6H5I

Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0004322	molecular_function	ferroxidase activity
Aa	0005506	molecular_function	iron ion binding
Aa	0005515	molecular_function	protein binding
Aa	0005576	cellular_component	extracellular region
Aa	0005634	cellular_component	nucleus
Aa	0005737	cellular_component	cytoplasm
Aa	0005764	cellular_component	lysosome
Aa	0005776	cellular_component	autophagosome
Aa	0005829	cellular_component	cytosol
Aa	0006826	biological_process	iron ion transport
Aa	0006879	biological_process	intracellular iron ion homeostasis
Aa	0006880	biological_process	intracellular sequestering of iron ion
Aa	0006955	biological_process	immune response
Aa	0008198	molecular_function	ferrous iron binding
Aa	0008199	molecular_function	ferric iron binding
Aa	0008285	biological_process	negative regulation of cell population proliferation
Aa	0016020	cellular_component	membrane
Aa	0016491	molecular_function	oxidoreductase activity
Aa	0031410	cellular_component	cytoplasmic vesicle
Aa	0042802	molecular_function	identical protein binding
Aa	0044754	cellular_component	autolysosome
Aa	0046872	molecular_function	metal ion binding
Aa	0048147	biological_process	negative regulation of fibroblast proliferation
Aa	0070062	cellular_component	extracellular exosome
Aa	0070288	cellular_component	ferritin complex
Aa	0110076	biological_process	negative regulation of ferroptosis
Aa	0140315	molecular_function	iron ion sequestering activity
Aa	1904724	cellular_component	tertiary granule lumen
Aa	1904813	cellular_component	ficolin-1-rich granule lumen
Ab	0004998	molecular_function	transferrin receptor activity
Ab	0033572	biological_process	transferrin transport
Ac	0004322	molecular_function	ferroxidase activity
Ac	0005506	molecular_function	iron ion binding
Ac	0005515	molecular_function	protein binding
Ac	0005576	cellular_component	extracellular region
Ac	0005634	cellular_component	nucleus
Ac	0005737	cellular_component	cytoplasm
Ac	0005764	cellular_component	lysosome
Ac	0005776	cellular_component	autophagosome
Ac	0005829	cellular_component	cytosol
Ac	0006826	biological_process	iron ion transport
Ac	0006879	biological_process	intracellular iron ion homeostasis
Ac	0006880	biological_process	intracellular sequestering of iron ion
Ac	0006955	biological_process	immune response
Ac	0008198	molecular_function	ferrous iron binding
Ac	0008199	molecular_function	ferric iron binding
Ac	0008285	biological_process	negative regulation of cell population proliferation
Ac	0016020	cellular_component	membrane
Ac	0016491	molecular_function	oxidoreductase activity
Ac	0031410	cellular_component	cytoplasmic vesicle
Ac	0042802	molecular_function	identical protein binding
Ac	0044754	cellular_component	autolysosome
Ac	0046872	molecular_function	metal ion binding
Ac	0048147	biological_process	negative regulation of fibroblast proliferation
Ac	0070062	cellular_component	extracellular exosome
Ac	0070288	cellular_component	ferritin complex
Ac	0110076	biological_process	negative regulation of ferroptosis
Ac	0140315	molecular_function	iron ion sequestering activity
Ac	1904724	cellular_component	tertiary granule lumen
Ac	1904813	cellular_component	ficolin-1-rich granule lumen
Ad	0004322	molecular_function	ferroxidase activity
Ad	0005506	molecular_function	iron ion binding
Ad	0005515	molecular_function	protein binding
Ad	0005576	cellular_component	extracellular region
Ad	0005634	cellular_component	nucleus
Ad	0005737	cellular_component	cytoplasm
Ad	0005764	cellular_component	lysosome
Ad	0005776	cellular_component	autophagosome
Ad	0005829	cellular_component	cytosol
Ad	0006826	biological_process	iron ion transport
Ad	0006879	biological_process	intracellular iron ion homeostasis
Ad	0006880	biological_process	intracellular sequestering of iron ion
Ad	0006955	biological_process	immune response
Ad	0008198	molecular_function	ferrous iron binding
Ad	0008199	molecular_function	ferric iron binding
Ad	0008285	biological_process	negative regulation of cell population proliferation
Ad	0016020	cellular_component	membrane
Ad	0016491	molecular_function	oxidoreductase activity
Ad	0031410	cellular_component	cytoplasmic vesicle
Ad	0042802	molecular_function	identical protein binding
Ad	0044754	cellular_component	autolysosome
Ad	0046872	molecular_function	metal ion binding
Ad	0048147	biological_process	negative regulation of fibroblast proliferation
Ad	0070062	cellular_component	extracellular exosome
Ad	0070288	cellular_component	ferritin complex
Ad	0110076	biological_process	negative regulation of ferroptosis
Ad	0140315	molecular_function	iron ion sequestering activity
Ad	1904724	cellular_component	tertiary granule lumen
Ad	1904813	cellular_component	ficolin-1-rich granule lumen
Ae	0004322	molecular_function	ferroxidase activity
Ae	0005506	molecular_function	iron ion binding
