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6HE4

AAA-ATPase ring of PAN-proteasomes

Functional Information from GO Data
ChainGOidnamespacecontents
H0005524molecular_functionATP binding
H0016887molecular_functionATP hydrolysis activity
I0005524molecular_functionATP binding
I0016887molecular_functionATP hydrolysis activity
J0005524molecular_functionATP binding
J0016887molecular_functionATP hydrolysis activity
K0005524molecular_functionATP binding
K0016887molecular_functionATP hydrolysis activity
L0005524molecular_functionATP binding
L0016887molecular_functionATP hydrolysis activity
M0005524molecular_functionATP binding
M0016887molecular_functionATP hydrolysis activity
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue ATP H 401
ChainResidue
HILE143
HILE320
HHIS324
HGLY348
HALA349
HLYS352
HMG402
ILYS176
ILEU269
IALA296
IARG299
HGLY144
IARG302
HGLY185
HTHR186
HGLY187
HLYS188
HTHR189
HLEU190
HASN288

site_idAC2
Number of Residues3
Detailsbinding site for residue MG H 402
ChainResidue
HTHR189
HATP401
IARG302

site_idAC3
Number of Residues17
Detailsbinding site for residue ATP I 401
ChainResidue
IPRO184
IGLY185
ITHR186
IGLY187
ILYS188
ITHR189
ILEU190
IASN288
IILE320
IHIS324
IALA349
IMG402
JASP273
JGLY274
JALA296
JARG299
JARG302

site_idAC4
Number of Residues3
Detailsbinding site for residue MG I 402
ChainResidue
ITHR189
IATP401
JARG302

site_idAC5
Number of Residues18
Detailsbinding site for residue ATP K 401
ChainResidue
KPRO184
KGLY185
KTHR186
KGLY187
KLYS188
KTHR189
KLEU190
KASN288
KILE320
KHIS324
KGLY348
KALA349
KLYS352
KMG402
LASP273
LALA296
LARG299
LARG302

site_idAC6
Number of Residues3
Detailsbinding site for residue MG K 402
ChainResidue
KTHR189
KGLU242
KATP401

site_idAC7
Number of Residues12
Detailsbinding site for residue ADP L 401
ChainResidue
LGLY185
LTHR186
LGLY187
LLYS188
LTHR189
LLEU190
LILE320
LHIS324
LGLY348
LALA349
LMG402
MGLU173

site_idAC8
Number of Residues2
Detailsbinding site for residue MG L 402
ChainResidue
LTHR189
LADP401

site_idAC9
Number of Residues19
Detailsbinding site for residue ATP J 401
ChainResidue
JGLY144
JPRO184
JGLY185
JTHR186
JGLY187
JLYS188
JTHR189
JLEU190
JGLU242
JILE320
JHIS324
JGLY348
JALA349
JLYS352
JMG402
KLYS176
KASP273
KARG299
KARG302

site_idAD1
Number of Residues2
Detailsbinding site for residue MG J 402
ChainResidue
JTHR189
JATP401

Functional Information from PROSITE/UniProt
site_idPS00674
Number of Residues19
DetailsAAA AAA-protein family signature. VkVIgATNridiLDpAIl.R
ChainResidueDetails
HVAL281-ARG299

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00553
ChainResidueDetails
HGLY185
MHIS324
JGLY185
JHIS324
HHIS324
IGLY185
IHIS324
KGLY185
KHIS324
LGLY185
LHIS324
MGLY185

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PDB entries from 2024-11-06

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