6H3A

Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
B	0043130	molecular_function	ubiquitin binding
D	0043130	molecular_function	ubiquitin binding
F	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1001

Chain	Residue
A	CYS65
A	CYS68
A	CYS88
A	CYS91

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1002

Chain	Residue
A	CYS83
A	HIS85
A	CYS117
A	CYS120

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 1003

Chain	Residue
A	HIS212
A	CYS229
A	CYS232
A	CYS209

---

site_id	AC4
Number of Residues	5
Details	binding site for residue ZN A 1004

Chain	Residue
A	CYS221
A	SER223
A	CYS224
A	HIS237
A	HIS240

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN F 501

Chain	Residue
F	CYS209
F	HIS212
F	CYS229
F	CYS232

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN F 502

Chain	Residue
F	CYS221
F	CYS224
F	HIS237
F	HIS240

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN F 503

Chain	Residue
F	CYS65
F	CYS68
F	CYS88
F	CYS91

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN F 504

Chain	Residue
F	CYS83
F	HIS85
F	CYS117
F	VAL119
F	CYS120

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	112
Details	ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175

Chain	Residue	Details
A	CYS65-LYS121
F	CYS65-LYS121
B	SER124
B	SER127

---

site_id	SWS_FT_FI2
Number of Residues	94
Details	ZN_FING: B box-type 1; atypical => ECO:0000255|PROSITE-ProRule:PRU00024

Chain	Residue	Details
A	ASP148-THR195
F	ASP148-THR195

---

site_id	SWS_FT_FI3
Number of Residues	82
Details	ZN_FING: B box-type 2 => ECO:0000255|PROSITE-ProRule:PRU00024

Chain	Residue	Details
A	GLU204-LEU245
F	GLU204-LEU245

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00024

Chain	Residue	Details
F	CYS153
F	CYS156
F	CYS177
F	HIS181
F	CYS209
F	HIS212
F	CYS232
F	HIS237
A	CYS153
A	CYS156
A	CYS177
A	HIS181
A	CYS209
A	HIS212
A	CYS232
A	HIS237

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER138
A	SER417
F	SER138
F	SER417

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q62318

Chain	Residue	Details
A	LYS266
F	LYS266

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
F	LYS304
F	LYS377
A	LYS377
A	LYS304

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS340
F	LYS340

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS407
F	LYS127
F	LYS272
F	LYS407
A	LYS272
A	LYS127

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733

Chain	Residue	Details
F	LYS199
F	LYS254
F	LYS261
F	LYS319
F	LYS434
A	LYS319
A	LYS434
D	SER302
A	LYS199
A	LYS254
A	LYS261

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS304
B	LYS335
F	LYS304

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447

Chain	Residue	Details
A	LYS366
F	LYS366

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS377
F	LYS377

---