Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6H65

Crystal structure of the branched-chain-amino-acid aminotransferase from Haliangium ochraceum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid transaminase activity
A	0008483	molecular_function	transaminase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0019752	biological_process	carboxylic acid metabolic process
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
A	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
A	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid transaminase activity
B	0008483	molecular_function	transaminase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0019752	biological_process	carboxylic acid metabolic process
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
B	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
B	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid transaminase activity
C	0008483	molecular_function	transaminase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0019752	biological_process	carboxylic acid metabolic process
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
C	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
C	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
D	0003824	molecular_function	catalytic activity
D	0004084	molecular_function	branched-chain-amino-acid transaminase activity
D	0008483	molecular_function	transaminase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009081	biological_process	branched-chain amino acid metabolic process
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0009098	biological_process	L-leucine biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0019752	biological_process	carboxylic acid metabolic process
D	0046394	biological_process	carboxylic acid biosynthetic process
D	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
D	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
D	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
E	0003824	molecular_function	catalytic activity
E	0004084	molecular_function	branched-chain-amino-acid transaminase activity
E	0008483	molecular_function	transaminase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009081	biological_process	branched-chain amino acid metabolic process
E	0009082	biological_process	branched-chain amino acid biosynthetic process
E	0009097	biological_process	isoleucine biosynthetic process
E	0009098	biological_process	L-leucine biosynthetic process
E	0009099	biological_process	L-valine biosynthetic process
E	0019752	biological_process	carboxylic acid metabolic process
E	0046394	biological_process	carboxylic acid biosynthetic process
E	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
E	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
E	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
F	0003824	molecular_function	catalytic activity
F	0004084	molecular_function	branched-chain-amino-acid transaminase activity
F	0008483	molecular_function	transaminase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009081	biological_process	branched-chain amino acid metabolic process
F	0009082	biological_process	branched-chain amino acid biosynthetic process
F	0009097	biological_process	isoleucine biosynthetic process
F	0009098	biological_process	L-leucine biosynthetic process
F	0009099	biological_process	L-valine biosynthetic process
F	0019752	biological_process	carboxylic acid metabolic process
F	0046394	biological_process	carboxylic acid biosynthetic process
F	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
F	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
F	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue PLP A 401

Chain	Residue
A	ARG69
A	VAL228
A	THR229
A	GLY265
A	THR266
A	ARG156
A	LYS167
A	TYR172
A	GLU201
A	PRO203
A	ALA205
A	LEU225
A	SER227

site_id	AC2
Number of Residues	16
Details	binding site for Di-peptide PLP B 401 and LYS B 167

Chain	Residue
B	LEU43
B	PHE44
B	ARG69
B	ARG156
B	ILE166
B	ILE168
B	TYR172
B	GLU201
B	PRO203
B	ALA205
B	LEU225
B	SER227
B	VAL228
B	THR229
B	GLY265
B	THR266

site_id	AC3
Number of Residues	16
Details	binding site for Di-peptide PLP C 401 and LYS C 167

Chain	Residue
C	LEU43
C	PHE44
C	ARG69
C	ARG156
C	ILE166
C	ILE168
C	TYR172
C	GLU201
C	PRO203
C	ALA205
C	LEU225
C	SER227
C	VAL228
C	THR229
C	GLY265
C	THR266

site_id	AC4
Number of Residues	16
Details	binding site for Di-peptide PLP D 401 and LYS D 167

Chain	Residue
D	LEU43
D	PHE44
D	ARG69
D	ARG156
D	ILE166
D	ILE168
D	TYR172
D	GLU201
D	PRO203
D	ALA205
D	LEU225
D	SER227
D	VAL228
D	THR229
D	GLY265
D	THR266

site_id	AC5
Number of Residues	15
Details	binding site for Di-peptide PLP E 401 and LYS E 167

Chain	Residue
E	LEU43
E	PHE44
E	ARG69
E	ILE166
E	ILE168
E	TYR172
E	GLU201
E	PRO203
E	ALA205
E	LEU225
E	SER227
E	VAL228
E	THR229
E	GLY265
E	THR266

site_id	AC6
Number of Residues	17
Details	binding site for Di-peptide PLP F 401 and LYS F 167

Chain	Residue
F	LEU43
F	PHE44
F	ARG69
F	ARG156
F	ILE166
F	ILE168
F	TYR172
F	GLU201
F	PRO203
F	ALA205
F	LEU225
F	SER227
F	VAL228
F	THR229
F	GLY265
F	THR266
F	HOH503

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)