6H5O

Crystal structure of PBP2a from MRSA in complex with piperacillin at active site.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008658	molecular_function	penicillin binding
A	0016020	cellular_component	membrane
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
A	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity
B	0005886	cellular_component	plasma membrane
B	0008658	molecular_function	penicillin binding
B	0016020	cellular_component	membrane
B	0046677	biological_process	response to antibiotic
B	0071555	biological_process	cell wall organization
B	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue JPP A 701

Chain	Residue
A	GLY402
A	MET641
A	ALA642
A	SER403
A	ASN464
A	TYR519
A	GLN521
A	SER598
A	GLY599
A	THR600
A	GLU602

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site_id	AC2
Number of Residues	4
Details	binding site for residue CD A 702

Chain	Residue
A	GLY135
A	HIS311
A	CD703
B	ASP209

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CD A 703

Chain	Residue
A	GLY135
A	HIS311
A	CD702
B	ASP209

---

site_id	AC4
Number of Residues	5
Details	binding site for residue CD A 704

Chain	Residue
A	HIS143
A	GLU145
A	CD705
A	CD708
B	GLU145

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CD A 705

Chain	Residue
A	HIS143
A	GLU145
A	CD704
B	GLU145

---

site_id	AC6
Number of Residues	4
Details	binding site for residue CD A 706

Chain	Residue
A	ILE144
A	GLU145
A	CD708
B	HOH812

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CD A 707

Chain	Residue
A	ASP386

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CD A 708

Chain	Residue
A	GLU145
A	CD704
A	CD706
B	HIS143
B	GLU145
B	HOH812

---

site_id	AC9
Number of Residues	4
Details	binding site for residue CD A 709

Chain	Residue
A	ASP209
B	GLY135
B	HIS311
B	CD702

---

site_id	AD1
Number of Residues	4
Details	binding site for residue CD B 702

Chain	Residue
A	GLN207
A	CD709
B	GLY135
B	HIS311

---

site_id	AD2
Number of Residues	15
Details	binding site for Di-peptide JPP B 701 and SER B 403

Chain	Residue
B	PRO401
B	GLY402
B	THR404
B	GLN405
B	LYS406
B	SER462
B	ASN464
B	TYR519
B	GLN521
B	SER598
B	GLY599
B	THR600
B	ALA601
B	GLU602
B	ALA642

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