6H47
Human KRAS in complex with darpin K19
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | ALA11 |
| A | HOH344 |
| A | HOH363 |
| A | GLY13 |
| A | VAL14 |
| A | GLY15 |
| A | LYS16 |
| A | SER17 |
| A | HOH316 |
| A | HOH317 |
| A | HOH322 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | GLY47 |
| B | LEU49 |
| B | GLU50 |
| B | HOH305 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| B | ARG20 |
| B | ARG58 |
| B | LYS133 |
| B | PHE134 |
| B | HOH337 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | GLY80 |
| B | HIS81 |
| B | LEU82 |
| B | GLU83 |
| B | HOH326 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22431598","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22566140","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34380736","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"35522713","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine; in GTPase KRas; alternate","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Kolch W."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylthreonine; in GTPase KRas, N-terminally processed","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Kolch W."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"22711838","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
