Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004089 | molecular_function | carbonate dehydratase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006730 | biological_process | one-carbon metabolic process |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016829 | molecular_function | lyase activity |
A | 0032230 | biological_process | positive regulation of synaptic transmission, GABAergic |
A | 0032849 | biological_process | positive regulation of cellular pH reduction |
A | 0046872 | molecular_function | metal ion binding |
A | 0051453 | biological_process | regulation of intracellular pH |
A | 0070050 | biological_process | neuron cellular homeostasis |
A | 2001225 | biological_process | regulation of chloride transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 301 |
Chain | Residue |
A | HIS94 |
A | HIS96 |
A | HIS119 |
A | FKK302 |
site_id | AC2 |
Number of Residues | 17 |
Details | binding site for residue FKK A 302 |
Chain | Residue |
A | VAL121 |
A | PHE131 |
A | ARG159 |
A | LEU198 |
A | THR199 |
A | THR200 |
A | PRO201 |
A | PRO202 |
A | ZN301 |
A | GOL303 |
A | HOH423 |
A | HOH522 |
A | TYR20 |
A | GLN92 |
A | HIS94 |
A | HIS96 |
A | HIS119 |
site_id | AC3 |
Number of Residues | 10 |
Details | binding site for residue GOL A 303 |
Chain | Residue |
A | ASN62 |
A | HIS64 |
A | SER65 |
A | GLN67 |
A | GLN92 |
A | HIS94 |
A | THR200 |
A | FKK302 |
A | HOH432 |
A | HOH479 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue GOL A 304 |
Chain | Residue |
A | LYS18 |
A | LEU19 |
A | CYS54 |
A | MET55 |
A | HOH426 |
A | HOH460 |
Functional Information from PROSITE/UniProt
site_id | PS00162 |
Number of Residues | 17 |
Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVdgksFpsELHLV |
Chain | Residue | Details |
A | SER105-VAL121 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS64 | |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|Ref.13 |
Chain | Residue | Details |
A | HIS94 | |
A | HIS96 | |
A | HIS119 | |
Chain | Residue | Details |
A | THR199 | |