Ae	0005515	molecular_function	protein binding
Ae	0005576	cellular_component	extracellular region
Ae	0005634	cellular_component	nucleus
Ae	0005737	cellular_component	cytoplasm
Ae	0005764	cellular_component	lysosome
Ae	0005776	cellular_component	autophagosome
Ae	0005829	cellular_component	cytosol
Ae	0006826	biological_process	iron ion transport
Ae	0006879	biological_process	intracellular iron ion homeostasis
Ae	0006880	biological_process	intracellular sequestering of iron ion
Ae	0006955	biological_process	immune response
Ae	0008198	molecular_function	ferrous iron binding
Ae	0008199	molecular_function	ferric iron binding
Ae	0008285	biological_process	negative regulation of cell population proliferation
Ae	0016020	cellular_component	membrane
Ae	0016491	molecular_function	oxidoreductase activity
Ae	0031410	cellular_component	cytoplasmic vesicle
Ae	0042802	molecular_function	identical protein binding
Ae	0044754	cellular_component	autolysosome
Ae	0046872	molecular_function	metal ion binding
Ae	0048147	biological_process	negative regulation of fibroblast proliferation
Ae	0070062	cellular_component	extracellular exosome
Ae	0070288	cellular_component	ferritin complex
Ae	0110076	biological_process	negative regulation of ferroptosis
Ae	0140315	molecular_function	iron ion sequestering activity
Ae	1904724	cellular_component	tertiary granule lumen
Ae	1904813	cellular_component	ficolin-1-rich granule lumen
Af	0004322	molecular_function	ferroxidase activity
Af	0005506	molecular_function	iron ion binding
Af	0005515	molecular_function	protein binding
Af	0005576	cellular_component	extracellular region
Af	0005634	cellular_component	nucleus
Af	0005737	cellular_component	cytoplasm
Af	0005764	cellular_component	lysosome
Af	0005776	cellular_component	autophagosome
Af	0005829	cellular_component	cytosol
Af	0006826	biological_process	iron ion transport
Af	0006879	biological_process	intracellular iron ion homeostasis
Af	0006880	biological_process	intracellular sequestering of iron ion
Af	0006955	biological_process	immune response
Af	0008198	molecular_function	ferrous iron binding
Af	0008199	molecular_function	ferric iron binding
Af	0008285	biological_process	negative regulation of cell population proliferation
Af	0016020	cellular_component	membrane
Af	0016491	molecular_function	oxidoreductase activity
Af	0031410	cellular_component	cytoplasmic vesicle
Af	0042802	molecular_function	identical protein binding
Af	0044754	cellular_component	autolysosome
Af	0046872	molecular_function	metal ion binding
Af	0048147	biological_process	negative regulation of fibroblast proliferation
Af	0070062	cellular_component	extracellular exosome
Af	0070288	cellular_component	ferritin complex
Af	0110076	biological_process	negative regulation of ferroptosis
Af	0140315	molecular_function	iron ion sequestering activity
Af	1904724	cellular_component	tertiary granule lumen
Af	1904813	cellular_component	ficolin-1-rich granule lumen
Ag	0004322	molecular_function	ferroxidase activity
Ag	0005506	molecular_function	iron ion binding
Ag	0005515	molecular_function	protein binding
Ag	0005576	cellular_component	extracellular region
Ag	0005634	cellular_component	nucleus
Ag	0005737	cellular_component	cytoplasm
Ag	0005764	cellular_component	lysosome
Ag	0005776	cellular_component	autophagosome
Ag	0005829	cellular_component	cytosol
Ag	0006826	biological_process	iron ion transport
Ag	0006879	biological_process	intracellular iron ion homeostasis
Ag	0006880	biological_process	intracellular sequestering of iron ion
Ag	0006955	biological_process	immune response
Ag	0008198	molecular_function	ferrous iron binding
Ag	0008199	molecular_function	ferric iron binding
Ag	0008285	biological_process	negative regulation of cell population proliferation
Ag	0016020	cellular_component	membrane
Ag	0016491	molecular_function	oxidoreductase activity
Ag	0031410	cellular_component	cytoplasmic vesicle
Ag	0042802	molecular_function	identical protein binding
Ag	0044754	cellular_component	autolysosome
Ag	0046872	molecular_function	metal ion binding
Ag	0048147	biological_process	negative regulation of fibroblast proliferation
Ag	0070062	cellular_component	extracellular exosome
Ag	0070288	cellular_component	ferritin complex
Ag	0110076	biological_process	negative regulation of ferroptosis
Ag	0140315	molecular_function	iron ion sequestering activity
Ag	1904724	cellular_component	tertiary granule lumen
Ag	1904813	cellular_component	ficolin-1-rich granule lumen
Ah	0004322	molecular_function	ferroxidase activity
Ah	0005506	molecular_function	iron ion binding
Ah	0005515	molecular_function	protein binding
Ah	0005576	cellular_component	extracellular region
Ah	0005634	cellular_component	nucleus
Ah	0005737	cellular_component	cytoplasm
Ah	0005764	cellular_component	lysosome
Ah	0005776	cellular_component	autophagosome
Ah	0005829	cellular_component	cytosol
