6GFZ
pVHL:EloB:EloC in complex with modified VH032 containing (3S,4S)-3-fluoro-4-hydroxyproline (ligand 14b)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006368 | biological_process | transcription elongation by RNA polymerase II |
A | 0030891 | cellular_component | VCB complex |
A | 0070449 | cellular_component | elongin complex |
B | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
D | 0006368 | biological_process | transcription elongation by RNA polymerase II |
D | 0030891 | cellular_component | VCB complex |
D | 0070449 | cellular_component | elongin complex |
E | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
G | 0006368 | biological_process | transcription elongation by RNA polymerase II |
G | 0030891 | cellular_component | VCB complex |
G | 0070449 | cellular_component | elongin complex |
H | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
J | 0006368 | biological_process | transcription elongation by RNA polymerase II |
J | 0030891 | cellular_component | VCB complex |
J | 0070449 | cellular_component | elongin complex |
K | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | binding site for residue EXE C 301 |
Chain | Residue |
C | TRP88 |
C | TRP117 |
C | HOH425 |
C | HOH433 |
C | HOH437 |
L | ARG182 |
C | PHE91 |
C | TYR98 |
C | PRO99 |
C | ILE109 |
C | HIS110 |
C | SER111 |
C | TYR112 |
C | HIS115 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue EXE F 301 |
Chain | Residue |
F | TRP88 |
F | PHE91 |
F | TYR98 |
F | PRO99 |
F | ILE109 |
F | HIS110 |
F | SER111 |
F | TYR112 |
F | HIS115 |
F | TRP117 |
F | HOH404 |
F | HOH434 |
F | HOH435 |
I | ARG182 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue EXE I 301 |
Chain | Residue |
I | TRP88 |
I | PHE91 |
I | TYR98 |
I | PRO99 |
I | ARG107 |
I | ILE109 |
I | HIS110 |
I | SER111 |
I | TYR112 |
I | HIS115 |
I | TRP117 |
I | HOH427 |
I | HOH437 |
site_id | AC4 |
Number of Residues | 14 |
Details | binding site for residue EXE L 301 |
Chain | Residue |
C | ARG182 |
L | TRP88 |
L | PHE91 |
L | TYR98 |
L | PRO99 |
L | ARG107 |
L | ILE109 |
L | HIS110 |
L | SER111 |
L | TYR112 |
L | HIS115 |
L | TRP117 |
L | HOH408 |
L | HOH426 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378 |
Chain | Residue | Details |
A | MET1 | |
D | MET1 | |
G | MET1 | |
J | MET1 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P62869 |
Chain | Residue | Details |
A | THR84 | |
D | THR84 | |
G | THR84 | |
J | THR84 |