6GFQ
cyanobacterial GAPDH with NAD and CP12 bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0043891 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity |
| A | 0047100 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0043891 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity |
| B | 0047100 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0080153 | biological_process | negative regulation of reductive pentose-phosphate cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue NAD A 1001 |
| Chain | Residue |
| A | GLY8 |
| A | ALA99 |
| A | THR100 |
| A | GLY101 |
| A | PHE103 |
| A | THR123 |
| A | ALA124 |
| A | CYS154 |
| A | ASN317 |
| A | TYR321 |
| A | HOH1119 |
| A | PHE9 |
| A | HOH1133 |
| A | HOH1153 |
| A | HOH1160 |
| A | HOH1163 |
| A | HOH1168 |
| A | HOH1185 |
| A | HOH1191 |
| A | HOH1209 |
| A | HOH1224 |
| A | HOH1228 |
| A | GLY10 |
| A | HOH1258 |
| A | HOH1260 |
| A | HOH1273 |
| A | HOH1282 |
| C | HOH109 |
| A | ARG11 |
| A | ILE12 |
| A | ASN35 |
| A | ASP36 |
| A | THR37 |
| A | ARG81 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | GLY305 |
| A | ASN307 |
| A | HOH1197 |
| A | HOH1220 |
| A | HOH1290 |
| A | HOH1296 |
| site_id | AC3 |
| Number of Residues | 34 |
| Details | binding site for residue NAD B 1001 |
| Chain | Residue |
| A | HOH1186 |
| A | HOH1274 |
| B | GLY8 |
| B | PHE9 |
| B | GLY10 |
| B | ARG11 |
| B | ILE12 |
| B | ASN35 |
| B | ASP36 |
| B | THR37 |
| B | ARG81 |
| B | ALA99 |
| B | THR100 |
| B | GLY101 |
| B | PHE103 |
| B | THR123 |
| B | ALA124 |
| B | CYS154 |
| B | ASN317 |
| B | TYR321 |
| B | HOH1111 |
| B | HOH1130 |
| B | HOH1133 |
| B | HOH1135 |
| B | HOH1162 |
| B | HOH1177 |
| B | HOH1187 |
| B | HOH1210 |
| B | HOH1240 |
| B | HOH1272 |
| C | ASP66 |
| C | TYR73 |
| C | HOH105 |
| C | HOH110 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1002 |
| Chain | Residue |
| B | GLY305 |
| B | ASN307 |
| B | HOH1255 |
| B | HOH1285 |
| B | HOH1291 |
| B | HOH1303 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| A | ALA152-LEU159 |