Ah	0006826	biological_process	iron ion transport
Ah	0006879	biological_process	intracellular iron ion homeostasis
Ah	0006880	biological_process	intracellular sequestering of iron ion
Ah	0006955	biological_process	immune response
Ah	0008198	molecular_function	ferrous iron binding
Ah	0008199	molecular_function	ferric iron binding
Ah	0008285	biological_process	negative regulation of cell population proliferation
Ah	0016020	cellular_component	membrane
Ah	0016491	molecular_function	oxidoreductase activity
Ah	0031410	cellular_component	cytoplasmic vesicle
Ah	0042802	molecular_function	identical protein binding
Ah	0044754	cellular_component	autolysosome
Ah	0046872	molecular_function	metal ion binding
Ah	0048147	biological_process	negative regulation of fibroblast proliferation
Ah	0070062	cellular_component	extracellular exosome
Ah	0070288	cellular_component	ferritin complex
Ah	0110076	biological_process	negative regulation of ferroptosis
Ah	0140315	molecular_function	iron ion sequestering activity
Ah	1904724	cellular_component	tertiary granule lumen
Ah	1904813	cellular_component	ficolin-1-rich granule lumen
Ai	0004322	molecular_function	ferroxidase activity
Ai	0005506	molecular_function	iron ion binding
Ai	0005515	molecular_function	protein binding
Ai	0005576	cellular_component	extracellular region
Ai	0005634	cellular_component	nucleus
Ai	0005737	cellular_component	cytoplasm
Ai	0005764	cellular_component	lysosome
Ai	0005776	cellular_component	autophagosome
Ai	0005829	cellular_component	cytosol
Ai	0006826	biological_process	iron ion transport
Ai	0006879	biological_process	intracellular iron ion homeostasis
Ai	0006880	biological_process	intracellular sequestering of iron ion
Ai	0006955	biological_process	immune response
Ai	0008198	molecular_function	ferrous iron binding
Ai	0008199	molecular_function	ferric iron binding
Ai	0008285	biological_process	negative regulation of cell population proliferation
Ai	0016020	cellular_component	membrane
Ai	0016491	molecular_function	oxidoreductase activity
Ai	0031410	cellular_component	cytoplasmic vesicle
Ai	0042802	molecular_function	identical protein binding
Ai	0044754	cellular_component	autolysosome
Ai	0046872	molecular_function	metal ion binding
Ai	0048147	biological_process	negative regulation of fibroblast proliferation
Ai	0070062	cellular_component	extracellular exosome
Ai	0070288	cellular_component	ferritin complex
Ai	0110076	biological_process	negative regulation of ferroptosis
Ai	0140315	molecular_function	iron ion sequestering activity
Ai	1904724	cellular_component	tertiary granule lumen
Ai	1904813	cellular_component	ficolin-1-rich granule lumen
Aj	0004322	molecular_function	ferroxidase activity
Aj	0005506	molecular_function	iron ion binding
Aj	0005515	molecular_function	protein binding
Aj	0005576	cellular_component	extracellular region
Aj	0005634	cellular_component	nucleus
Aj	0005737	cellular_component	cytoplasm
Aj	0005764	cellular_component	lysosome
Aj	0005776	cellular_component	autophagosome
Aj	0005829	cellular_component	cytosol
Aj	0006826	biological_process	iron ion transport
Aj	0006879	biological_process	intracellular iron ion homeostasis
Aj	0006880	biological_process	intracellular sequestering of iron ion
Aj	0006955	biological_process	immune response
Aj	0008198	molecular_function	ferrous iron binding
Aj	0008199	molecular_function	ferric iron binding
Aj	0008285	biological_process	negative regulation of cell population proliferation
Aj	0016020	cellular_component	membrane
Aj	0016491	molecular_function	oxidoreductase activity
Aj	0031410	cellular_component	cytoplasmic vesicle
Aj	0042802	molecular_function	identical protein binding
Aj	0044754	cellular_component	autolysosome
Aj	0046872	molecular_function	metal ion binding
Aj	0048147	biological_process	negative regulation of fibroblast proliferation
Aj	0070062	cellular_component	extracellular exosome
Aj	0070288	cellular_component	ferritin complex
Aj	0110076	biological_process	negative regulation of ferroptosis
Aj	0140315	molecular_function	iron ion sequestering activity
Aj	1904724	cellular_component	tertiary granule lumen
Aj	1904813	cellular_component	ficolin-1-rich granule lumen
Ak	0004322	molecular_function	ferroxidase activity
Ak	0005506	molecular_function	iron ion binding
Ak	0005515	molecular_function	protein binding
Ak	0005576	cellular_component	extracellular region
Ak	0005634	cellular_component	nucleus
Ak	0005737	cellular_component	cytoplasm
Ak	0005764	cellular_component	lysosome
Ak	0005776	cellular_component	autophagosome
Ak	0005829	cellular_component	cytosol
Ak	0006826	biological_process	iron ion transport
Ak	0006879	biological_process	intracellular iron ion homeostasis
Ak	0006880	biological_process	intracellular sequestering of iron ion
Ak	0006955	biological_process	immune response
Ak	0008198	molecular_function	ferrous iron binding
