6GXJ

X-ray structure of DiRu-1-encapsulated Apoferritin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005776	cellular_component	autophagosome
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0044754	cellular_component	autolysosome
A	0046872	molecular_function	metal ion binding
A	0070288	cellular_component	ferritin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CD A 201

Chain	Residue
A	GLU130
A	GLU130
A	GLU130
A	HOH318
A	HOH318
A	HOH318

---

site_id	AC2
Number of Residues	9
Details	binding site for residue CD A 202

Chain	Residue
A	HOH315
A	HOH315
A	HOH315
A	HOH362
A	HOH362
A	HOH362
A	ASP127
A	ASP127
A	ASP127

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CD A 203

Chain	Residue
A	GLU11
A	CL211
A	HOH363

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CD A 204

Chain	Residue
A	GLU56
A	GLU60
A	HOH302

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CD A 205

Chain	Residue
A	ASP80
A	ASP80
A	CL210
A	CL210

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CD A 206

Chain	Residue
A	HIS132
A	ASP135
A	HOH350
A	HOH377
A	HOH441

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CD A 207

Chain	Residue
A	GLU53
A	GLU56
A	HOH348

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CD A 208

Chain	Residue
A	CYS48
A	HIS49
A	ARG52
A	HOH471

---

site_id	AC9
Number of Residues	3
Details	binding site for residue CD A 209

Chain	Residue
A	SER118
A	CYS126
A	HOH452

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CL A 210

Chain	Residue
A	ASP80
A	LYS83
A	CD205
A	CD205
A	HOH447

---

site_id	AD2
Number of Residues	3
Details	binding site for residue CL A 211

Chain	Residue
A	SER9
A	THR10
A	CD203

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CD A 212

Chain	Residue
A	GLU45
A	HOH304
A	HOH383
A	HOH412
A	HOH413
A	HOH427

---

site_id	AD4
Number of Residues	5
Details	binding site for residue SO4 A 213

Chain	Residue
A	GLN6
A	ASN7
A	HOH307
A	HOH309
A	HOH322

---

site_id	AD5
Number of Residues	4
Details	binding site for residue GOL A 214

Chain	Residue
A	GLN3
A	LYS104
A	HOH386
A	HOH439

---

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL A 215

Chain	Residue
A	GLY90
A	ARG153
A	GLU163
A	HOH367

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshFLdeevklIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLkmQNqRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"Catalytic site for iron oxidation"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"7026284","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---