6H6B

Structure of alpha-synuclein fibrils

Replaces:  6FLT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0014059	biological_process	regulation of dopamine secretion
B	0005737	cellular_component	cytoplasm
B	0014059	biological_process	regulation of dopamine secretion
C	0005737	cellular_component	cytoplasm
C	0014059	biological_process	regulation of dopamine secretion
D	0005737	cellular_component	cytoplasm
D	0014059	biological_process	regulation of dopamine secretion
E	0005737	cellular_component	cytoplasm
E	0014059	biological_process	regulation of dopamine secretion
F	0005737	cellular_component	cytoplasm
F	0014059	biological_process	regulation of dopamine secretion
G	0005737	cellular_component	cytoplasm
G	0014059	biological_process	regulation of dopamine secretion
H	0005737	cellular_component	cytoplasm
H	0014059	biological_process	regulation of dopamine secretion
I	0005737	cellular_component	cytoplasm
I	0014059	biological_process	regulation of dopamine secretion
J	0005737	cellular_component	cytoplasm
J	0014059	biological_process	regulation of dopamine secretion

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	ASP2
E	HIS50
F	ASP2
F	HIS50
G	ASP2
G	HIS50
H	ASP2
H	HIS50
I	ASP2
I	HIS50
J	ASP2
A	HIS50
J	HIS50
B	ASP2
B	HIS50
C	ASP2
C	HIS50
D	ASP2
D	HIS50
E	ASP2

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:22407793

Chain	Residue	Details
A	MET1
J	MET1
B	MET1
C	MET1
D	MET1
E	MET1
F	MET1
G	MET1
H	MET1
I	MET1

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:10617630

Chain	Residue	Details
A	SER87
J	SER87
B	SER87
C	SER87
D	SER87
E	SER87
F	SER87
G	SER87
H	SER87
I	SER87

---