6GKR

Crystal structure of branched-chain amino acid aminotransferase from Thermobaculum terrenum in PLP-form (holo-form)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid transaminase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0019752	biological_process	carboxylic acid metabolic process
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
A	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
A	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid transaminase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0019752	biological_process	carboxylic acid metabolic process
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
B	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
B	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid transaminase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0019752	biological_process	carboxylic acid metabolic process
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0052654	molecular_function	L-leucine-2-oxoglutarate transaminase activity
C	0052655	molecular_function	L-valine-2-oxoglutarate transaminase activity
C	0052656	molecular_function	L-isoleucine-2-oxoglutarate transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue PLP A 401

Chain	Residue
A	ARG64
A	ILE222
A	THR223
A	GLY259
A	THR260
A	CL403
A	HOH555
A	ARG150
A	LYS161
A	TYR166
A	GLU195
A	GLY198
A	SER199
A	LEU219
A	SER221

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site_id	AC2
Number of Residues	3
Details	binding site for residue ACT A 402

Chain	Residue
A	ASN152
B	ASN152
B	VAL155

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site_id	AC3
Number of Residues	3
Details	binding site for residue CL A 403

Chain	Residue
A	TYR101
A	HIS261
A	PLP401

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site_id	AC4
Number of Residues	3
Details	binding site for residue CL B 402

Chain	Residue
B	TYR101
B	HIS261
B	PLP401

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site_id	AC5
Number of Residues	21
Details	binding site for Di-peptide PLP B 401 and LYS B 161

Chain	Residue
B	VAL38
B	PHE39
B	ARG64
B	SER68
B	ARG150
B	ARG159
B	ILE160
B	ALA162
B	TYR166
B	GLU195
B	GLY198
B	SER199
B	CYS200
B	LEU219
B	SER221
B	ILE222
B	THR223
B	GLY259
B	THR260
B	CL402
B	HOH551

---

site_id	AC6
Number of Residues	19
Details	binding site for Di-peptide PLP C 401 and LYS C 161

Chain	Residue
C	VAL38
C	PHE39
C	ARG64
C	SER68
C	ARG150
C	ARG159
C	ILE160
C	ALA162
C	TYR166
C	GLU195
C	GLY198
C	SER199
C	LEU219
C	SER221
C	ILE222
C	THR223
C	GLY259
C	THR260
C	HOH542

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