6H5I

Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0004322	molecular_function	ferroxidase activity
Aa	0005506	molecular_function	iron ion binding
Aa	0005515	molecular_function	protein binding
Aa	0005576	cellular_component	extracellular region
Aa	0005634	cellular_component	nucleus
Aa	0005737	cellular_component	cytoplasm
Aa	0005764	cellular_component	lysosome
Aa	0005776	cellular_component	autophagosome
Aa	0005829	cellular_component	cytosol
Aa	0006826	biological_process	iron ion transport
Aa	0006879	biological_process	intracellular iron ion homeostasis
Aa	0006955	biological_process	immune response
Aa	0008198	molecular_function	ferrous iron binding
Aa	0008199	molecular_function	ferric iron binding
Aa	0008285	biological_process	negative regulation of cell population proliferation
Aa	0016491	molecular_function	oxidoreductase activity
Aa	0031410	cellular_component	cytoplasmic vesicle
Aa	0042802	molecular_function	identical protein binding
Aa	0044754	cellular_component	autolysosome
Aa	0046872	molecular_function	metal ion binding
Aa	0048147	biological_process	negative regulation of fibroblast proliferation
Aa	0070062	cellular_component	extracellular exosome
Aa	0070288	cellular_component	ferritin complex
Aa	0110076	biological_process	negative regulation of ferroptosis
Aa	0140315	molecular_function	iron ion sequestering activity
Aa	1904724	cellular_component	tertiary granule lumen
Aa	1904813	cellular_component	ficolin-1-rich granule lumen
Ab	0004998	molecular_function	transferrin receptor activity
Ab	0033572	biological_process	transferrin transport
Ac	0004322	molecular_function	ferroxidase activity
Ac	0005506	molecular_function	iron ion binding
Ac	0005515	molecular_function	protein binding
Ac	0005576	cellular_component	extracellular region
Ac	0005634	cellular_component	nucleus
Ac	0005737	cellular_component	cytoplasm
Ac	0005764	cellular_component	lysosome
Ac	0005776	cellular_component	autophagosome
Ac	0005829	cellular_component	cytosol
Ac	0006826	biological_process	iron ion transport
Ac	0006879	biological_process	intracellular iron ion homeostasis
Ac	0006955	biological_process	immune response
Ac	0008198	molecular_function	ferrous iron binding
Ac	0008199	molecular_function	ferric iron binding
Ac	0008285	biological_process	negative regulation of cell population proliferation
Ac	0016491	molecular_function	oxidoreductase activity
Ac	0031410	cellular_component	cytoplasmic vesicle
Ac	0042802	molecular_function	identical protein binding
Ac	0044754	cellular_component	autolysosome
Ac	0046872	molecular_function	metal ion binding
Ac	0048147	biological_process	negative regulation of fibroblast proliferation
Ac	0070062	cellular_component	extracellular exosome
Ac	0070288	cellular_component	ferritin complex
Ac	0110076	biological_process	negative regulation of ferroptosis
Ac	0140315	molecular_function	iron ion sequestering activity
Ac	1904724	cellular_component	tertiary granule lumen
Ac	1904813	cellular_component	ficolin-1-rich granule lumen
Ad	0004322	molecular_function	ferroxidase activity
Ad	0005506	molecular_function	iron ion binding
Ad	0005515	molecular_function	protein binding
Ad	0005576	cellular_component	extracellular region
Ad	0005634	cellular_component	nucleus
Ad	0005737	cellular_component	cytoplasm
Ad	0005764	cellular_component	lysosome
Ad	0005776	cellular_component	autophagosome
Ad	0005829	cellular_component	cytosol
Ad	0006826	biological_process	iron ion transport
Ad	0006879	biological_process	intracellular iron ion homeostasis
Ad	0006955	biological_process	immune response
Ad	0008198	molecular_function	ferrous iron binding
Ad	0008199	molecular_function	ferric iron binding
Ad	0008285	biological_process	negative regulation of cell population proliferation
Ad	0016491	molecular_function	oxidoreductase activity
Ad	0031410	cellular_component	cytoplasmic vesicle
Ad	0042802	molecular_function	identical protein binding
Ad	0044754	cellular_component	autolysosome
Ad	0046872	molecular_function	metal ion binding
Ad	0048147	biological_process	negative regulation of fibroblast proliferation
Ad	0070062	cellular_component	extracellular exosome
Ad	0070288	cellular_component	ferritin complex
Ad	0110076	biological_process	negative regulation of ferroptosis
Ad	0140315	molecular_function	iron ion sequestering activity
Ad	1904724	cellular_component	tertiary granule lumen
Ad	1904813	cellular_component	ficolin-1-rich granule lumen
