6GGU

Crystal structure of native FE-hydrogenase from Methanothermobacter marburgensis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006730	biological_process	one-carbon metabolic process
A	0015948	biological_process	methanogenesis
A	0016491	molecular_function	oxidoreductase activity
A	0019386	biological_process	methanogenesis, from carbon dioxide
A	0047068	molecular_function	N5,N10-methenyltetrahydromethanopterin hydrogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue MES A 401

Chain	Residue
A	PHE230
A	ASN239
A	ALA240
A	TYR241
A	ARG242
A	ASP312
A	LYS344
A	HOH508
A	HOH521

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 402

Chain	Residue
A	GLN285
A	LYS289
A	GLU300

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 403

Chain	Residue
A	LYS181
A	LYS186
A	LYS289

---

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 404

Chain	Residue
A	PRO175
A	LYS186
A	HIS187

---

site_id	AC5
Number of Residues	27
Details	binding site for residue FE9 A 405

Chain	Residue
A	LEU6
A	GLY7
A	GLY9
A	CYS10
A	THR13
A	ALA62
A	ASP63
A	PRO64
A	PRO110
A	PRO111
A	ASP131
A	TRP144
A	PHE145
A	PRO146
A	ILE154
A	ALA171
A	CYS172
A	THR173
A	ASP189
A	HIS203
A	PRO204
A	GLY205
A	ALA206
A	VAL207
A	PRO208
A	HOH502
A	HOH535

---

site_id	AC6
Number of Residues	4
Details	binding site for residue GOL A 406

Chain	Residue
A	GLU340
A	HOH531
A	HOH532
A	HOH536

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL A 407

Chain	Residue
A	SER17
A	LEU190
A	VAL191
A	LYS193
A	GOL408
A	HOH515

---

site_id	AC8
Number of Residues	5
Details	binding site for residue GOL A 408

Chain	Residue
A	ILE19
A	SER322
A	PHE325
A	GOL407
A	HOH505

---

site_id	AC9
Number of Residues	3
Details	binding site for residue GOL A 409

Chain	Residue
A	ALA77
A	TYR78
A	GLU79

---

site_id	AD1
Number of Residues	1
Details	binding site for residue GOL A 410

Chain	Residue
A	GLY326

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