Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | HIS148 |
| A | ALA315 |
| A | HOH641 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | ARG155 |
| A | ASN189 |
| A | HOH516 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | ARG244 |
| A | LYS229 |
| A | PHE232 |
| A | HIS234 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | LYS122 |
| A | PRO159 |
| A | HIS160 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | GLU187 |
| B | ARG43 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue FXB A 406 |
| Chain | Residue |
| A | GLY46 |
| A | GLY48 |
| A | VAL53 |
| A | VAL66 |
| A | LYS68 |
| A | ILE95 |
| A | ASN118 |
| A | MET163 |
| A | ILE174 |
| A | ASP175 |
| A | HOH502 |
| A | HOH699 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 407 |
| Chain | Residue |
| A | LYS64 |
| A | GLU114 |
| A | HOH519 |
| A | HOH717 |
| A | HOH739 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 401 |
| Chain | Residue |
| B | HIS148 |
| B | ALA315 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | ARG155 |
| B | ASN189 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 403 |
| Chain | Residue |
| B | LYS229 |
| B | PHE232 |
| B | HIS234 |
| B | ARG244 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 404 |
| Chain | Residue |
| B | LYS122 |
| B | PRO159 |
| B | HIS160 |
| B | HOH748 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 405 |
| Chain | Residue |
| B | HOH580 |
| B | HOH604 |
| B | HOH671 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue FXB B 406 |
| Chain | Residue |
| B | GLY46 |
| B | GLY48 |
| B | VAL66 |
| B | LYS68 |
| B | ILE95 |
| B | ASN118 |
| B | MET163 |
| B | ILE174 |
| B | ASP175 |
| B | HOH512 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 407 |
| Chain | Residue |
| B | LYS64 |
| B | GLU114 |
| B | HOH545 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 408 |
| Chain | Residue |
| A | HOH537 |
| A | HOH688 |
| B | THR60 |
| B | HOH553 |
| B | HOH763 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 570 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