Ae	0004322	molecular_function	ferroxidase activity
Ae	0005506	molecular_function	iron ion binding
Ae	0005515	molecular_function	protein binding
Ae	0005576	cellular_component	extracellular region
Ae	0005634	cellular_component	nucleus
Ae	0005737	cellular_component	cytoplasm
Ae	0005764	cellular_component	lysosome
Ae	0005776	cellular_component	autophagosome
Ae	0005829	cellular_component	cytosol
Ae	0006826	biological_process	iron ion transport
Ae	0006879	biological_process	intracellular iron ion homeostasis
Ae	0006955	biological_process	immune response
Ae	0008198	molecular_function	ferrous iron binding
Ae	0008199	molecular_function	ferric iron binding
Ae	0008285	biological_process	negative regulation of cell population proliferation
Ae	0016491	molecular_function	oxidoreductase activity
Ae	0031410	cellular_component	cytoplasmic vesicle
Ae	0042802	molecular_function	identical protein binding
Ae	0044754	cellular_component	autolysosome
Ae	0046872	molecular_function	metal ion binding
Ae	0048147	biological_process	negative regulation of fibroblast proliferation
Ae	0070062	cellular_component	extracellular exosome
Ae	0070288	cellular_component	ferritin complex
Ae	0110076	biological_process	negative regulation of ferroptosis
Ae	0140315	molecular_function	iron ion sequestering activity
Ae	1904724	cellular_component	tertiary granule lumen
Ae	1904813	cellular_component	ficolin-1-rich granule lumen
Af	0004322	molecular_function	ferroxidase activity
Af	0005506	molecular_function	iron ion binding
Af	0005515	molecular_function	protein binding
Af	0005576	cellular_component	extracellular region
Af	0005634	cellular_component	nucleus
Af	0005737	cellular_component	cytoplasm
Af	0005764	cellular_component	lysosome
Af	0005776	cellular_component	autophagosome
Af	0005829	cellular_component	cytosol
Af	0006826	biological_process	iron ion transport
Af	0006879	biological_process	intracellular iron ion homeostasis
Af	0006955	biological_process	immune response
Af	0008198	molecular_function	ferrous iron binding
Af	0008199	molecular_function	ferric iron binding
Af	0008285	biological_process	negative regulation of cell population proliferation
Af	0016491	molecular_function	oxidoreductase activity
Af	0031410	cellular_component	cytoplasmic vesicle
Af	0042802	molecular_function	identical protein binding
Af	0044754	cellular_component	autolysosome
Af	0046872	molecular_function	metal ion binding
Af	0048147	biological_process	negative regulation of fibroblast proliferation
Af	0070062	cellular_component	extracellular exosome
Af	0070288	cellular_component	ferritin complex
Af	0110076	biological_process	negative regulation of ferroptosis
Af	0140315	molecular_function	iron ion sequestering activity
Af	1904724	cellular_component	tertiary granule lumen
Af	1904813	cellular_component	ficolin-1-rich granule lumen
Ag	0004322	molecular_function	ferroxidase activity
Ag	0005506	molecular_function	iron ion binding
Ag	0005515	molecular_function	protein binding
Ag	0005576	cellular_component	extracellular region
Ag	0005634	cellular_component	nucleus
Ag	0005737	cellular_component	cytoplasm
Ag	0005764	cellular_component	lysosome
Ag	0005776	cellular_component	autophagosome
Ag	0005829	cellular_component	cytosol
Ag	0006826	biological_process	iron ion transport
Ag	0006879	biological_process	intracellular iron ion homeostasis
Ag	0006955	biological_process	immune response
Ag	0008198	molecular_function	ferrous iron binding
Ag	0008199	molecular_function	ferric iron binding
Ag	0008285	biological_process	negative regulation of cell population proliferation
Ag	0016491	molecular_function	oxidoreductase activity
Ag	0031410	cellular_component	cytoplasmic vesicle
Ag	0042802	molecular_function	identical protein binding
Ag	0044754	cellular_component	autolysosome
Ag	0046872	molecular_function	metal ion binding
Ag	0048147	biological_process	negative regulation of fibroblast proliferation
Ag	0070062	cellular_component	extracellular exosome
Ag	0070288	cellular_component	ferritin complex
Ag	0110076	biological_process	negative regulation of ferroptosis
Ag	0140315	molecular_function	iron ion sequestering activity
Ag	1904724	cellular_component	tertiary granule lumen
Ag	1904813	cellular_component	ficolin-1-rich granule lumen
Ah	0004322	molecular_function	ferroxidase activity
Ah	0005506	molecular_function	iron ion binding
Ah	0005515	molecular_function	protein binding
Ah	0005576	cellular_component	extracellular region
