresponse to cytokine
B0034774cellular_componentsecretory granule lumen
B0035578cellular_componentazurophil granule lumen
B0070062cellular_componentextracellular exosome
B0072562cellular_componentblood microparticle
C0003677molecular_functionDNA binding
C0004867molecular_functionserine-type endopeptidase inhibitor activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005634cellular_componentnucleus
C0006953biological_processacute-phase response
C0006954biological_processinflammatory response
C0019216biological_processregulation of lipid metabolic process
C0030277biological_processmaintenance of gastrointestinal epithelium
C0030414molecular_functionpeptidase inhibitor activity
C0031012cellular_componentextracellular matrix
C0031093cellular_componentplatelet alpha granule lumen
C0034097biological_processresponse to cytokine
C0034774cellular_componentsecretory granule lumen
C0035578cellular_componentazurophil granule lumen
C0070062cellular_componentextracellular exosome
C0072562cellular_componentblood microparticle
D0003677molecular_functionDNA binding
D0004867molecular_functionserine-type endopeptidase inhibitor activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0006953biological_processacute-phase response
D0006954biological_processinflammatory response
D0019216biological_processregulation of lipid metabolic process
D0030277biological_processmaintenance of gastrointestinal epithelium
D0030414molecular_functionpeptidase inhibitor activity
D0031012cellular_componentextracellular matrix
D0031093cellular_componentplatelet alpha granule lumen
D0034097biological_processresponse to cytokine
D0034774cellular_componentsecretory granule lumen
D0035578cellular_componentazurophil granule lumen
D0070062cellular_componentextracellular exosome
D0072562cellular_componentblood microparticle
Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. VRFNRPFLMiI
ChainResidueDetails
AVAL370-ILE380
DVAL370-ILE380
BVAL370-ILE380
CVAL370-ILE380

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsDNA_BIND:
ChainResidueDetails
DMLY212-MLY214

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Reactive bond
ChainResidueDetails
DLEU360

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952
ChainResidueDetails
DASN10
DASN163

site_idSWS_FT_FI4
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218
ChainResidueDetails
DASN70

site_idSWS_FT_FI5
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218
ChainResidueDetails
DASN83

site_idSWS_FT_FI6
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218
ChainResidueDetails
DASN104
DASN248

237423

PDB entries from 2025-06-11

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