Ak	0008199	molecular_function	ferric iron binding
Ak	0008285	biological_process	negative regulation of cell population proliferation
Ak	0016020	cellular_component	membrane
Ak	0016491	molecular_function	oxidoreductase activity
Ak	0031410	cellular_component	cytoplasmic vesicle
Ak	0042802	molecular_function	identical protein binding
Ak	0044754	cellular_component	autolysosome
Ak	0046872	molecular_function	metal ion binding
Ak	0048147	biological_process	negative regulation of fibroblast proliferation
Ak	0070062	cellular_component	extracellular exosome
Ak	0070288	cellular_component	ferritin complex
Ak	0110076	biological_process	negative regulation of ferroptosis
Ak	0140315	molecular_function	iron ion sequestering activity
Ak	1904724	cellular_component	tertiary granule lumen
Ak	1904813	cellular_component	ficolin-1-rich granule lumen
Al	0004322	molecular_function	ferroxidase activity
Al	0005506	molecular_function	iron ion binding
Al	0005515	molecular_function	protein binding
Al	0005576	cellular_component	extracellular region
Al	0005634	cellular_component	nucleus
Al	0005737	cellular_component	cytoplasm
Al	0005764	cellular_component	lysosome
Al	0005776	cellular_component	autophagosome
Al	0005829	cellular_component	cytosol
Al	0006826	biological_process	iron ion transport
Al	0006879	biological_process	intracellular iron ion homeostasis
Al	0006880	biological_process	intracellular sequestering of iron ion
Al	0006955	biological_process	immune response
Al	0008198	molecular_function	ferrous iron binding
Al	0008199	molecular_function	ferric iron binding
Al	0008285	biological_process	negative regulation of cell population proliferation
Al	0016020	cellular_component	membrane
Al	0016491	molecular_function	oxidoreductase activity
Al	0031410	cellular_component	cytoplasmic vesicle
Al	0042802	molecular_function	identical protein binding
Al	0044754	cellular_component	autolysosome
Al	0046872	molecular_function	metal ion binding
Al	0048147	biological_process	negative regulation of fibroblast proliferation
Al	0070062	cellular_component	extracellular exosome
Al	0070288	cellular_component	ferritin complex
Al	0110076	biological_process	negative regulation of ferroptosis
Al	0140315	molecular_function	iron ion sequestering activity
Al	1904724	cellular_component	tertiary granule lumen
Al	1904813	cellular_component	ficolin-1-rich granule lumen
Am	0004322	molecular_function	ferroxidase activity
Am	0005506	molecular_function	iron ion binding
Am	0005515	molecular_function	protein binding
Am	0005576	cellular_component	extracellular region
Am	0005634	cellular_component	nucleus
Am	0005737	cellular_component	cytoplasm
Am	0005764	cellular_component	lysosome
Am	0005776	cellular_component	autophagosome
Am	0005829	cellular_component	cytosol
Am	0006826	biological_process	iron ion transport
Am	0006879	biological_process	intracellular iron ion homeostasis
Am	0006880	biological_process	intracellular sequestering of iron ion
Am	0006955	biological_process	immune response
Am	0008198	molecular_function	ferrous iron binding
Am	0008199	molecular_function	ferric iron binding
Am	0008285	biological_process	negative regulation of cell population proliferation
Am	0016020	cellular_component	membrane
Am	0016491	molecular_function	oxidoreductase activity
Am	0031410	cellular_component	cytoplasmic vesicle
Am	0042802	molecular_function	identical protein binding
Am	0044754	cellular_component	autolysosome
Am	0046872	molecular_function	metal ion binding
Am	0048147	biological_process	negative regulation of fibroblast proliferation
Am	0070062	cellular_component	extracellular exosome
Am	0070288	cellular_component	ferritin complex
Am	0110076	biological_process	negative regulation of ferroptosis
Am	0140315	molecular_function	iron ion sequestering activity
Am	1904724	cellular_component	tertiary granule lumen
Am	1904813	cellular_component	ficolin-1-rich granule lumen
An	0004322	molecular_function	ferroxidase activity
An	0005506	molecular_function	iron ion binding
An	0005515	molecular_function	protein binding
An	0005576	cellular_component	extracellular region
An	0005634	cellular_component	nucleus
An	0005737	cellular_component	cytoplasm
An	0005764	cellular_component	lysosome
An	0005776	cellular_component	autophagosome
An	0005829	cellular_component	cytosol
An	0006826	biological_process	iron ion transport
An	0006879	biological_process	intracellular iron ion homeostasis
An	0006880	biological_process	intracellular sequestering of iron ion
An	0006955	biological_process	immune response
An	0008198	molecular_function	ferrous iron binding
An	0008199	molecular_function	ferric iron binding
An	0008285	biological_process	negative regulation of cell population proliferation
An	0016020	cellular_component	membrane
An	0016491	molecular_function	oxidoreductase activity
An	0031410	cellular_component	cytoplasmic vesicle
