6GDE
DIHYDROOROTASE FROM AQUIFEX AEOLICUS STANDARD (P,T)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004038 | molecular_function | allantoinase activity |
| A | 0004151 | molecular_function | dihydroorotase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006145 | biological_process | purine nucleobase catabolic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 500 |
| Chain | Residue |
| A | HIS61 |
| A | HIS63 |
| A | ASP153 |
| A | ASP305 |
| A | HOH632 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00220","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15826652","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19128030","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24314009","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1XRF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XRT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BJH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00220","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24314009","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4BJH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19128030","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24314009","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3D6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BJH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
