6GY5
Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 701 |
| Chain | Residue |
| A | GLU344 |
| A | TRP345 |
| A | HOH944 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 702 |
| Chain | Residue |
| U | ALA1341 |
| U | TYR1343 |
| A | PHE562 |
| A | TYR567 |
| A | LEU592 |
| A | HOH946 |
| A | HOH973 |
| U | VAL1340 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 703 |
| Chain | Residue |
| A | PHE414 |
| A | ARG432 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 704 |
| Chain | Residue |
| A | GLY412 |
| A | GLY413 |
| A | PHE414 |
| A | ASP434 |
| A | LYS436 |
| A | EDO708 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 705 |
| Chain | Residue |
| A | LYS388 |
| A | THR389 |
| A | ASN390 |
| A | LEU474 |
| A | ASN475 |
| A | ARG496 |
| A | HOH871 |
| A | HOH1076 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 706 |
| Chain | Residue |
| A | SER381 |
| A | VAL382 |
| A | SER394 |
| A | VAL396 |
| A | ALA397 |
| A | PRO398 |
| A | EDO707 |
| A | HOH847 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 707 |
| Chain | Residue |
| A | SER394 |
| A | ASP395 |
| A | VAL396 |
| A | ALA397 |
| A | ASN438 |
| A | GLU484 |
| A | ARG486 |
| A | EDO706 |
| A | HOH917 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 708 |
| Chain | Residue |
| A | ASN428 |
| A | ASP434 |
| A | LYS436 |
| A | GLU437 |
| A | EDO704 |
| A | HOH816 |
| A | HOH825 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 709 |
| Chain | Residue |
| A | THR541 |
| A | TRP581 |
| A | LEU583 |
| A | HOH801 |
| A | HOH808 |
| A | HOH845 |
| A | HOH994 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 710 |
| Chain | Residue |
| A | GLY546 |
| A | GLY548 |
| A | VAL559 |
| A | ARG591 |
| A | GLY593 |
| A | GLY594 |
| A | GLY595 |
| A | VAL596 |
| A | HOH931 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 711 |
| Chain | Residue |
| A | SER333 |
| A | SER334 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 712 |
| Chain | Residue |
| A | VAL362 |
| A | GLY597 |
| A | VAL598 |
| A | HOH1097 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 713 |
| Chain | Residue |
| A | ASN481 |
| A | HIS488 |
| A | HOH820 |
| A | HOH1028 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 714 |
| Chain | Residue |
| A | GLU525 |
| A | TRP534 |
| A | SER535 |
| A | PRO536 |
| A | HOH1067 |
| A | HOH1164 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 715 |
| Chain | Residue |
| A | VAL348 |
| A | ALA349 |
| A | ASN390 |
| A | HOH984 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 716 |
| Chain | Residue |
| A | ARG496 |
| A | HOH814 |
| A | HOH991 |
| A | HOH1143 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 717 |
| Chain | Residue |
| A | THR566 |
| A | TYR567 |
| A | HOH953 |
| A | HOH1074 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 718 |
| Chain | Residue |
| U | LEU1339 |
| A | SER405 |
| A | GLN421 |
| U | PRO1337 |
| U | ASP1338 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 719 |
| Chain | Residue |
| A | ARG449 |
| A | HOH851 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 720 |
| Chain | Residue |
| A | SER377 |
| A | TYR378 |
| A | HOH893 |
| A | HOH1008 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 721 |
| Chain | Residue |
| A | LYS353 |
| A | ARG354 |
| A | HOH1005 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 722 |
| Chain | Residue |
| A | SER381 |
| A | HOH1006 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 723 |
| Chain | Residue |
| A | ARG590 |
| A | HOH1116 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 724 |
| Chain | Residue |
| A | SER468 |
| A | SER472 |
| A | PRO473 |
| A | LYS498 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 6"} |
| Chain | Residue | Details |