Ah	0005634	cellular_component	nucleus
Ah	0005737	cellular_component	cytoplasm
Ah	0005764	cellular_component	lysosome
Ah	0005776	cellular_component	autophagosome
Ah	0005829	cellular_component	cytosol
Ah	0006826	biological_process	iron ion transport
Ah	0006879	biological_process	intracellular iron ion homeostasis
Ah	0006955	biological_process	immune response
Ah	0008198	molecular_function	ferrous iron binding
Ah	0008199	molecular_function	ferric iron binding
Ah	0008285	biological_process	negative regulation of cell population proliferation
Ah	0016491	molecular_function	oxidoreductase activity
Ah	0031410	cellular_component	cytoplasmic vesicle
Ah	0042802	molecular_function	identical protein binding
Ah	0044754	cellular_component	autolysosome
Ah	0046872	molecular_function	metal ion binding
Ah	0048147	biological_process	negative regulation of fibroblast proliferation
Ah	0070062	cellular_component	extracellular exosome
Ah	0070288	cellular_component	ferritin complex
Ah	0110076	biological_process	negative regulation of ferroptosis
Ah	0140315	molecular_function	iron ion sequestering activity
Ah	1904724	cellular_component	tertiary granule lumen
Ah	1904813	cellular_component	ficolin-1-rich granule lumen
Ai	0004322	molecular_function	ferroxidase activity
Ai	0005506	molecular_function	iron ion binding
Ai	0005515	molecular_function	protein binding
Ai	0005576	cellular_component	extracellular region
Ai	0005634	cellular_component	nucleus
Ai	0005737	cellular_component	cytoplasm
Ai	0005764	cellular_component	lysosome
Ai	0005776	cellular_component	autophagosome
Ai	0005829	cellular_component	cytosol
Ai	0006826	biological_process	iron ion transport
Ai	0006879	biological_process	intracellular iron ion homeostasis
Ai	0006955	biological_process	immune response
Ai	0008198	molecular_function	ferrous iron binding
Ai	0008199	molecular_function	ferric iron binding
Ai	0008285	biological_process	negative regulation of cell population proliferation
Ai	0016491	molecular_function	oxidoreductase activity
Ai	0031410	cellular_component	cytoplasmic vesicle
Ai	0042802	molecular_function	identical protein binding
Ai	0044754	cellular_component	autolysosome
Ai	0046872	molecular_function	metal ion binding
Ai	0048147	biological_process	negative regulation of fibroblast proliferation
Ai	0070062	cellular_component	extracellular exosome
Ai	0070288	cellular_component	ferritin complex
Ai	0110076	biological_process	negative regulation of ferroptosis
Ai	0140315	molecular_function	iron ion sequestering activity
Ai	1904724	cellular_component	tertiary granule lumen
Ai	1904813	cellular_component	ficolin-1-rich granule lumen
Aj	0004322	molecular_function	ferroxidase activity
Aj	0005506	molecular_function	iron ion binding
Aj	0005515	molecular_function	protein binding
Aj	0005576	cellular_component	extracellular region
Aj	0005634	cellular_component	nucleus
Aj	0005737	cellular_component	cytoplasm
Aj	0005764	cellular_component	lysosome
Aj	0005776	cellular_component	autophagosome
Aj	0005829	cellular_component	cytosol
Aj	0006826	biological_process	iron ion transport
Aj	0006879	biological_process	intracellular iron ion homeostasis
Aj	0006955	biological_process	immune response
Aj	0008198	molecular_function	ferrous iron binding
Aj	0008199	molecular_function	ferric iron binding
Aj	0008285	biological_process	negative regulation of cell population proliferation
Aj	0016491	molecular_function	oxidoreductase activity
Aj	0031410	cellular_component	cytoplasmic vesicle
Aj	0042802	molecular_function	identical protein binding
Aj	0044754	cellular_component	autolysosome
Aj	0046872	molecular_function	metal ion binding
Aj	0048147	biological_process	negative regulation of fibroblast proliferation
Aj	0070062	cellular_component	extracellular exosome
Aj	0070288	cellular_component	ferritin complex
Aj	0110076	biological_process	negative regulation of ferroptosis
Aj	0140315	molecular_function	iron ion sequestering activity
Aj	1904724	cellular_component	tertiary granule lumen
Aj	1904813	cellular_component	ficolin-1-rich granule lumen
Ak	0004322	molecular_function	ferroxidase activity
Ak	0005506	molecular_function	iron ion binding
Ak	0005515	molecular_function	protein binding
Ak	0005576	cellular_component	extracellular region
Ak	0005634	cellular_component	nucleus
Ak	0005737	cellular_component	cytoplasm
Ak	0005764	cellular_component	lysosome
Ak	0005776	cellular_component	autophagosome
Ak	0005829	cellular_component	cytosol
