6GEW

OphA Y63F-sinefungin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0032259	biological_process	methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue SAH A 501

Chain	Residue
A	ILE19
A	PHE171
A	GLN172
A	TYR211
A	ILE212
A	ALA213
A	GLY242
A	VAL243
A	SER244
A	THR245
A	SFG502
A	TYR98
A	HOH610
A	GLY99
A	HIS100
A	VAL103
A	PHE104
A	VAL105
A	SER129
A	ALA130

---

site_id	AC2
Number of Residues	21
Details	binding site for residue SFG A 502

Chain	Residue
A	ILE19
A	TYR98
A	GLY99
A	HIS100
A	VAL103
A	PHE104
A	VAL105
A	SER129
A	ALA130
A	PHE171
A	GLN172
A	TYR211
A	ILE212
A	ALA213
A	GLY242
A	VAL243
A	SER244
A	THR245
A	VAL403
A	SAH501
A	HOH610

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"evidences":[{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5N0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5N0O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GEW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6QZY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6QZZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6R00","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TSC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5N0O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6QZY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6QZZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5N0O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GEW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6QZY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6QZZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6R00","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TSC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5N0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5N0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GEW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"N-methylvaline","evidences":[{"source":"PubMed","id":"28715095","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30151425","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32491837","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33574430","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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