6H6V
Structure of the UbiD-class enzyme HmfF from Pelotomaculum thermopropionicum in complex with FMN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006744 | biological_process | ubiquinone biosynthetic process |
| A | 0008694 | molecular_function | 4-hydroxy-3-polyprenylbenzoate decarboxylase activity |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0018799 | molecular_function | 4-hydroxybenzoate decarboxylase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006744 | biological_process | ubiquinone biosynthetic process |
| B | 0008694 | molecular_function | 4-hydroxy-3-polyprenylbenzoate decarboxylase activity |
| B | 0009636 | biological_process | response to toxic substance |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0018799 | molecular_function | 4-hydroxybenzoate decarboxylase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006744 | biological_process | ubiquinone biosynthetic process |
| C | 0008694 | molecular_function | 4-hydroxy-3-polyprenylbenzoate decarboxylase activity |
| C | 0009636 | biological_process | response to toxic substance |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0018799 | molecular_function | 4-hydroxybenzoate decarboxylase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006744 | biological_process | ubiquinone biosynthetic process |
| D | 0008694 | molecular_function | 4-hydroxy-3-polyprenylbenzoate decarboxylase activity |
| D | 0009636 | biological_process | response to toxic substance |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0018799 | molecular_function | 4-hydroxybenzoate decarboxylase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006744 | biological_process | ubiquinone biosynthetic process |
| E | 0008694 | molecular_function | 4-hydroxy-3-polyprenylbenzoate decarboxylase activity |
| E | 0009636 | biological_process | response to toxic substance |
| E | 0016831 | molecular_function | carboxy-lyase activity |
| E | 0018799 | molecular_function | 4-hydroxybenzoate decarboxylase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006744 | biological_process | ubiquinone biosynthetic process |
| F | 0008694 | molecular_function | 4-hydroxy-3-polyprenylbenzoate decarboxylase activity |
| F | 0009636 | biological_process | response to toxic substance |
| F | 0016831 | molecular_function | carboxy-lyase activity |
| F | 0018799 | molecular_function | 4-hydroxybenzoate decarboxylase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue FMN A 501 |
| Chain | Residue |
| A | ASN147 |
| A | SER200 |
| A | GLN201 |
| A | GLU210 |
| A | HIS296 |
| A | K502 |
| A | MN503 |
| A | HOH603 |
| A | HOH616 |
| A | HOH619 |
| A | HOH628 |
| A | SER149 |
| A | ILE150 |
| A | HIS151 |
| A | ARG152 |
| A | LEU164 |
| A | LEU166 |
| A | ARG168 |
| A | HIS169 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue K A 502 |
| Chain | Residue |
| A | VAL148 |
| A | SER200 |
| A | ALA202 |
| A | GLU210 |
| A | FMN501 |
| A | MN503 |
| A | HOH619 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 503 |
| Chain | Residue |
| A | ASN147 |
| A | HIS169 |
| A | GLU210 |
| A | FMN501 |
| A | K502 |
| A | HOH619 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 504 |
| Chain | Residue |
| A | ARG385 |
| A | ASP391 |
| A | ASP418 |
| A | THR420 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | binding site for residue FMN B 501 |
| Chain | Residue |
| B | ASN147 |
| B | SER149 |
| B | ILE150 |
| B | HIS151 |
| B | ARG152 |
| B | LEU164 |
| B | LEU166 |
| B | ARG168 |
| B | HIS169 |
| B | SER200 |
| B | GLN201 |
| B | GLU210 |
| B | HIS296 |
| B | K502 |
| B | MN503 |
| B | HOH607 |
| B | HOH608 |
| B | HOH621 |
| B | HOH624 |
| B | HOH641 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue K B 502 |
| Chain | Residue |
| B | VAL148 |
| B | SER200 |
| B | ALA202 |
| B | GLU210 |
| B | FMN501 |
| B | MN503 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue MN B 503 |