An	0042802	molecular_function	identical protein binding
An	0044754	cellular_component	autolysosome
An	0046872	molecular_function	metal ion binding
An	0048147	biological_process	negative regulation of fibroblast proliferation
An	0070062	cellular_component	extracellular exosome
An	0070288	cellular_component	ferritin complex
An	0110076	biological_process	negative regulation of ferroptosis
An	0140315	molecular_function	iron ion sequestering activity
An	1904724	cellular_component	tertiary granule lumen
An	1904813	cellular_component	ficolin-1-rich granule lumen
Ao	0004322	molecular_function	ferroxidase activity
Ao	0005506	molecular_function	iron ion binding
Ao	0005515	molecular_function	protein binding
Ao	0005576	cellular_component	extracellular region
Ao	0005634	cellular_component	nucleus
Ao	0005737	cellular_component	cytoplasm
Ao	0005764	cellular_component	lysosome
Ao	0005776	cellular_component	autophagosome
Ao	0005829	cellular_component	cytosol
Ao	0006826	biological_process	iron ion transport
Ao	0006879	biological_process	intracellular iron ion homeostasis
Ao	0006880	biological_process	intracellular sequestering of iron ion
Ao	0006955	biological_process	immune response
Ao	0008198	molecular_function	ferrous iron binding
Ao	0008199	molecular_function	ferric iron binding
Ao	0008285	biological_process	negative regulation of cell population proliferation
Ao	0016020	cellular_component	membrane
Ao	0016491	molecular_function	oxidoreductase activity
Ao	0031410	cellular_component	cytoplasmic vesicle
Ao	0042802	molecular_function	identical protein binding
Ao	0044754	cellular_component	autolysosome
Ao	0046872	molecular_function	metal ion binding
Ao	0048147	biological_process	negative regulation of fibroblast proliferation
Ao	0070062	cellular_component	extracellular exosome
Ao	0070288	cellular_component	ferritin complex
Ao	0110076	biological_process	negative regulation of ferroptosis
Ao	0140315	molecular_function	iron ion sequestering activity
Ao	1904724	cellular_component	tertiary granule lumen
Ao	1904813	cellular_component	ficolin-1-rich granule lumen
Ap	0004322	molecular_function	ferroxidase activity
Ap	0005506	molecular_function	iron ion binding
Ap	0005515	molecular_function	protein binding
Ap	0005576	cellular_component	extracellular region
Ap	0005634	cellular_component	nucleus
Ap	0005737	cellular_component	cytoplasm
Ap	0005764	cellular_component	lysosome
Ap	0005776	cellular_component	autophagosome
Ap	0005829	cellular_component	cytosol
Ap	0006826	biological_process	iron ion transport
Ap	0006879	biological_process	intracellular iron ion homeostasis
Ap	0006880	biological_process	intracellular sequestering of iron ion
Ap	0006955	biological_process	immune response
Ap	0008198	molecular_function	ferrous iron binding
Ap	0008199	molecular_function	ferric iron binding
Ap	0008285	biological_process	negative regulation of cell population proliferation
Ap	0016020	cellular_component	membrane
Ap	0016491	molecular_function	oxidoreductase activity
Ap	0031410	cellular_component	cytoplasmic vesicle
Ap	0042802	molecular_function	identical protein binding
Ap	0044754	cellular_component	autolysosome
Ap	0046872	molecular_function	metal ion binding
Ap	0048147	biological_process	negative regulation of fibroblast proliferation
Ap	0070062	cellular_component	extracellular exosome
Ap	0070288	cellular_component	ferritin complex
Ap	0110076	biological_process	negative regulation of ferroptosis
Ap	0140315	molecular_function	iron ion sequestering activity
Ap	1904724	cellular_component	tertiary granule lumen
Ap	1904813	cellular_component	ficolin-1-rich granule lumen
Aq	0004998	molecular_function	transferrin receptor activity
Aq	0033572	biological_process	transferrin transport
Ar	0004322	molecular_function	ferroxidase activity
Ar	0005506	molecular_function	iron ion binding
Ar	0005515	molecular_function	protein binding
Ar	0005576	cellular_component	extracellular region
Ar	0005634	cellular_component	nucleus
Ar	0005737	cellular_component	cytoplasm
Ar	0005764	cellular_component	lysosome
Ar	0005776	cellular_component	autophagosome
Ar	0005829	cellular_component	cytosol
Ar	0006826	biological_process	iron ion transport
Ar	0006879	biological_process	intracellular iron ion homeostasis
Ar	0006880	biological_process	intracellular sequestering of iron ion
Ar	0006955	biological_process	immune response
Ar	0008198	molecular_function	ferrous iron binding
Ar	0008199	molecular_function	ferric iron binding
Ar	0008285	biological_process	negative regulation of cell population proliferation
Ar	0016020	cellular_component	membrane
Ar	0016491	molecular_function	oxidoreductase activity
Ar	0031410	cellular_component	cytoplasmic vesicle
Ar	0042802	molecular_function	identical protein binding
Ar	0044754	cellular_component	autolysosome
Ar	0046872	molecular_function	metal ion binding
Ar	0048147	biological_process	negative regulation of fibroblast proliferation
