6GSP

RIBONUCLEASE T1/3'-GMP, 15 WEEKS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001411	cellular_component	hyphal tip
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0008150	biological_process	biological_process
A	0016787	molecular_function	hydrolase activity
A	0016829	molecular_function	lyase activity
A	0030428	cellular_component	cell septum
A	0046589	molecular_function	ribonuclease T1 activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA A 107

Chain	Residue
A	ASP15
A	HOH130

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site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 3GP A 105

Chain	Residue
A	TYR38
A	HIS40
A	LYS41
A	TYR42
A	ASN43
A	ASN44
A	TYR45
A	GLU46
A	GLU58
A	ARG77
A	HIS92
A	ASN98
A	PHE100
A	HOH118

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site_id	BI1
Number of Residues	5
Details	SITE.

Chain	Residue
A	GLU46
A	TYR42
A	ASN43
A	ASN44
A	TYR45

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site_id	CAL
Number of Residues	1
Details	SITE.

Chain	Residue
A	ASP15

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site_id	CAT
Number of Residues	5
Details	ACTIVE SITE.

Chain	Residue
A	TYR38
A	HIS40
A	GLU58
A	ARG77
A	HIS92

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:2844811

Chain	Residue	Details
A	TYR45

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000269|PubMed:2844811

Chain	Residue	Details
A	SER63

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site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: Proton donor

Chain	Residue	Details
A	GLY97

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 414

Chain	Residue	Details
A	ASN43	electrostatic stabiliser
A	TYR45	proton shuttle (general acid/base)
A	SER63	proton shuttle (general acid/base)
A	GLU82	electrostatic stabiliser
A	GLY97	proton shuttle (general acid/base)

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