6HAC

Crystal structure of [Fe]-hydrogenase (Hmd) holoenzyme from Methanococcus aeolicus (open form)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004735	molecular_function	pyrroline-5-carboxylate reductase activity
A	0006730	biological_process	one-carbon metabolic process
A	0015948	biological_process	methanogenesis
A	0016491	molecular_function	oxidoreductase activity
A	0019386	biological_process	methanogenesis, from carbon dioxide
A	0047068	molecular_function	N5,N10-methenyltetrahydromethanopterin hydrogenase activity
A	0055129	biological_process	L-proline biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	binding site for residue FE9 A 401

Chain	Residue
A	LEU6
A	PRO115
A	CYS118
A	ASP135
A	TRP148
A	LEU149
A	PRO150
A	ILE158
A	ALA175
A	CYS176
A	THR177
A	GLY7
A	HIS201
A	PRO202
A	GLY203
A	CYS204
A	VAL205
A	PRO206
A	HOH504
A	HOH517
A	HOH542
A	HOH543
A	GLY9
A	HOH548
A	CYS10
A	SER13
A	SER63
A	ASP64
A	PRO65
A	PRO114

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site_id	AC2
Number of Residues	4
Details	binding site for residue 1PE A 402

Chain	Residue
A	CYS17
A	ILE19
A	ASP102
A	SER320

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site_id	AC3
Number of Residues	4
Details	binding site for residue GOL A 403

Chain	Residue
A	ASP77
A	LYS107
A	ASN273
A	HOH560

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site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 404

Chain	Residue
A	GLU295
A	ARG298
A	ARG298
A	HOH532

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site_id	AC5
Number of Residues	6
Details	binding site for residue NA A 405

Chain	Residue
A	PRO325
A	LEU326
A	SER327
A	GLU328
A	LEU329
A	HOH605

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