6H60
pseudo-atomic structural model of the E3BP component of the human pyruvate dehydrogenase multienzyme complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0006086 | biological_process | acetyl-CoA biosynthetic process from pyruvate |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0034604 | molecular_function | pyruvate dehydrogenase (NAD+) activity |
| A | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| A | 1990204 | cellular_component | oxidoreductase complex |
Functional Information from PROSITE/UniProt
| site_id | PS00189 |
| Number of Residues | 30 |
| Details | LIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GeaVsagDALceIETdKAVvtLdasddGiL |
| Chain | Residue | Details |
| A | GLY-187-LEU-158 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-lipoyllysine => ECO:0000255|PROSITE-ProRule:PRU01066, ECO:0000269|PubMed:25525879 |
| Chain | Residue | Details |
| A | LYS-171 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS-74 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER-72 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q8BKZ9 |
| Chain | Residue | Details |
| A | LYS126 |