Ak	0006826	biological_process	iron ion transport
Ak	0006879	biological_process	intracellular iron ion homeostasis
Ak	0006955	biological_process	immune response
Ak	0008198	molecular_function	ferrous iron binding
Ak	0008199	molecular_function	ferric iron binding
Ak	0008285	biological_process	negative regulation of cell population proliferation
Ak	0016491	molecular_function	oxidoreductase activity
Ak	0031410	cellular_component	cytoplasmic vesicle
Ak	0042802	molecular_function	identical protein binding
Ak	0044754	cellular_component	autolysosome
Ak	0046872	molecular_function	metal ion binding
Ak	0048147	biological_process	negative regulation of fibroblast proliferation
Ak	0070062	cellular_component	extracellular exosome
Ak	0070288	cellular_component	ferritin complex
Ak	0110076	biological_process	negative regulation of ferroptosis
Ak	0140315	molecular_function	iron ion sequestering activity
Ak	1904724	cellular_component	tertiary granule lumen
Ak	1904813	cellular_component	ficolin-1-rich granule lumen
Al	0004322	molecular_function	ferroxidase activity
Al	0005506	molecular_function	iron ion binding
Al	0005515	molecular_function	protein binding
Al	0005576	cellular_component	extracellular region
Al	0005634	cellular_component	nucleus
Al	0005737	cellular_component	cytoplasm
Al	0005764	cellular_component	lysosome
Al	0005776	cellular_component	autophagosome
Al	0005829	cellular_component	cytosol
Al	0006826	biological_process	iron ion transport
Al	0006879	biological_process	intracellular iron ion homeostasis
Al	0006955	biological_process	immune response
Al	0008198	molecular_function	ferrous iron binding
Al	0008199	molecular_function	ferric iron binding
Al	0008285	biological_process	negative regulation of cell population proliferation
Al	0016491	molecular_function	oxidoreductase activity
Al	0031410	cellular_component	cytoplasmic vesicle
Al	0042802	molecular_function	identical protein binding
Al	0044754	cellular_component	autolysosome
Al	0046872	molecular_function	metal ion binding
Al	0048147	biological_process	negative regulation of fibroblast proliferation
Al	0070062	cellular_component	extracellular exosome
Al	0070288	cellular_component	ferritin complex
Al	0110076	biological_process	negative regulation of ferroptosis
Al	0140315	molecular_function	iron ion sequestering activity
Al	1904724	cellular_component	tertiary granule lumen
Al	1904813	cellular_component	ficolin-1-rich granule lumen
Am	0004322	molecular_function	ferroxidase activity
Am	0005506	molecular_function	iron ion binding
Am	0005515	molecular_function	protein binding
Am	0005576	cellular_component	extracellular region
Am	0005634	cellular_component	nucleus
Am	0005737	cellular_component	cytoplasm
Am	0005764	cellular_component	lysosome
Am	0005776	cellular_component	autophagosome
Am	0005829	cellular_component	cytosol
Am	0006826	biological_process	iron ion transport
Am	0006879	biological_process	intracellular iron ion homeostasis
Am	0006955	biological_process	immune response
Am	0008198	molecular_function	ferrous iron binding
Am	0008199	molecular_function	ferric iron binding
Am	0008285	biological_process	negative regulation of cell population proliferation
Am	0016491	molecular_function	oxidoreductase activity
Am	0031410	cellular_component	cytoplasmic vesicle
Am	0042802	molecular_function	identical protein binding
Am	0044754	cellular_component	autolysosome
Am	0046872	molecular_function	metal ion binding
Am	0048147	biological_process	negative regulation of fibroblast proliferation
Am	0070062	cellular_component	extracellular exosome
Am	0070288	cellular_component	ferritin complex
Am	0110076	biological_process	negative regulation of ferroptosis
Am	0140315	molecular_function	iron ion sequestering activity
Am	1904724	cellular_component	tertiary granule lumen
Am	1904813	cellular_component	ficolin-1-rich granule lumen
An	0004322	molecular_function	ferroxidase activity
An	0005506	molecular_function	iron ion binding
An	0005515	molecular_function	protein binding
An	0005576	cellular_component	extracellular region
An	0005634	cellular_component	nucleus
An	0005737	cellular_component	cytoplasm
An	0005764	cellular_component	lysosome
An	0005776	cellular_component	autophagosome
An	0005829	cellular_component	cytosol
An	0006826	biological_process	iron ion transport
An	0006879	biological_process	intracellular iron ion homeostasis
An	0006955	biological_process	immune response
