Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue C2E A 401 |
| Chain | Residue |
| A | LYS215 |
| A | HOH561 |
| A | HOH598 |
| A | HOH602 |
| A | HOH609 |
| A | HOH642 |
| B | ARG218 |
| B | ASP221 |
| B | THR242 |
| B | ARG249 |
| B | HOH504 |
| A | LEU216 |
| B | HOH507 |
| A | ILE217 |
| A | ARG218 |
| A | SER219 |
| A | ARG249 |
| A | C2E402 |
| A | HOH517 |
| A | HOH539 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue C2E A 402 |
| Chain | Residue |
| A | ILE217 |
| A | ARG218 |
| A | ASP221 |
| A | THR242 |
| A | VAL246 |
| A | ARG249 |
| A | C2E401 |
| A | HOH502 |
| A | HOH547 |
| A | HOH577 |
| A | HOH578 |
| A | HOH604 |
| A | HOH609 |
| A | HOH652 |
| A | HOH667 |
| B | LYS215 |
| B | LEU216 |
| B | ILE217 |
| B | ARG218 |
| B | SER219 |
| B | ARG249 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | PRO166 |
| A | GLU283 |
| A | TRP284 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | ARG76 |
| B | ASP56 |
| B | CL403 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 401 |
| Chain | Residue |
| B | ARG61 |
| B | ARG76 |
| B | HOH633 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | HIS188 |
| B | ARG303 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 403 |
| Chain | Residue |
| A | ARG76 |
| A | SER77 |
| A | CL404 |
| B | LYS80 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | SER240 |
| B | THR276 |
| B | LEU278 |
| B | HOH517 |
| B | HOH540 |
| B | HOH588 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | ASP202 |
| B | ARG225 |
| B | HOH509 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | ILE100 |
| B | LYS121 |
| B | HOH599 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 407 |
| Chain | Residue |
| B | GLY154 |
| B | THR214 |