Ar	0070062	cellular_component	extracellular exosome
Ar	0070288	cellular_component	ferritin complex
Ar	0110076	biological_process	negative regulation of ferroptosis
Ar	0140315	molecular_function	iron ion sequestering activity
Ar	1904724	cellular_component	tertiary granule lumen
Ar	1904813	cellular_component	ficolin-1-rich granule lumen
As	0004322	molecular_function	ferroxidase activity
As	0005506	molecular_function	iron ion binding
As	0005515	molecular_function	protein binding
As	0005576	cellular_component	extracellular region
As	0005634	cellular_component	nucleus
As	0005737	cellular_component	cytoplasm
As	0005764	cellular_component	lysosome
As	0005776	cellular_component	autophagosome
As	0005829	cellular_component	cytosol
As	0006826	biological_process	iron ion transport
As	0006879	biological_process	intracellular iron ion homeostasis
As	0006880	biological_process	intracellular sequestering of iron ion
As	0006955	biological_process	immune response
As	0008198	molecular_function	ferrous iron binding
As	0008199	molecular_function	ferric iron binding
As	0008285	biological_process	negative regulation of cell population proliferation
As	0016020	cellular_component	membrane
As	0016491	molecular_function	oxidoreductase activity
As	0031410	cellular_component	cytoplasmic vesicle
As	0042802	molecular_function	identical protein binding
As	0044754	cellular_component	autolysosome
As	0046872	molecular_function	metal ion binding
As	0048147	biological_process	negative regulation of fibroblast proliferation
As	0070062	cellular_component	extracellular exosome
As	0070288	cellular_component	ferritin complex
As	0110076	biological_process	negative regulation of ferroptosis
As	0140315	molecular_function	iron ion sequestering activity
As	1904724	cellular_component	tertiary granule lumen
As	1904813	cellular_component	ficolin-1-rich granule lumen
At	0004322	molecular_function	ferroxidase activity
At	0005506	molecular_function	iron ion binding
At	0005515	molecular_function	protein binding
At	0005576	cellular_component	extracellular region
At	0005634	cellular_component	nucleus
At	0005737	cellular_component	cytoplasm
At	0005764	cellular_component	lysosome
At	0005776	cellular_component	autophagosome
At	0005829	cellular_component	cytosol
At	0006826	biological_process	iron ion transport
At	0006879	biological_process	intracellular iron ion homeostasis
At	0006880	biological_process	intracellular sequestering of iron ion
At	0006955	biological_process	immune response
At	0008198	molecular_function	ferrous iron binding
At	0008199	molecular_function	ferric iron binding
At	0008285	biological_process	negative regulation of cell population proliferation
At	0016020	cellular_component	membrane
At	0016491	molecular_function	oxidoreductase activity
At	0031410	cellular_component	cytoplasmic vesicle
At	0042802	molecular_function	identical protein binding
At	0044754	cellular_component	autolysosome
At	0046872	molecular_function	metal ion binding
At	0048147	biological_process	negative regulation of fibroblast proliferation
At	0070062	cellular_component	extracellular exosome
At	0070288	cellular_component	ferritin complex
At	0110076	biological_process	negative regulation of ferroptosis
At	0140315	molecular_function	iron ion sequestering activity
At	1904724	cellular_component	tertiary granule lumen
At	1904813	cellular_component	ficolin-1-rich granule lumen
Au	0004322	molecular_function	ferroxidase activity
Au	0005506	molecular_function	iron ion binding
Au	0005515	molecular_function	protein binding
Au	0005576	cellular_component	extracellular region
Au	0005634	cellular_component	nucleus
Au	0005737	cellular_component	cytoplasm
Au	0005764	cellular_component	lysosome
Au	0005776	cellular_component	autophagosome
Au	0005829	cellular_component	cytosol
Au	0006826	biological_process	iron ion transport
Au	0006879	biological_process	intracellular iron ion homeostasis
Au	0006880	biological_process	intracellular sequestering of iron ion
Au	0006955	biological_process	immune response
Au	0008198	molecular_function	ferrous iron binding
Au	0008199	molecular_function	ferric iron binding
Au	0008285	biological_process	negative regulation of cell population proliferation
Au	0016020	cellular_component	membrane
Au	0016491	molecular_function	oxidoreductase activity
Au	0031410	cellular_component	cytoplasmic vesicle
Au	0042802	molecular_function	identical protein binding
Au	0044754	cellular_component	autolysosome
Au	0046872	molecular_function	metal ion binding
Au	0048147	biological_process	negative regulation of fibroblast proliferation
Au	0070062	cellular_component	extracellular exosome
Au	0070288	cellular_component	ferritin complex
Au	0110076	biological_process	negative regulation of ferroptosis
Au	0140315	molecular_function	iron ion sequestering activity
Au	1904724	cellular_component	tertiary granule lumen