An	0008198	molecular_function	ferrous iron binding
An	0008199	molecular_function	ferric iron binding
An	0008285	biological_process	negative regulation of cell population proliferation
An	0016491	molecular_function	oxidoreductase activity
An	0031410	cellular_component	cytoplasmic vesicle
An	0042802	molecular_function	identical protein binding
An	0044754	cellular_component	autolysosome
An	0046872	molecular_function	metal ion binding
An	0048147	biological_process	negative regulation of fibroblast proliferation
An	0070062	cellular_component	extracellular exosome
An	0070288	cellular_component	ferritin complex
An	0110076	biological_process	negative regulation of ferroptosis
An	0140315	molecular_function	iron ion sequestering activity
An	1904724	cellular_component	tertiary granule lumen
An	1904813	cellular_component	ficolin-1-rich granule lumen
Ao	0004322	molecular_function	ferroxidase activity
Ao	0005506	molecular_function	iron ion binding
Ao	0005515	molecular_function	protein binding
Ao	0005576	cellular_component	extracellular region
Ao	0005634	cellular_component	nucleus
Ao	0005737	cellular_component	cytoplasm
Ao	0005764	cellular_component	lysosome
Ao	0005776	cellular_component	autophagosome
Ao	0005829	cellular_component	cytosol
Ao	0006826	biological_process	iron ion transport
Ao	0006879	biological_process	intracellular iron ion homeostasis
Ao	0006955	biological_process	immune response
Ao	0008198	molecular_function	ferrous iron binding
Ao	0008199	molecular_function	ferric iron binding
Ao	0008285	biological_process	negative regulation of cell population proliferation
Ao	0016491	molecular_function	oxidoreductase activity
Ao	0031410	cellular_component	cytoplasmic vesicle
Ao	0042802	molecular_function	identical protein binding
Ao	0044754	cellular_component	autolysosome
Ao	0046872	molecular_function	metal ion binding
Ao	0048147	biological_process	negative regulation of fibroblast proliferation
Ao	0070062	cellular_component	extracellular exosome
Ao	0070288	cellular_component	ferritin complex
Ao	0110076	biological_process	negative regulation of ferroptosis
Ao	0140315	molecular_function	iron ion sequestering activity
Ao	1904724	cellular_component	tertiary granule lumen
Ao	1904813	cellular_component	ficolin-1-rich granule lumen
Ap	0004322	molecular_function	ferroxidase activity
Ap	0005506	molecular_function	iron ion binding
Ap	0005515	molecular_function	protein binding
Ap	0005576	cellular_component	extracellular region
Ap	0005634	cellular_component	nucleus
Ap	0005737	cellular_component	cytoplasm
Ap	0005764	cellular_component	lysosome
Ap	0005776	cellular_component	autophagosome
Ap	0005829	cellular_component	cytosol
Ap	0006826	biological_process	iron ion transport
Ap	0006879	biological_process	intracellular iron ion homeostasis
Ap	0006955	biological_process	immune response
Ap	0008198	molecular_function	ferrous iron binding
Ap	0008199	molecular_function	ferric iron binding
Ap	0008285	biological_process	negative regulation of cell population proliferation
Ap	0016491	molecular_function	oxidoreductase activity
Ap	0031410	cellular_component	cytoplasmic vesicle
Ap	0042802	molecular_function	identical protein binding
Ap	0044754	cellular_component	autolysosome
Ap	0046872	molecular_function	metal ion binding
Ap	0048147	biological_process	negative regulation of fibroblast proliferation
Ap	0070062	cellular_component	extracellular exosome
Ap	0070288	cellular_component	ferritin complex
Ap	0110076	biological_process	negative regulation of ferroptosis
Ap	0140315	molecular_function	iron ion sequestering activity
Ap	1904724	cellular_component	tertiary granule lumen
Ap	1904813	cellular_component	ficolin-1-rich granule lumen
Aq	0004998	molecular_function	transferrin receptor activity
Aq	0033572	biological_process	transferrin transport
Ar	0004322	molecular_function	ferroxidase activity
Ar	0005506	molecular_function	iron ion binding
Ar	0005515	molecular_function	protein binding
Ar	0005576	cellular_component	extracellular region
Ar	0005634	cellular_component	nucleus
Ar	0005737	cellular_component	cytoplasm
Ar	0005764	cellular_component	lysosome
Ar	0005776	cellular_component	autophagosome
Ar	0005829	cellular_component	cytosol
Ar	0006826	biological_process	iron ion transport
Ar	0006879	biological_process	intracellular iron ion homeostasis
Ar	0006955	biological_process	immune response
Ar	0008198	molecular_function	ferrous iron binding
Ar	0008199	molecular_function	ferric iron binding