| Chain | Residue |
| B | ASN147 |
| B | HIS169 |
| B | GLU210 |
| B | FMN501 |
| B | K502 |
| B | HOH624 |
| B | HOH625 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 504 |
| Chain | Residue |
| B | ARG385 |
| B | ASP391 |
| B | ASP418 |
| B | THR420 |
| B | HOH648 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | binding site for residue FMN C 501 |
| Chain | Residue |
| C | ASN147 |
| C | SER149 |
| C | ILE150 |
| C | HIS151 |
| C | ARG152 |
| C | LEU164 |
| C | LEU166 |
| C | ARG168 |
| C | HIS169 |
| C | SER200 |
| C | GLN201 |
| C | GLU210 |
| C | HIS296 |
| C | K502 |
| C | MN503 |
| C | HOH606 |
| C | HOH621 |
| C | HOH624 |
| C | HOH626 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue K C 502 |
| Chain | Residue |
| C | HOH621 |
| C | VAL148 |
| C | SER200 |
| C | ALA202 |
| C | GLU210 |
| C | FMN501 |
| C | MN503 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MN C 503 |
| Chain | Residue |
| C | ASN147 |
| C | HIS169 |
| C | GLU210 |
| C | FMN501 |
| C | K502 |
| C | HOH621 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 504 |
| Chain | Residue |
| C | ARG385 |
| C | ASP391 |
| C | ASP418 |
| C | THR420 |
| C | HOH602 |
| site_id | AD4 |
| Number of Residues | 21 |
| Details | binding site for residue FMN D 501 |
| Chain | Residue |
| D | ASN147 |
| D | SER149 |
| D | ILE150 |
| D | HIS151 |
| D | ARG152 |
| D | LEU164 |
| D | LEU166 |
| D | ARG168 |
| D | HIS169 |
| D | SER200 |
| D | GLN201 |
| D | GLU210 |
| D | HIS296 |
| D | LEU299 |
| D | K502 |
| D | MN503 |
| D | HOH607 |
| D | HOH608 |
| D | HOH625 |
| D | HOH629 |
| D | HOH630 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue K D 502 |
| Chain | Residue |
| D | VAL148 |
| D | SER200 |
| D | ALA202 |
| D | GLU210 |
| D | FMN501 |
| D | MN503 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue MN D 503 |
| Chain | Residue |
| D | ASN147 |
| D | HIS169 |
| D | GLU210 |
| D | FMN501 |
| D | K502 |
| D | HOH610 |
| D | HOH629 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 504 |
| Chain | Residue |
| D | ARG385 |
| D | ASP391 |
| D | ASP418 |
| D | THR420 |
| D | HOH624 |
| site_id | AD8 |
| Number of Residues | 20 |
| Details | binding site for residue FMN E 501 |
| Chain | Residue |
| E | ASN147 |
| E | VAL148 |
| E | SER149 |
| E | ILE150 |
| E | HIS151 |
| E | ARG152 |
| E | LEU164 |
| E | LEU166 |
| E | ARG168 |
| E | HIS169 |
| E | SER200 |
| E | GLN201 |
| E | GLU210 |
| E | HIS296 |
| E | K502 |
| E | MN503 |
| E | HOH605 |
| E | HOH606 |
| E | HOH625 |
| E | HOH627 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue K E 502 |
| Chain | Residue |
| E | VAL148 |
| E | SER200 |
| E | ALA202 |
| E | GLU210 |
| E | FMN501 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue MN E 503 |
| Chain | Residue |
| E | ASN147 |
| E | HIS169 |
| E | GLU210 |
| E | FMN501 |
| E | HOH618 |
| E | HOH627 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CA E 504 |
| Chain | Residue |
| E | ARG385 |
| E | ASP391 |
| E | ASP418 |
| E | THR420 |
| E | HOH612 |
| site_id | AE3 |
| Number of Residues | 18 |
| Details | binding site for residue FMN F 501 |
| Chain | Residue |
| F | ASN147 |
| F | VAL148 |
| F | SER149 |
| F | ILE150 |
| F | HIS151 |
| F | ARG152 |
| F | LEU164 |
| F | LEU166 |
| F | ARG168 |
| F | HIS169 |
| F | SER200 |
| F | GLN201 |
| F | GLU210 |
| F | HIS296 |
| F | K502 |
| F | MN503 |
| F | HOH604 |
| F | HOH618 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue K F 502 |
| Chain | Residue |
| F | VAL148 |
| F | SER200 |
| F | ALA202 |
| F | GLU210 |
| F | FMN501 |
| F | MN503 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue MN F 503 |
| Chain | Residue |
| F | ASN147 |
| F | HIS169 |
| F | GLU210 |
| F | FMN501 |
| F | K502 |
| F | HOH608 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue CA F 504 |
| Chain | Residue |
| F | ARG385 |
| F | ASP391 |
| F | ASP418 |
| F | THR420 |