Au	1904813	cellular_component	ficolin-1-rich granule lumen
Av	0004322	molecular_function	ferroxidase activity
Av	0005506	molecular_function	iron ion binding
Av	0005515	molecular_function	protein binding
Av	0005576	cellular_component	extracellular region
Av	0005634	cellular_component	nucleus
Av	0005737	cellular_component	cytoplasm
Av	0005764	cellular_component	lysosome
Av	0005776	cellular_component	autophagosome
Av	0005829	cellular_component	cytosol
Av	0006826	biological_process	iron ion transport
Av	0006879	biological_process	intracellular iron ion homeostasis
Av	0006880	biological_process	intracellular sequestering of iron ion
Av	0006955	biological_process	immune response
Av	0008198	molecular_function	ferrous iron binding
Av	0008199	molecular_function	ferric iron binding
Av	0008285	biological_process	negative regulation of cell population proliferation
Av	0016020	cellular_component	membrane
Av	0016491	molecular_function	oxidoreductase activity
Av	0031410	cellular_component	cytoplasmic vesicle
Av	0042802	molecular_function	identical protein binding
Av	0044754	cellular_component	autolysosome
Av	0046872	molecular_function	metal ion binding
Av	0048147	biological_process	negative regulation of fibroblast proliferation
Av	0070062	cellular_component	extracellular exosome
Av	0070288	cellular_component	ferritin complex
Av	0110076	biological_process	negative regulation of ferroptosis
Av	0140315	molecular_function	iron ion sequestering activity
Av	1904724	cellular_component	tertiary granule lumen
Av	1904813	cellular_component	ficolin-1-rich granule lumen
Aw	0004322	molecular_function	ferroxidase activity
Aw	0005506	molecular_function	iron ion binding
Aw	0005515	molecular_function	protein binding
Aw	0005576	cellular_component	extracellular region
Aw	0005634	cellular_component	nucleus
Aw	0005737	cellular_component	cytoplasm
Aw	0005764	cellular_component	lysosome
Aw	0005776	cellular_component	autophagosome
Aw	0005829	cellular_component	cytosol
Aw	0006826	biological_process	iron ion transport
Aw	0006879	biological_process	intracellular iron ion homeostasis
Aw	0006880	biological_process	intracellular sequestering of iron ion
Aw	0006955	biological_process	immune response
Aw	0008198	molecular_function	ferrous iron binding
Aw	0008199	molecular_function	ferric iron binding
Aw	0008285	biological_process	negative regulation of cell population proliferation
Aw	0016020	cellular_component	membrane
Aw	0016491	molecular_function	oxidoreductase activity
Aw	0031410	cellular_component	cytoplasmic vesicle
Aw	0042802	molecular_function	identical protein binding
Aw	0044754	cellular_component	autolysosome
Aw	0046872	molecular_function	metal ion binding
Aw	0048147	biological_process	negative regulation of fibroblast proliferation
Aw	0070062	cellular_component	extracellular exosome
Aw	0070288	cellular_component	ferritin complex
Aw	0110076	biological_process	negative regulation of ferroptosis
Aw	0140315	molecular_function	iron ion sequestering activity
Aw	1904724	cellular_component	tertiary granule lumen
Aw	1904813	cellular_component	ficolin-1-rich granule lumen
Ax	0004322	molecular_function	ferroxidase activity
Ax	0005506	molecular_function	iron ion binding
Ax	0005515	molecular_function	protein binding
Ax	0005576	cellular_component	extracellular region
Ax	0005634	cellular_component	nucleus
Ax	0005737	cellular_component	cytoplasm
Ax	0005764	cellular_component	lysosome
Ax	0005776	cellular_component	autophagosome
Ax	0005829	cellular_component	cytosol
Ax	0006826	biological_process	iron ion transport
Ax	0006879	biological_process	intracellular iron ion homeostasis
Ax	0006880	biological_process	intracellular sequestering of iron ion
Ax	0006955	biological_process	immune response
Ax	0008198	molecular_function	ferrous iron binding
Ax	0008199	molecular_function	ferric iron binding
Ax	0008285	biological_process	negative regulation of cell population proliferation
Ax	0016020	cellular_component	membrane
Ax	0016491	molecular_function	oxidoreductase activity
Ax	0031410	cellular_component	cytoplasmic vesicle
Ax	0042802	molecular_function	identical protein binding
Ax	0044754	cellular_component	autolysosome
Ax	0046872	molecular_function	metal ion binding
Ax	0048147	biological_process	negative regulation of fibroblast proliferation
Ax	0070062	cellular_component	extracellular exosome
Ax	0070288	cellular_component	ferritin complex
Ax	0110076	biological_process	negative regulation of ferroptosis
Ax	0140315	molecular_function	iron ion sequestering activity
Ax	1904724	cellular_component	tertiary granule lumen
Ax	1904813	cellular_component	ficolin-1-rich granule lumen
Ay	0004322	molecular_function	ferroxidase activity
Ay	0005506	molecular_function	iron ion binding
Ay	0005515	molecular_function	protein binding
Ay	0005576	cellular_component	extracellular region