Ar	0008285	biological_process	negative regulation of cell population proliferation
Ar	0016491	molecular_function	oxidoreductase activity
Ar	0031410	cellular_component	cytoplasmic vesicle
Ar	0042802	molecular_function	identical protein binding
Ar	0044754	cellular_component	autolysosome
Ar	0046872	molecular_function	metal ion binding
Ar	0048147	biological_process	negative regulation of fibroblast proliferation
Ar	0070062	cellular_component	extracellular exosome
Ar	0070288	cellular_component	ferritin complex
Ar	0110076	biological_process	negative regulation of ferroptosis
Ar	0140315	molecular_function	iron ion sequestering activity
Ar	1904724	cellular_component	tertiary granule lumen
Ar	1904813	cellular_component	ficolin-1-rich granule lumen
As	0004322	molecular_function	ferroxidase activity
As	0005506	molecular_function	iron ion binding
As	0005515	molecular_function	protein binding
As	0005576	cellular_component	extracellular region
As	0005634	cellular_component	nucleus
As	0005737	cellular_component	cytoplasm
As	0005764	cellular_component	lysosome
As	0005776	cellular_component	autophagosome
As	0005829	cellular_component	cytosol
As	0006826	biological_process	iron ion transport
As	0006879	biological_process	intracellular iron ion homeostasis
As	0006955	biological_process	immune response
As	0008198	molecular_function	ferrous iron binding
As	0008199	molecular_function	ferric iron binding
As	0008285	biological_process	negative regulation of cell population proliferation
As	0016491	molecular_function	oxidoreductase activity
As	0031410	cellular_component	cytoplasmic vesicle
As	0042802	molecular_function	identical protein binding
As	0044754	cellular_component	autolysosome
As	0046872	molecular_function	metal ion binding
As	0048147	biological_process	negative regulation of fibroblast proliferation
As	0070062	cellular_component	extracellular exosome
As	0070288	cellular_component	ferritin complex
As	0110076	biological_process	negative regulation of ferroptosis
As	0140315	molecular_function	iron ion sequestering activity
As	1904724	cellular_component	tertiary granule lumen
As	1904813	cellular_component	ficolin-1-rich granule lumen
At	0004322	molecular_function	ferroxidase activity
At	0005506	molecular_function	iron ion binding
At	0005515	molecular_function	protein binding
At	0005576	cellular_component	extracellular region
At	0005634	cellular_component	nucleus
At	0005737	cellular_component	cytoplasm
At	0005764	cellular_component	lysosome
At	0005776	cellular_component	autophagosome
At	0005829	cellular_component	cytosol
At	0006826	biological_process	iron ion transport
At	0006879	biological_process	intracellular iron ion homeostasis
At	0006955	biological_process	immune response
At	0008198	molecular_function	ferrous iron binding
At	0008199	molecular_function	ferric iron binding
At	0008285	biological_process	negative regulation of cell population proliferation
At	0016491	molecular_function	oxidoreductase activity
At	0031410	cellular_component	cytoplasmic vesicle
At	0042802	molecular_function	identical protein binding
At	0044754	cellular_component	autolysosome
At	0046872	molecular_function	metal ion binding
At	0048147	biological_process	negative regulation of fibroblast proliferation
At	0070062	cellular_component	extracellular exosome
At	0070288	cellular_component	ferritin complex
At	0110076	biological_process	negative regulation of ferroptosis
At	0140315	molecular_function	iron ion sequestering activity
At	1904724	cellular_component	tertiary granule lumen
At	1904813	cellular_component	ficolin-1-rich granule lumen
Au	0004322	molecular_function	ferroxidase activity
Au	0005506	molecular_function	iron ion binding
Au	0005515	molecular_function	protein binding
Au	0005576	cellular_component	extracellular region
Au	0005634	cellular_component	nucleus
Au	0005737	cellular_component	cytoplasm
Au	0005764	cellular_component	lysosome
Au	0005776	cellular_component	autophagosome
Au	0005829	cellular_component	cytosol
Au	0006826	biological_process	iron ion transport
Au	0006879	biological_process	intracellular iron ion homeostasis
Au	0006955	biological_process	immune response
Au	0008198	molecular_function	ferrous iron binding
Au	0008199	molecular_function	ferric iron binding
Au	0008285	biological_process	negative regulation of cell population proliferation
Au	0016491	molecular_function	oxidoreductase activity
Au	0031410	cellular_component	cytoplasmic vesicle
