6GWD
Tubulin:iiH5 alphaRep complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005200 | molecular_function | structural constituent of cytoskeleton |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005874 | cellular_component | microtubule |
| A | 0007017 | biological_process | microtubule-based process |
| B | 0000226 | biological_process | microtubule cytoskeleton organization |
| B | 0000278 | biological_process | mitotic cell cycle |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005200 | molecular_function | structural constituent of cytoskeleton |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005874 | cellular_component | microtubule |
| B | 0007017 | biological_process | microtubule-based process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005200 | molecular_function | structural constituent of cytoskeleton |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005874 | cellular_component | microtubule |
| C | 0007017 | biological_process | microtubule-based process |
| D | 0000226 | biological_process | microtubule cytoskeleton organization |
| D | 0000278 | biological_process | mitotic cell cycle |
| D | 0003924 | molecular_function | GTPase activity |
| D | 0005200 | molecular_function | structural constituent of cytoskeleton |
| D | 0005525 | molecular_function | GTP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005856 | cellular_component | cytoskeleton |
| D | 0005874 | cellular_component | microtubule |
| D | 0007017 | biological_process | microtubule-based process |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0005200 | molecular_function | structural constituent of cytoskeleton |
| E | 0005525 | molecular_function | GTP binding |
| E | 0005874 | cellular_component | microtubule |
| E | 0007017 | biological_process | microtubule-based process |
| F | 0000226 | biological_process | microtubule cytoskeleton organization |
| F | 0000278 | biological_process | mitotic cell cycle |
| F | 0003924 | molecular_function | GTPase activity |
| F | 0005200 | molecular_function | structural constituent of cytoskeleton |
| F | 0005525 | molecular_function | GTP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005856 | cellular_component | cytoskeleton |
| F | 0005874 | cellular_component | microtubule |
| F | 0007017 | biological_process | microtubule-based process |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue GTP A 600 |
| Chain | Residue |
| A | GLY10 |
| A | ASN101 |
| A | SER140 |
| A | GLY143 |
| A | GLY144 |
| A | THR145 |
| A | GLY146 |
| A | ILE171 |
| A | VAL177 |
| A | THR179 |
| A | GLU183 |
| A | GLN11 |
| A | ASN206 |
| A | TYR224 |
| A | LEU227 |
| A | ASN228 |
| A | ILE231 |
| A | MG601 |
| B | LYS254 |
| A | ALA12 |
| A | GLN15 |
| A | ILE16 |
| A | GLU71 |
| A | ASP98 |
| A | ALA99 |
| A | ALA100 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | GLU71 |
| A | GTP600 |
| B | LYS254 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue GDP B 600 |
| Chain | Residue |
| B | GLY10 |
| B | GLN11 |
| B | CYS12 |
| B | GLN15 |
| B | SER140 |
| B | GLY143 |
| B | GLY144 |
| B | THR145 |
| B | GLY146 |
| B | PRO173 |
| B | VAL177 |
| B | SER178 |
| B | GLU183 |
| B | ASN206 |
| B | TYR224 |
| B | ASN228 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | binding site for residue GTP C 600 |
| Chain | Residue |
| C | GLY10 |
| C | GLN11 |
| C | ALA12 |
| C | GLN15 |
| C | ASP69 |
| C | ASP98 |
| C | ALA99 |
| C | ALA100 |
| C | ASN101 |
| C | SER140 |
| C | GLY143 |
| C | GLY144 |
| C | THR145 |
| C | GLY146 |
| C | VAL177 |
| C | GLU183 |
| C | ASN206 |
| C | TYR224 |
| C | ASN228 |
| C | ILE231 |
| C | MG601 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MG C 601 |
| Chain | Residue |
| C | GTP600 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue GDP D 600 |
| Chain | Residue |
| D | GLY10 |
| D | GLN11 |
| D | CYS12 |
| D | GLN15 |
| D | SER140 |
| D | GLY143 |
| D | GLY144 |
| D | THR145 |
| D | GLY146 |
| D | PRO173 |
| D | VAL177 |
| D | GLU183 |
| D | ASN206 |
| D | TYR224 |
| D | ASN228 |
| site_id | AC7 |
| Number of Residues | 24 |
| Details | binding site for residue GTP E 600 |
| Chain | Residue |
| E | GLU183 |
| E | ASN206 |
| E | TYR224 |
| E | ASN228 |
| E | ILE231 |
| E | MG601 |
| F | LYS254 |
| E | GLY10 |
| E | GLN11 |
| E | ALA12 |
| E | GLN15 |
| E | GLU71 |
| E | ASP98 |
| E | ALA99 |
| E | ALA100 |
| E | ASN101 |
| E | SER140 |
| E | GLY143 |
| E | GLY144 |
| E | THR145 |
| E | GLY146 |
| E | ILE171 |
| E | VAL177 |
| E | THR179 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue MG E 601 |
| Chain | Residue |
| E | GLU71 |
| E | GTP600 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue GDP F 600 |
| Chain | Residue |
| F | GLY10 |
| F | GLN11 |
| F | CYS12 |
| F | GLN15 |
| F | SER140 |
| F | GLY143 |
| F | GLY144 |
| F | THR145 |
| F | GLY146 |
| F | PRO173 |
| F | VAL177 |
| F | SER178 |
| F | GLU183 |
| F | ASN206 |
| F | TYR224 |
| F | ASN228 |
Functional Information from PROSITE/UniProt