Ay	0005634	cellular_component	nucleus
Ay	0005737	cellular_component	cytoplasm
Ay	0005764	cellular_component	lysosome
Ay	0005776	cellular_component	autophagosome
Ay	0005829	cellular_component	cytosol
Ay	0006826	biological_process	iron ion transport
Ay	0006879	biological_process	intracellular iron ion homeostasis
Ay	0006880	biological_process	intracellular sequestering of iron ion
Ay	0006955	biological_process	immune response
Ay	0008198	molecular_function	ferrous iron binding
Ay	0008199	molecular_function	ferric iron binding
Ay	0008285	biological_process	negative regulation of cell population proliferation
Ay	0016020	cellular_component	membrane
Ay	0016491	molecular_function	oxidoreductase activity
Ay	0031410	cellular_component	cytoplasmic vesicle
Ay	0042802	molecular_function	identical protein binding
Ay	0044754	cellular_component	autolysosome
Ay	0046872	molecular_function	metal ion binding
Ay	0048147	biological_process	negative regulation of fibroblast proliferation
Ay	0070062	cellular_component	extracellular exosome
Ay	0070288	cellular_component	ferritin complex
Ay	0110076	biological_process	negative regulation of ferroptosis
Ay	0140315	molecular_function	iron ion sequestering activity
Ay	1904724	cellular_component	tertiary granule lumen
Ay	1904813	cellular_component	ficolin-1-rich granule lumen
Az	0004322	molecular_function	ferroxidase activity
Az	0005506	molecular_function	iron ion binding
Az	0005515	molecular_function	protein binding
Az	0005576	cellular_component	extracellular region
Az	0005634	cellular_component	nucleus
Az	0005737	cellular_component	cytoplasm
Az	0005764	cellular_component	lysosome
Az	0005776	cellular_component	autophagosome
Az	0005829	cellular_component	cytosol
Az	0006826	biological_process	iron ion transport
Az	0006879	biological_process	intracellular iron ion homeostasis
Az	0006880	biological_process	intracellular sequestering of iron ion
Az	0006955	biological_process	immune response
Az	0008198	molecular_function	ferrous iron binding
Az	0008199	molecular_function	ferric iron binding
Az	0008285	biological_process	negative regulation of cell population proliferation
Az	0016020	cellular_component	membrane
Az	0016491	molecular_function	oxidoreductase activity
Az	0031410	cellular_component	cytoplasmic vesicle
Az	0042802	molecular_function	identical protein binding
Az	0044754	cellular_component	autolysosome
Az	0046872	molecular_function	metal ion binding
Az	0048147	biological_process	negative regulation of fibroblast proliferation
Az	0070062	cellular_component	extracellular exosome
Az	0070288	cellular_component	ferritin complex
Az	0110076	biological_process	negative regulation of ferroptosis
Az	0140315	molecular_function	iron ion sequestering activity
Az	1904724	cellular_component	tertiary granule lumen
Az	1904813	cellular_component	ficolin-1-rich granule lumen

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFIEthYLneqvkaIK

Chain	Residue	Details
Aa	ASP126-LYS146

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKLMklQNqRgGR

Chain	Residue	Details
Aa	GLU61-ARG79

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10531064, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973, ECO:0007744|PDB:1CX8

Chain	Residue	Details
Ab	ASN251
Af	HIS65
Ag	GLU27
Ag	HIS65
Ah	GLU27
Ah	HIS65
Ai	GLU27
Ai	HIS65
Aj	GLU27
Aj	HIS65
Ak	GLU27
Aq	ASN251
Ak	HIS65
Al	GLU27
Al	HIS65
Am	GLU27
Am	HIS65
An	GLU27
An	HIS65
Ao	GLU27
Ao	HIS65
Ap	GLU27
Ac	GLU27
Ap	HIS65
Ar	GLU27
Ar	HIS65
As	GLU27
As	HIS65
At	GLU27
At	HIS65
Au	GLU27
Au	HIS65
Av	GLU27
Ac	HIS65
Av	HIS65
Aw	GLU27
Aw	HIS65
Ax	GLU27
Ax	HIS65
Ay	GLU27
Ay	HIS65
Az	GLU27
Az	HIS65
Ad	GLU27
Ad	HIS65
Ae	GLU27
Ae	HIS65
Af	GLU27

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10531064, ECO:0007744|PDB:1CX8

Chain	Residue	Details
Ab	ASN317
Ae	GLU62
Ae	GLU107
Ae	GLN141
Af	GLU62
Af	GLU107
Af	GLN141
Ag	GLU62
Ag	GLU107
Ag	GLN141
Ah	GLU62
Aq	ASN317
Ah	GLU107
Ah	GLN141
Ai	GLU62
Ai	GLU107
Ai	GLN141
Aj	GLU62
Aj	GLU107
Aj	GLN141
Ak	GLU62
Ak	GLU107
Aa	GLN141
Ak	GLN141
Al	GLU62
Al	GLU107
Al	GLN141
Am	GLU62
Am	GLU107
Am	GLN141
An	GLU62
An	GLU107
An	GLN141
Ac	GLU62
Ao	GLU62
Ao	GLU107
Ao	GLN141
Ap	GLU62
Ap	GLU107
Ap	GLN141
Ar	GLU62
Ar	GLU107
Ar	GLN141
As	GLU62
Ac	GLU107
As	GLU107
As	GLN141
At	GLU62
At	GLU107
At	GLN141
Au	GLU62
Au	GLU107
Au	GLN141
Av	GLU62
Av	GLU107
Ac	GLN141
Av	GLN141
Aw	GLU62
Aw	GLU107
Aw	GLN141
Ax	GLU62
Ax	GLU107
Ax	GLN141
Ay	GLU62
Ay	GLU107
Ay	GLN141
Ad	GLU62
Az	GLU62
Az	GLU107
Az	GLN141
Ad	GLU107
Ad	GLN141

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10531064, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7780197, ECO:0007744|PDB:1CX8

Chain	Residue	Details
Ab	ASN727
Ak	ARG22
Al	ARG22
Am	ARG22
An	ARG22
Ao	ARG22
Ap	ARG22
Ar	ARG22
As	ARG22
At	ARG22
Au	ARG22
Aq	ASN727
Av	ARG22
Aw	ARG22
Ax	ARG22
Ay	ARG22
Az	ARG22
Ad	ARG22
Ae	ARG22
Af	ARG22
Ag	ARG22
Ah	ARG22
Ai	ARG22
Aj	ARG22

---