Au	0042802	molecular_function	identical protein binding
Au	0044754	cellular_component	autolysosome
Au	0046872	molecular_function	metal ion binding
Au	0048147	biological_process	negative regulation of fibroblast proliferation
Au	0070062	cellular_component	extracellular exosome
Au	0070288	cellular_component	ferritin complex
Au	0110076	biological_process	negative regulation of ferroptosis
Au	0140315	molecular_function	iron ion sequestering activity
Au	1904724	cellular_component	tertiary granule lumen
Au	1904813	cellular_component	ficolin-1-rich granule lumen
Av	0004322	molecular_function	ferroxidase activity
Av	0005506	molecular_function	iron ion binding
Av	0005515	molecular_function	protein binding
Av	0005576	cellular_component	extracellular region
Av	0005634	cellular_component	nucleus
Av	0005737	cellular_component	cytoplasm
Av	0005764	cellular_component	lysosome
Av	0005776	cellular_component	autophagosome
Av	0005829	cellular_component	cytosol
Av	0006826	biological_process	iron ion transport
Av	0006879	biological_process	intracellular iron ion homeostasis
Av	0006955	biological_process	immune response
Av	0008198	molecular_function	ferrous iron binding
Av	0008199	molecular_function	ferric iron binding
Av	0008285	biological_process	negative regulation of cell population proliferation
Av	0016491	molecular_function	oxidoreductase activity
Av	0031410	cellular_component	cytoplasmic vesicle
Av	0042802	molecular_function	identical protein binding
Av	0044754	cellular_component	autolysosome
Av	0046872	molecular_function	metal ion binding
Av	0048147	biological_process	negative regulation of fibroblast proliferation
Av	0070062	cellular_component	extracellular exosome
Av	0070288	cellular_component	ferritin complex
Av	0110076	biological_process	negative regulation of ferroptosis
Av	0140315	molecular_function	iron ion sequestering activity
Av	1904724	cellular_component	tertiary granule lumen
Av	1904813	cellular_component	ficolin-1-rich granule lumen
Aw	0004322	molecular_function	ferroxidase activity
Aw	0005506	molecular_function	iron ion binding
Aw	0005515	molecular_function	protein binding
Aw	0005576	cellular_component	extracellular region
Aw	0005634	cellular_component	nucleus
Aw	0005737	cellular_component	cytoplasm
Aw	0005764	cellular_component	lysosome
Aw	0005776	cellular_component	autophagosome
Aw	0005829	cellular_component	cytosol
Aw	0006826	biological_process	iron ion transport
Aw	0006879	biological_process	intracellular iron ion homeostasis
Aw	0006955	biological_process	immune response
Aw	0008198	molecular_function	ferrous iron binding
Aw	0008199	molecular_function	ferric iron binding
Aw	0008285	biological_process	negative regulation of cell population proliferation
Aw	0016491	molecular_function	oxidoreductase activity
Aw	0031410	cellular_component	cytoplasmic vesicle
Aw	0042802	molecular_function	identical protein binding
Aw	0044754	cellular_component	autolysosome
Aw	0046872	molecular_function	metal ion binding
Aw	0048147	biological_process	negative regulation of fibroblast proliferation
Aw	0070062	cellular_component	extracellular exosome
Aw	0070288	cellular_component	ferritin complex
Aw	0110076	biological_process	negative regulation of ferroptosis
Aw	0140315	molecular_function	iron ion sequestering activity
Aw	1904724	cellular_component	tertiary granule lumen
Aw	1904813	cellular_component	ficolin-1-rich granule lumen
Ax	0004322	molecular_function	ferroxidase activity
Ax	0005506	molecular_function	iron ion binding
Ax	0005515	molecular_function	protein binding
Ax	0005576	cellular_component	extracellular region
Ax	0005634	cellular_component	nucleus
Ax	0005737	cellular_component	cytoplasm
Ax	0005764	cellular_component	lysosome
Ax	0005776	cellular_component	autophagosome
Ax	0005829	cellular_component	cytosol
Ax	0006826	biological_process	iron ion transport
Ax	0006879	biological_process	intracellular iron ion homeostasis
Ax	0006955	biological_process	immune response
Ax	0008198	molecular_function	ferrous iron binding
Ax	0008199	molecular_function	ferric iron binding
Ax	0008285	biological_process	negative regulation of cell population proliferation
Ax	0016491	molecular_function	oxidoreductase activity
Ax	0031410	cellular_component	cytoplasmic vesicle
Ax	0042802	molecular_function	identical protein binding
Ax	0044754	cellular_component	autolysosome
Ax	0046872	molecular_function	metal ion binding
Ax	0048147	biological_process	negative regulation of fibroblast proliferation
Ax	0070062	cellular_component	extracellular exosome
Ax	0070288	cellular_component	ferritin complex
Ax	0110076	biological_process	negative regulation of ferroptosis
Ax	0140315	molecular_function	iron ion sequestering activity
Ax	1904724	cellular_component	tertiary granule lumen
Ax	1904813	cellular_component	ficolin-1-rich granule lumen
Ay	0004322	molecular_function	ferroxidase activity
Ay	0005506	molecular_function	iron ion binding
Ay	0005515	molecular_function	protein binding
Ay	0005576	cellular_component	extracellular region
Ay	0005634	cellular_component	nucleus
Ay	0005737	cellular_component	cytoplasm
Ay	0005764	cellular_component	lysosome
Ay	0005776	cellular_component	autophagosome
Ay	0005829	cellular_component	cytosol
Ay	0006826	biological_process	iron ion transport
Ay	0006879	biological_process	intracellular iron ion homeostasis
Ay	0006955	biological_process	immune response
Ay	0008198	molecular_function	ferrous iron binding
Ay	0008199	molecular_function	ferric iron binding
Ay	0008285	biological_process	negative regulation of cell population proliferation
Ay	0016491	molecular_function	oxidoreductase activity
Ay	0031410	cellular_component	cytoplasmic vesicle
Ay	0042802	molecular_function	identical protein binding
Ay	0044754	cellular_component	autolysosome
Ay	0046872	molecular_function	metal ion binding
Ay	0048147	biological_process	negative regulation of fibroblast proliferation
Ay	0070062	cellular_component	extracellular exosome
Ay	0070288	cellular_component	ferritin complex
Ay	0110076	biological_process	negative regulation of ferroptosis
Ay	0140315	molecular_function	iron ion sequestering activity
Ay	1904724	cellular_component	tertiary granule lumen
Ay	1904813	cellular_component	ficolin-1-rich granule lumen
Az	0004322	molecular_function	ferroxidase activity
Az	0005506	molecular_function	iron ion binding
Az	0005515	molecular_function	protein binding
Az	0005576	cellular_component	extracellular region
Az	0005634	cellular_component	nucleus
Az	0005737	cellular_component	cytoplasm
Az	0005764	cellular_component	lysosome
Az	0005776	cellular_component	autophagosome
Az	0005829	cellular_component	cytosol
Az	0006826	biological_process	iron ion transport
Az	0006879	biological_process	intracellular iron ion homeostasis
Az	0006955	biological_process	immune response
Az	0008198	molecular_function	ferrous iron binding
Az	0008199	molecular_function	ferric iron binding
Az	0008285	biological_process	negative regulation of cell population proliferation
Az	0016491	molecular_function	oxidoreductase activity
Az	0031410	cellular_component	cytoplasmic vesicle
Az	0042802	molecular_function	identical protein binding
Az	0044754	cellular_component	autolysosome
Az	0046872	molecular_function	metal ion binding
Az	0048147	biological_process	negative regulation of fibroblast proliferation
Az	0070062	cellular_component	extracellular exosome
Az	0070288	cellular_component	ferritin complex
Az	0110076	biological_process	negative regulation of ferroptosis
Az	0140315	molecular_function	iron ion sequestering activity
Az	1904724	cellular_component	tertiary granule lumen
Az	1904813	cellular_component	ficolin-1-rich granule lumen

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFIEthYLneqvkaIK

Chain	Residue	Details
Aa	ASP126-LYS146

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKLMklQNqRgGR

Chain	Residue	Details
Aa	GLU61-ARG79

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3427
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"1992356","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FHA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Site: {"description":"Essential for association with cargo receptor NCOA4","evidences":[{"source":"PubMed","id":"26436293","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	180
Details	Domain: {"description":"PA"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Motif: {"description":"Cell attachment site; required for binding to transferrin"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10531064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CX8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000173","evidences":[{"source":"PubMed","id":"10531064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7780197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CX8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---